5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE
- Product Name
- 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE
- CAS No.
- 745053-64-9
- Chemical Name
- 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE
- Synonyms
- 5-Fluorothiazol-2-aMine HCl;2-Amine-5-Fluorothiazol HCL;2-AMino-5-fluorothiazole HCl;5-Fluoro-thiazol-2-ylamine HCl;5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE;5-Fluroro-2-thiazolaMine hydrochloride;5-Fluorothiazole-2-aMine hydrochloride;2-ThiazolaMine,5-fluoro-, hydrochloride;5-Fluoro-thiazol-2-ylamine hydrochloride;2-Amino-5-fluorothiazole hydrochloride 95%
- CBNumber
- CB11559999
- Molecular Formula
- C3H3FN2S.HCl
- Formula Weight
- 154.59
- MOL File
- 745053-64-9.mol
5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE Property
- Melting point:
- 138-143°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- Yellow to brown Solid
- CAS DataBase Reference
- 745053-64-9
Safety
- WGK Germany
- 3
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 754153
- Product name
- 2-Amino-5-fluorothiazole hydrochloride
- Purity
- 95%
- Packaging
- 250mg
- Price
- $77.3
- Updated
- 2023/01/07
- Product number
- F596023
- Product name
- 5-Fluorothiazol-2-amineHydrochloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F596023
- Product name
- 5-Fluorothiazol-2-amineHydrochloride
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA168284
- Product name
- 2-Amino-5-fluorothiazole hydrochloride
- Packaging
- 5G
- Price
- $600
- Updated
- 2021/12/16
- Product number
- 37993
- Product name
- 5-Fluorothiazol-2-amineHCl
- Purity
- 95+%
- Packaging
- 5G
- Price
- $660
- Updated
- 2021/12/16
5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
5-Fluorothiazol-2-amine Hydrochloride can be used as anti-tumor agents.
Synthesis
731018-54-5
745053-64-9
b) Synthesis of 5-fluorothiazol-2-amine hydrochloride; N-(5-fluoro-2-thiazolyl)-carbamic acid-1,1-dimethylethyl ester (4.6 g, 21.1 mmol) was dissolved in dioxane (25 mL). HCl gas was passed into the solution for 4 h. Subsequently, ether (50 mL) was added to form a suspension and the solid was collected by filtration. The resulting solid was dried under high vacuum to give 5-fluorothiazol-2-amine hydrochloride (3.03 g, 19.7 mmol, 93% yield). The product was confirmed by 1H NMR (D2O): δ 7.00 (1H, d); mass spectrometry analysis showed m/z = 119.0 [M + H]+.
References
[1] Organic Process Research and Development, 2006, vol. 10, # 2, p. 346 - 348
[2] Patent: WO2006/16178, 2006, A1. Location in patent: Page/Page column 9
[3] Patent: WO2006/16174, 2006, A1. Location in patent: Page/Page column 17
[4] Patent: EP2105435, 2009, A1. Location in patent: Page/Page column 54-55
[5] Patent: WO2012/51450, 2012, A1. Location in patent: Page/Page column 28
5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE manufacturers
- Product
- 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE 745053-64-9
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12