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befiradol

Product Name
befiradol
CAS No.
208110-64-9
Chemical Name
befiradol
Synonyms
F 13640;NLX 112);befiradol;Unii-rat9oha1yh;Befiradol (F 13640;NLX-112 hydrochloride;1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methyl-2-pyridinyl)methyl]-4-piperidinemethanamine;(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone;Methanone, (3-chloro-4-fluorophenyl)[4-fluoro-4-[[[(5-methyl-2-pyridinyl)methyl]amino]methyl]-1-piperidinyl]-;Befiradol/NLX-112/F13640/(3-Chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone
CBNumber
CB11518495
Molecular Formula
C20H22ClF2N3O
Formula Weight
393.86
MOL File
208110-64-9.mol
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befiradol Property

Boiling point:
536.9±50.0 °C(Predicted)
Density 
1.30
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
8.01±0.20(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2324
Product name
NLX-112hydrochloride
Purity
≥98%(HPLC)
Packaging
5mg
Price
$132
Updated
2025/07/31
Sigma-Aldrich
Product number
SML2324
Product name
NLX-112hydrochloride
Purity
≥98%(HPLC)
Packaging
25mg
Price
$528
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
API0026899
Product name
BEFIRADOL
Purity
95.00%
Packaging
0.5MG
Price
$632.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0026899
Product name
BEFIRADOL
Purity
95.00%
Packaging
1MG
Price
$721.88
Updated
2021/12/16
DC Chemicals
Product number
DC21007
Product name
Befiradol
Purity
>98%
Packaging
100mg
Price
$500
Updated
2021/12/16
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befiradol Chemical Properties,Usage,Production

Uses

Befiradol (NLX-112) is a selective 5-HT1A receptor agonist.

Biological Activity

NLX-112 (also known as befiradol or F13640) is a highly selective 5-HT1A receptor full agonist with >1000-fold selectivity compared to other types of receptors. It has been investigated for the treatment of Parkinsonμs disease patients who exhibit L-DOPA-induced dyskinesia

IC 50

5-HT1A Receptor

References

[1] Lladó-Pelfort L, et al. In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat. Psychopharmacology (Berl). 2012 May;221(2):261-72. DOI:10.1007/s00213-011-2569-9

befiradol Preparation Products And Raw materials

Raw materials

Preparation Products

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befiradol Suppliers

China 33 Germany 1 India 2 United States 5 Global 41
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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TargetMol Chemicals Inc.
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+17819995354
Email
marketing@targetmol.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354;
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support@targetmol.com
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United States
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MedChemExpress
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Alfa Chemistry
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United States
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208110-64-9, befiradolRelated Search:

N-(4-FLUOROBENZOYL)PIPERIDINE (1-Benzyl-4-piperidinyl)methylamine 4-FLUOROPIPERIDINE HYDROCHLORIDE 3-Chloro-4-fluorobenzylamine 3-CHLORO-4-FLUOROBENZAMIDE 1-(1-BENZYLPIPERIDIN-4-YL)-N-METHYLMETHANAMINE OTAVA-BB 1127481 4-FLUOROPIPERIDINE befiradol

  • befiradol
  • 1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methyl-2-pyridinyl)methyl]-4-piperidinemethanamine
  • Unii-rat9oha1yh
  • F 13640
  • (3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
  • Befiradol (F 13640
  • NLX 112)
  • Methanone, (3-chloro-4-fluorophenyl)[4-fluoro-4-[[[(5-methyl-2-pyridinyl)methyl]amino]methyl]-1-piperidinyl]-
  • Befiradol/NLX-112/F13640/(3-Chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone
  • NLX-112 hydrochloride
  • 208110-64-9
  • C20H22ClF2N3O