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SDZ 216-525

Product Name
SDZ 216-525
CAS No.
141533-35-9
Chemical Name
SDZ 216-525
Synonyms
SDZ 216-525
CBNumber
CB51395726
Molecular Formula
C25H28N4O5S
Formula Weight
496.585
MOL File
141533-35-9.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
BRS0000743
Product name
SDZ 216-525
Purity
95.00%
Packaging
5MG
Price
$504.31
Updated
2021/12/16
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SDZ 216-525 Chemical Properties,Usage,Production

Description

SDZ-216525 is a 5-HT1A receptor antagonist which significantly inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).

Uses

SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor[1][2].

References

[1] Boddeke H W G M, et al. Agonist/antagonist interactions with cloned human 5-HT 1A receptors: variations in intrinsic activity studied in transfected HeLa cells[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1992, 345: 257-263. DOI:10.1007/BF00168684
[2] Sharp T, et al. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo[J]. British journal of pharmacology, 1993, 109(3): 699-702. DOI:10.1111/j.1476-5381.1993.tb13630.x

SDZ 216-525 Preparation Products And Raw materials

Raw materials

Preparation Products

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SDZ 216-525 Suppliers

TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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Jinan ponder chemical co. LTD
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0531-0000
Email
thinklifescience@163.com
Country
China
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
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29358
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TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
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58