Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

Product Name: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
CAS No.: 128625-52-5
Chemical Name: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
Synonyms: PYBOP;BOPP;BOP REAGENT;((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphoniuM hexafluorophosphate(V);(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE;1H-BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;[(1H-Benzotriazol-1-yl)oxy][tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate;BYPOP;PYBOP(R)
CBNumber: CB6434717
Molecular Formula: C18H28F6N6OP2
Formula Weight: 520.39
MOL File: 128625-52-5.mol

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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Property

Melting point:: 154-156 °C (dec.)(lit.)
Density: 1.438 at 20℃
vapor pressure: 0-0Pa at 20-50℃
storage temp.: 2-8°C
solubility: methanol: 25 mg/mL, clear
form: Fine Crystalline Powder
color: White to off-white
Sensitive: Moisture Sensitive
BRN: 3584612
InChI: InChI=1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChIKey: BYCLGHOAELJLOF-UHFFFAOYSA-M
SMILES: [P+](ON1N=NC2C=CC=CC1=2)(N1CCCC1)(N1CCCC1)N1CCCC1.[P-](F)(F)(F)(F)(F)F
LogP: -0.3 at 26℃ and pH3.5-3.7
CAS DataBase Reference: 128625-52-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-44-36/37/38
Safety Statements: 26-36-24/25-37/39
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 3
F: 8-10-21
Hazard Note: Irritant
HS Code: 29339980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51009
Product name: PyBOP
Purity: Novabiochem?
Packaging: 25g
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.51009
Product name: PyBOP
Purity: Novabiochem?
Packaging: 100g
Price: $367
Updated: 2024/03/01

Sigma-Aldrich

Product number: 12805
Product name: (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
Purity: purum, ≥97.0% (TLC)
Packaging: 1g
Price: $81.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 12805
Product name: (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
Purity: purum, ≥97.0% (TLC)
Packaging: 5G
Price: $96
Updated: 2024/03/01

Sigma-Aldrich

Product number: 12805
Product name: (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
Purity: purum, ≥97.0% (TLC)
Packaging: 25g
Price: $298
Updated: 2024/03/01

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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization.

Uses

1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl) phosphonium hexafluorophosphate is a peptide coupling reagent utilized in solid phase peptide synthesis. It is also used as a substitute for the (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.

Uses

Reagent for:
Synthesis of single labeled oligonucleotides that fluoresce upon matched hybridization
Generation of endocrine disruptor chemical binders
Cycloaddition to template-assembled multivalent peptide conjugates

General Description

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Suppliers

Americas 1 Belgium 2 Canada 5 China 390 Europe 6 France 3 Germany 8 India 23 Israel 2 Italy 1 Japan 7 Poland 1 South Korea 1 Switzerland 5 Ukraine 1 United Kingdom 18 United States 73 Global 547

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View Lastest Price from Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate 128625-52-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-09

Watson Biotechnology Co.,Ltd

Product: PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate 128625-52-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2024-09-23

Hebei Weibang Biotechnology Co., Ltd

Product: PyBOP 128625-52-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-03-14

128625-52-5, Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphateRelated Search:

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride DEPBT TSTU 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Diphenylphosphoryl azide 1H-Benzotriazole Hexafluorophosphoric acid Potassium hexafluorophosphate Lithium hexafluorophosphate Sodium hexafluorophosphate Hexafluorophosphate TRIS(DIETHYLAMINO)PHOSPHINE 1-Hydroxybenzotriazole hydrate 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate Hexamethylphosphorous triamide Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

pybop?/td>

BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHYLAMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE)

(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE

BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINPHOSPHONIUM HEXAFLUOROPHOSPHATE

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

BENZOTRIAZOLE-1-YL-OXY-TRIS-DIMETHYLAMINOPHOPHONIUM

BENZOTRIAZOL-1-YLOXYTRIS(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE

BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOPHONIUM HEXAFLUOROPHOSPHATE

BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM

BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUOROPHOSPHATE

BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE

BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRRORIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE

BOPP

BOP REAGENT

HEXAFLUOROPHOSPHATE BOP

CASTROS REAGENT

CASTRO'S REAGENT

1H-BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE

PYBOP

PYBOP(R)

Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluoroph

Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 98%

PYBOP(R),99%

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate,PyBOP

Benzotriazol-1-yl-ox

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium he

1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 98%

PyBOP (OR) Benzotriazol-1-yloxy tripyrrolidinophosphoniuM hexafluorophosphate

PYBOP, 99% 5GR

((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphoniuM hexafluorophosphate(V)

[(1H-Benzotriazol-1-yl)oxy][tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate

(1H-Benzotriazol-1-yloxy)(diMethylaMino)di(pyrrolidin-1-yl)phosphoniuM

Phosphorus(1+),[1-(hydroxy-kO)-1H-benzotriazolato]tri-1-pyrrolidinyl-,(T-4)-, hexafluorophosphate(1-) (1:1)

(1H-1,2,3-benzotriazol-1-yloxy)tris(pyrrolidin-1-yl)phosphanium

BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINO-PHOS PHONIUM

(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM F6 PHOSPHATE

PYBOP [BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE]

Benzotriazol-1-yloxytris(pyrrolidino)phosphoniumh

Benzotriazol-1-yloxytris-(pyrrolidino)-phosphonium

Benzotriazol-1-yloxytripyrroli

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphateBenzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

Benzotriazol-1-yloxytris(pyrrolidino)phosphonium Hexafluorophosphate (PyBOP)

Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphat

PYBOP ((1H-BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUMHEXAFLUOROPHOSPHATE)

Benzotriazole-1-ly-oxy-tris-pyrrolidinophosphonium hexafluorphosphate

1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate [Coupling Reagent for Peptide]

Benzotriazol-1-yl-oxytrispyrrolidinophosphonium hexafluorophosphate, 97+%

Benzotriazole-1-yl-oxy-trispyrrolidinophosphonium hexafluorophosphate ,99%

(Benzotriazol-1-yloxy)tripyrrolidinophosphoniuM hexafluorophosphate 98%

1H-Benzotriazol-1-yloxytripyrrolidinophosphoniuM hexafluorophosphate, 98.0%(LC)

1 h benzotriazole - 1 - three pyrrole alkyl six fluoride phosphate PyBOP base oxygen

enzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate≥ 99% (HPLC)

PyBOP Novabiochem

1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate

Unable to generate chemical name

BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHY

Benzotriazol-1-yloxytrispyrrolidinophosphonium hexafluorophosphate, 99%, for synthesis