4-(Piperazino)indole

Product Name: 4-(Piperazino)indole
CAS No.: 84807-09-0
Chemical Name: 4-(Piperazino)indole
Synonyms: 4-(Piperazino)indole;4-PIPERAZINO-1H-INDOLE;4-(1-Piperazinyl)indole;1-(4-Indolyl)piperazine;4-(1-piperazinyl)-1h-indol;4-(1-PIPERAZINYL)-1H-INDOLE;1H-Indole, 4-(1-piperazinyl)-
CBNumber: CB1158799
Molecular Formula: C12H15N3
Formula Weight: 201.27
MOL File: 84807-09-0.mol

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4-(Piperazino)indole Property

Melting point:: 204-206°C
Boiling point:: 421.5±25.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
RTECS: NM1302400
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: soluble in DMSO, Water
pka: 18.78±0.30(Predicted)
form: Solid
CAS DataBase Reference: 84807-09-0

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: P481250
Product name: 4-(1-Piperazinyl)-1H-indoleDihydrochloride
Packaging: 250mg
Price: $1110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0010987
Product name: 4-(1-PIPERAZINYL)-1H-INDOLE
Purity: 95.00%
Packaging: 250MG
Price: $1871.1
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 13113
Product name: 4-(1-Piperazinyl)-1H-indole
Packaging: 250mg
Price: $1880
Updated: 2021/12/16

Matrix Scientific

Product number: 072953
Product name: 4-(1-Piperazinyl)-1H-indole
Purity: 95+%
Packaging: 5g
Price: $2411
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0010987
Product name: 4-(1-PIPERAZINYL)-1H-INDOLE
Purity: 95.00%
Packaging: 25MG
Price: $739.2
Updated: 2021/12/16

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4-(Piperazino)indole Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

4-(1-Piperazinyl)-1H-indole Dihydrochloride (cas# 84807-09-0) is a compound useful in organic synthesis.

Synthesis

5192-23-4

821-48-7

84807-09-0

To the reaction solution, 4-aminoindole (2 g, 15.2 mmol), bis(2-chloroethyl)amine hydrochloride (3.2 g, 18.2 mmol) and potassium carbonate (4.2 g, 30.4 mmol) were added sequentially to isopropanol (30 mL). The reaction mixture was stirred at 90 °C for 48 hours. Upon completion of the reaction, the mixture was diluted by adding dichloromethane (50 mL) and methanol (50 mL) to the mixture. The reaction mixture was filtered to remove insoluble matter and the filtrate was concentrated under reduced pressure and dried by rotary evaporator. Finally, the residue was purified using silica gel column chromatography (eluent ratio of dichloromethane/methanol (v/v) = 10/1) to afford the target product 4-(1-piperazinyl)-1H-indole as a brown solid (2.78 g, 90.8% yield).

References

[1] Patent: CN105367472, 2016, A. Location in patent: Paragraph 0179; 0180; 0181; 0182
[2] Patent: US2008/318941, 2008, A1. Location in patent: Page/Page column 19-20

4-(Piperazino)indole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Piperazino)indole Suppliers

Canada 1 China 51 Germany 2 India 1 United Kingdom 2 United States 11 Global 68

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4-(1-piperazinyl)-1h-indol

4-(1-PIPERAZINYL)-1H-INDOLE

4-PIPERAZINO-1H-INDOLE

4-(Piperazino)indole

1H-Indole, 4-(1-piperazinyl)-

1-(4-Indolyl)piperazine

4-(1-Piperazinyl)indole

84807-09-0

Indole Derivatives