ChemicalBook > CAS DataBase List > 6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE

6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE

Product Name
6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE
CAS No.
923595-49-7
Chemical Name
6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE
Synonyms
6-Chloro-3-iodoimidazo[1,2-a]pyridazine;6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE;Imidazo[1,2-b]pyridazine, 6-chloro-3-iodo-;6-Chloro-3-iodoimidazo[1,2-a]pyridazine;6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE ISO 9001:2015 REACH
CBNumber
CB11501796
Molecular Formula
C6H3ClIN3
Formula Weight
279.47
MOL File
923595-49-7.mol
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6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE Property

Density 
2.34
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
1.03±0.30(Predicted)
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C6H3ClIN3/c7-4-1-2-6-9-3-5(8)11(6)10-4/h1-3H
InChIKey
IWHCPHZAMFSDFM-UHFFFAOYSA-N
SMILES
C12=NC=C(I)N1N=C(Cl)C=C2
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00424
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridazine
Packaging
1g
Price
$58.6
Updated
2025/07/31
AK Scientific
Product number
5602AC
Product name
6-Chloro-3-iodoimidazo[1,2-b]pyridazine
Packaging
250mg
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
070531
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridazine
Purity
96%
Packaging
1g
Price
$908
Updated
2021/12/16
Matrix Scientific
Product number
070531
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridazine
Purity
96%
Packaging
5g
Price
$1571
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0105389
Product name
6-CHLORO-3-IODOIMIDAZO(1,2B)PYRIDAZINE
Purity
95.00%
Packaging
1G
Price
$1575.42
Updated
2021/12/16
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6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE Chemical Properties,Usage,Production

Synthesis

6775-78-6

923595-49-7

The general procedure for the synthesis of 6-chloro-3-iodoimidazo[1,2-b]pyridazine using 6-chloroimidazo[1,2-b]pyridazine as starting material was as follows: 6-chloroimidazo[1,2-b]pyridazine (2.0 g, 13.0 mmol, 1.0 equiv) was dissolved in chloroform (20 mL) at room temperature. Subsequently, iodosuccinimide (2.9 g, 13.0 mmol, 1.0 eq.) was added to this solution and the reaction mixture was vigorously stirred overnight at room temperature. After completion of the reaction, the mixture was diluted with water and extracted with ethyl acetate. The extract was purified by column chromatography, resulting in 3.3 g of yellow solid product in 90% yield. The structure of the product was confirmed by 1H NMR: δ 8.21 (d, J = 7.6 Hz, 1H), 7.96 (s, 1H), 7.41 (d, J = 7.6 Hz, 1H).

References

[1] Patent: US2014/256733, 2014, A1. Location in patent: Page/Page column 0227; 0230-0231
[2] MedChemComm, 2018, vol. 9, # 10, p. 1733 - 1745
[3] Patent: EP2818471, 2014, A1. Location in patent: Paragraph 0120; 0121
[4] Patent: WO2013/34048, 2013, A1. Location in patent: Page/Page column 77; 78
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2789 - 2798

6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE Suppliers

SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
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918
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55
Shanghai Paulshine Chemical Co., Ltd.
Tel
+86-021-37788663
Fax
+86-021-37788663
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China
ProdList
186
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64
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
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China
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Wuhan Kaymke Chemical Co., Ltd.,
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027-027-87342388 18086026008
Fax
027-87342388
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sales@kaymke.com
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China
ProdList
3731
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Shanghai Yolne Chemical Co., Ltd.
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021-62960152
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021-52212593
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934678158@qq.com
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China
ProdList
9899
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55
Bide Pharmatech Ltd.
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400-164-7117 13681763483
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+86-21-61629029
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product02@bidepharm.com
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China
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Modachem Shanghai Co., Ltd
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+86 (0)21 51320687 51371369 1744605818
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+86 (0)21 51371369
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China
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ShangHai KenEn Chemical Technology Co., Ltd.
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13120367189
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021-50315529
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mychess007@163.com
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China
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1994
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Shanghai Xingui Biotechnology Co., Ltd.
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15121041756
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xingui2022@126.com
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China
ProdList
9979
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ShangHai AmK Pharmaceutical Technology Co., Ltd.
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微信 17321281695 18019252918
Fax
17321281695
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sale@amkchem.com
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China
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15136
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View Lastest Price from 6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
6-chloro-3-iodoimidazo[1,2-b]pyridazine 923595-49-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-04-30
Shanghai Rlavie Technology Co ltd
Product
6-chloro-3-iodoimidazo[1,2-b]pyridazine 923595-49-7
Price
US $0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
50kgs/month
Release date
2021-11-10
Dideu Industries Group Limited
Product
6-CHLORO-3-IODOIMIDAZO[1,2-B]PYRIDAZINE 923595-49-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-02