1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL

Product Name: 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL
CAS No.: 75144-12-6
Chemical Name: 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL
Synonyms: Antitrypanosomal agent 1;1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one;1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL;1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanonehydrochloride;1-Propanone1-(34-dichlorophenyl)-3-(dimethylamino)-hydrochloride;1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride;Antitrypanosomal agent-1,Antitrypanosomal agent 1,T.brucei,trypanothione,inhibit,glutathione,Antitrypanosomal agent1,Inhibitor,reductase,Parasite,anti-trypanosomal
CBNumber: CB11519588
Molecular Formula: C11H14Cl3NO
Formula Weight: 282.59
MOL File: 75144-12-6.mol

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1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Property

Melting point:: 186 - 188°C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Off-White
Water Solubility: Water: 10 mg/mL (35.39 mM)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D435873
Product name: 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanoneHydrochloride
Packaging: 50mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-0045380
Product name: Antitrypanosomalagent1
Packaging: 1g
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: 1400AL
Product name: 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanoneHCl
Packaging: 1g
Price: $151
Updated: 2021/12/16

ChemScene

Product number: CS-0045380
Product name: Antitrypanosomalagent1
Packaging: 5g
Price: $276
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0063405
Product name: 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HYDROCHLORIDE
Purity: 95.00%
Packaging: 1G
Price: $713.1
Updated: 2021/12/16

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1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Chemical Properties,Usage,Production

Biological Activity

Antitrypanosomal agent 1 is a potent and selective inhibitor of trypanothione reductase with IC50 of 3.3 μM. It inhibits glutathione reductase with IC50 of 64.8 μM; inhibits Trypanosoma brucei with EC50 of 1 μM. It has antitrypanosomal activity.

in vitro

Antitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.

target

IC50: 3.3 μM (trypanothione reductase) and 64.8 μM (glutathione reductase)
EC50: 1 μM ( T. brucei )

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Suppliers

China 39 India 1 United States 5 Global 45

J & K SCIENTIFIC LTD.

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75144-12-6, 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCLRelated Search:

1-(4-CHLOROPHENYL)-3-(DIMETHYLAMINO)PROPAN-1-ONE HYDROCHLORIDE 3',4'-DICHLOROPROPIOPHENONE 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL

1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanonehydrochloride

1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride

Antitrypanosomal agent 1

1-Propanone1-(34-dichlorophenyl)-3-(dimethylamino)-hydrochloride

1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one

Antitrypanosomal agent-1,Antitrypanosomal agent 1,T.brucei,trypanothione,inhibit,glutathione,Antitrypanosomal agent1,Inhibitor,reductase,Parasite,anti-trypanosomal

75144-12-6