N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
- Product Name
- N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
- CAS No.
- 916603-07-1
- Chemical Name
- N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
- Synonyms
- CZC-8004;CZC 00008004;DianilinopyriMidine_01;Dianilinopyrimidine_01(CZC8004);N-(4-broMophenyl)-N-(naphthalen-2-yl);N-(4-broMophenyl)-N-(naphthalen-2-yl) naphthalen-1-aMine;Target-5 (Kinase Probe Tool, APM-1)/Dianilinopyrimidine_01;N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-...;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine
- CBNumber
- CB11565156
- Molecular Formula
- C17H16FN5
- Formula Weight
- 309.34
- MOL File
- 916603-07-1.mol
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Property
- Boiling point:
- 514.1±60.0 °C(Predicted)
- Density
- 1.332
- storage temp.
- -20°
- solubility
- Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming)
- pka
- 9.14±0.10(Predicted)
- form
- solid
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P234Keep only in original container.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16718
- Product name
- CZC-8004
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 16718
- Product name
- CZC-8004
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $143
- Updated
- 2024/03/01
- Product number
- 16718
- Product name
- CZC-8004
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $396
- Updated
- 2024/03/01
- Product number
- 16718
- Product name
- CZC-8004
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $632
- Updated
- 2024/03/01
- Product number
- A617370
- Product name
- N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
- Packaging
- 10mg
- Price
- $500
- Updated
- 2021/12/16
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Chemical Properties,Usage,Production
Description
CZC-8004 (916603-07-1) is a pan-specific kinase inhibitor. May be coupled to sepharose via its amino-side chain for affinity chromatography applications1.
Uses
A novel enzyme-interacting compounds using immobilized broad-spectrum ligands
Uses
CZC-8004 is an aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be immobilized to capture and purify these enzymes.
Definition
ChEBI: CZC8004 is an aminopyrimidine and an organofluorine compound. It has a role as a protein kinase inhibitor.
References
1) Klutchko?et al. (1998),?2-Substituted aminopyrido[2,3-d]pyrilidin-7(8H)-ones, structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity; J. Med. Chem.,?41?3276
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine manufacturers
- Product
- CZC8004 916603-07-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-02-05