BOC-D-ORN(Z)-OH

Product Name: BOC-D-ORN(Z)-OH
CAS No.: 16937-92-1
Chemical Name: BOC-D-ORN(Z)-OH
Synonyms: BOC-D-ORN(Z)-OH;Boc-D-Orn(Cbz)-OH;BOC-D-ORNITHINE(CBZ);BOC-D-ORNITHINE(Z)-OH;nα-boc-nδ-z-d-ornithine;N-Boc-N'-Cbz-D-Ornithine;Boc-D-Orn(Z)-OH;N2-Boc-N5-Cbz-D-ornithine;BOC-N-DELTA-Z-D-ORNITHINE;BOC-D-ORN(Z)-OH USP/EP/BP
CBNumber: CB1157611
Molecular Formula: C18H26N2O6
Formula Weight: 366.41
MOL File: 16937-92-1.mol

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BOC-D-ORN(Z)-OH Property

Boiling point:: 579.1±50.0 °C(Predicted)
Density: 1.193±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.96±0.21(Predicted)
form: Solid
BRN: 2400891
InChIKey: QYYCZJUFHDLLOJ-CQSZACIVSA-N
CAS DataBase Reference: 16937-92-1

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15193
Product name: Boc-D-Orn(Z)-OH
Purity: ≥98.0% (TLC)
Packaging: 5g
Price: $642
Updated: 2023/06/20

TRC

Product number: B802775
Product name: Boc-D-Orn(Z)-OH
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 05512
Product name: -Boc--Z-D-ornithine
Purity: ≥ 99% (HPLC)
Packaging: 1G
Price: $15
Updated: 2021/12/16

AK Scientific

Product number: J51445
Product name: Boc-D-Orn(Z)-OH
Packaging: 1g
Price: $30
Updated: 2021/12/16

Activate Scientific

Product number: AS112805
Product name: D-Boc-Orn(Cbz)-OH
Purity: 97%
Packaging: 1g
Price: $52
Updated: 2021/12/16

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BOC-D-ORN(Z)-OH Chemical Properties,Usage,Production

Uses

peptide synthesis

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

24424-99-5

16937-91-0

2480-93-5

General procedure for the synthesis of N-tert-butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine from di-tert-butyl dicarbonate and N'-Cbz-D-Ornithine: N'-Cbz-D-Ornithine (22 g, 82.6 mmol) was dissolved or suspended in an aqueous solution (250 mL) of potassium carbonate (12.56 g, 90.9 mmol), followed by addition of 1,4-dioxane (100 mL). A solution of di-tert-butyl dicarbonate (18.93 g, 86.75 mmol) dissolved in 1,4-dioxane (200 mL) was added slowly and dropwise to the reaction mixture over 60 minutes. The reaction mixture was stirred overnight at room temperature and subsequently concentrated under reduced pressure to about 150 mL. water (50 mL) was added and the pH was adjusted to 2-3 with 1 M aqueous hydrochloric acid (about 150 mL). extraction was carried out with ethyl acetate (first 400 mL, then 3 x 300 mL), and the organic phases were combined, and the reaction was carried out in sequence with 10 mM aqueous hydrochloric acid (100 mL), saturated NH4Cl aqueous solution (200 mL) and water (100 mL) to wash. Finally, it was washed with brine (250 mL) and dried over sodium sulfate. After filtration, the solvent was evaporated to give a pale yellow oil, which gradually became foamy and eventually hardened to a solid during vacuum drying (27.8 g, 92% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ (ppm) 1.38 (s, 9H), 1.4-1.59 (m, 3H), 1.65 (m, 1H), 2.98 (m, 2H), 3.83 (m, 1H), 5.0 (s, 2H), 7.07 (d, 1H, 3J = 8.0 Hz), 7.25 (t. 1H, 3J = 5.5Hz), 7.34 (m, 5H), 12.42 (s, 1H); molecular formula C18H28N2O6 (molecular weight 366.4).

References

[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 9, p. 2859 - 2878

BOC-D-ORN(Z)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-ORN(Z)-OH Suppliers

China 94 India 2 Japan 3 Switzerland 1 United Kingdom 2 United States 10 Global 112

Alfa Aesar

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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ChemPep, Inc.

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Shanghai Topbiochem Technology Co., Ltd

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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9ding chemical ( Shanghai) Limited

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View Lastest Price from BOC-D-ORN(Z)-OH manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: BOC-D-ORN(Z)-OH 16937-92-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-07

Career Henan Chemical Co

Product: N-Boc-N'-Cbz-D-Ornithine 16937-92-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

16937-92-1, BOC-D-ORN(Z)-OHRelated Search:

BOC-O-DIBENZYLPHOSPHO-L-SERINE BOC-LYS(AC)-OH BOC-DAP(Z)-OH BOC-L-BETA-HOMOLEUCINE BOC-D-PRO-OSU 3-(3-BROMO-PHENYL)-3-TERT-BUTOXYCARBONYLAMINO-PROPIONIC ACID BOC-D-MEPHE-OH DCHA N-Boc-Ethylenediamine Boc-O-tert-butyl-L-threonine BOC-GLU(OFM)-OH BOC-D-ORN(Z)-OH tert-Butyl 4-(methylamino)butylcarbamate BOC-L-ORN(BOC)-OH 5-(Z-AMINO)-1-PENTANOL Boc-L-Orn(Cbz)-OH,BOC-L-ORN(Z)-OH L-Ornithine BOC-L-ORN(PYRAZINYLCARBONYL)-OH BOC-D-ORN(BOC)-OH

(R)-12,12-dimethyl-3,10-dioxo-1-phenyl-2,11-dioxa-4,9-diazatridecane-8-carboxylic acid

Boc-N-delta-Cbz-D-ornithine

N^d-Benzyloxycarbonyl-N^a-Boc-D-ornithine, 98%

(R)-5-(((Benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)pentanoic acid

Nα-Boc-Nδ-Z-D-ornithine≥ 99% (HPLC)

Ndelta-Benzyloxycarbonyl-Nalpha-Boc-D-ornithine

BOC-D-ORNITHINE(CBZ)

BOC-D-ORNITHINE(Z)-OH

N2-Boc-N5-Cbz-D-ornithine

5-amino-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]-phenylmethoxycarbonylamino]pentanoic acid

(2R)-5-{[(benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}pentanoic acid

BOC-D-ORN(Z)-OH

BOC-N-DELTA-Z-D-ORNITHINE

N-DELTA-Z-N-ALPHA-BOC-D-ORNITHINE

N-ALPHA-BOC-N-DELTA-Z-D-ORNITHINE

N-ALPHA-BUTOXYCARBONYL-N-DELTA-CARBOBENZOXY-D-ORNITHINE

Nα-Boc-Nδ-Z-D-ornithine, Nδ-Z-Nα-Boc-D-ornithine

N-Boc-N'-Cbz-D-Ornithine

nα-boc-nδ-z-d-ornithine

N5-Benzyloxycarbonyl-N2-tert-butoxycarbonyl-D -ornithine

Boc-D-Orn(Cbz)-OH

(Tert-Butoxy)Carbonyl D-Orn(Z)-OH

D-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[(phenylmethoxy)carbonyl]-

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(phenylmethoxycarbonylamino)pentanoicaci

BOC-D-ORN(Z)-OH USP/EP/BP

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(phenylmethoxycarbonylamino)pentanoic acid

N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[(phenylmethoxy)carbonyl]-D-ornithine

Boc-<sc>D</sc>-Orn(Z)-OH

16937-92-1

Ornithine

Peptide Synthesis

Specialty Synthesis

Unnatural Amino Acid Derivatives

Ornithine [Org]