6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

Product Name: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
CAS No.: 22245-98-3
Chemical Name: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
Synonyms: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE;3,4-Dihydro-6-hydroxy-1(2H)-isoquinolinone;3,4-Dihydro-6-hydroxyisoquinolin-1(2H)-one;1(2H)-Isoquinolinone,3,4-dihydro-6-hydroxy-;6-Hydroxy-2- Oxo-1,2,3,4-Tetrahydroquinolene;6-hydroxy-1,2,3,4-tetrahydroisoquinolin-1-one;6-Hydroxy-3,4-dihydro-1-oxo-2(1H)-isoquinoline;6-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone ,97%
CBNumber: CB11508164
Molecular Formula: C9H9NO2
Formula Weight: 163.17
MOL File: 22245-98-3.mol

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6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Property

storage temp.: Storage temp. 2-8°C
Appearance: White to off-white Solid

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Safety

HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: H947918
Product name: 6-Hydroxy-3,4-dihydro-2h-isoquinolin-1-one
Packaging: 100mg
Price: $95
Updated: 2021/12/16

Matrix Scientific

Product number: 118890
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 95+%
Packaging: 500mg
Price: $101
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 1g
Price: $104
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 100mg
Price: $27
Updated: 2021/12/16

Ark Pharm

Product number: P000537185
Product name: 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
Purity: 98%
Packaging: 250mg
Price: $38
Updated: 2021/12/16

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6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Chemical Properties,Usage,Production

Synthesis

22246-12-4

22245-98-3

Step 1: 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one (2.58 g, 14 mmol) was dissolved in dichloromethane at -78 °C and boron tribromide (2.7 mL, 28 mmol) was slowly added. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched with cold water and subsequently extracted with ethyl acetate. The organic phases were combined and concentrated in vacuum to remove the solvent. The crude product was purified by ISCO CombiFlash? system using silica gel column chromatography with a dichloromethane solution of 0-15% methanol as eluent to afford 6-hydroxy-3,4-dihydroisoquinolin-1-one as a light brown solid (1.8 g, 75% yield) with a melting point of 204-206 °C; mass spectrum (electrospray ionization) m/z 162.1 [M+H ]+.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 814 - 819
[2] Patent: US2009/69300, 2009, A1. Location in patent: Page/Page column 23
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 5, p. 2452 - 2468
[4] Patent: US2003/225122, 2003, A1. Location in patent: Page 18-19
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 16, p. 4727 - 4730

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Suppliers

China 56 India 4 Ukraine 1 United Kingdom 1 United States 8 Global 70

Alchem Pharmtech,Inc.

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Aladdin Scientific

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Matrix Scientific

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Sinova Inc.

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View Lastest Price from 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 22245-98-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-19

Career Henan Chemical Co

Product: 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 22245-98-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-14

22245-98-3, 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONERelated Search:

narciclasine 6-METHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 6,7-DIMETHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 7,8-DIHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5(6H)-ONE 6,7-DIHYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE AKOS 236-23 AKOS 237-34 AKOS 214-22 AKOS 214-30 AKOS 214-58 6-METHOXY-2-(3-METHOXY-PHENYL)-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 2,2,2-TRIFLUORO-N-(5-OXO-5,6,7,8-TETRAHYDRO[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-8-YL)ACETAMIDE N-(6,7-DIMETHOXY-1-OXO-1,2,3,4-TETRAHYDRO-4-ISOQUINOLINYL)-2,2,2-TRIFLUOROACETAMIDE 6-METHOXY-2-PHENYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE AKOS 233-98 AKOS 213-63 8-AMINO-7,8-DIHYDRO-6H-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-ONE HCL

6-HYDROXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

6-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone ,97%

6-hydroxy-1,2,3,4-tetrahydroisoquinolin-1-one

1(2H)-Isoquinolinone,3,4-dihydro-6-hydroxy-

3,4-Dihydro-6-hydroxyisoquinolin-1(2H)-one

3,4-Dihydro-6-hydroxy-1(2H)-isoquinolinone

6-Hydroxy-3,4-dihydro-1-oxo-2(1H)-isoquinoline

6-Hydroxy-2- Oxo-1,2,3,4-Tetrahydroquinolene

22245-98-3