N-alpha-Cbz-L-2,4-diamiobutyric acid
- Product Name
- N-alpha-Cbz-L-2,4-diamiobutyric acid
- CAS No.
- 62234-40-6
- Chemical Name
- N-alpha-Cbz-L-2,4-diamiobutyric acid
- Synonyms
- CBZ-DAB;Z-DAB-OH;Z-Dbu-OH;Z-L-DAB-OH;Cbz-Dab-OH;Z-L-2,4-DIAMINOBUTYRIC ACID;Cbz-L-2,4-diaminobutyric acid;Nα-Z-L-2,4-diaminobutyric acid;N-α-Z-D-2,4-diaminobutyric acid;N-α-Cbz-L-2,4-DiaMiobutyric acid
- CBNumber
- CB1161713
- Molecular Formula
- C12H16N2O4
- Formula Weight
- 252.27
- MOL File
- 62234-40-6.mol
N-alpha-Cbz-L-2,4-diamiobutyric acid Property
- Melting point:
- 194-196 °C
- alpha
- -9.5 º (c=1%, H2O)
- Boiling point:
- 480.3±45.0 °C(Predicted)
- Density
- 1.266±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- pka
- 3.62±0.10(Predicted)
- form
- Powder
- color
- Pale brown
- optical activity
- -6.9°(C=0.01g/ml H2O)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A600220
- Product name
- (S)-4-Amino-2-(benzyloxycarbonylamino)butyricAcid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A600220
- Product name
- (S)-4-Amino-2-(benzyloxycarbonylamino)butyricAcid
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FD48843
- Product name
- N-alpha-Z-L-2,4-diaminobutyric acid
- Packaging
- 1g
- Price
- $74.6
- Updated
- 2021/12/16
- Product number
- FD48843
- Product name
- N-alpha-Z-L-2,4-diaminobutyric acid
- Packaging
- 2g
- Price
- $130.3
- Updated
- 2021/12/16
- Product number
- W7429
- Product name
- Z-Dab-OH
- Packaging
- 5g
- Price
- $166
- Updated
- 2021/12/16
N-alpha-Cbz-L-2,4-diamiobutyric acid Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
N-alpha-Z-D-2,4-Diaminobutyric Acid
Synthesis
2650-64-8
62234-40-6
The general procedure for the synthesis of (S)-4-amino-2-(((benzyloxy)carbonyl)amino)butyric acid from N-benzyloxycarbonyl-L-glutamine was as follows: 14 g of N-benzyloxycarbonyl-L-glutamine was dissolved in a solvent mixture of 80 mL of ethyl acetate and 20 mL of tetrahydrofuran, 50 mL of water was added, and the reaction mixture was cooled to 0°C. Subsequently, 60 g of bis(trifluoroacetic acid)iodobenzene were added slowly , and the reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the aqueous layer was separated and the organic layer was washed three times with distilled water. All aqueous layers were combined and concentrated by vacuum distillation. The concentrated aqueous solution was stirred with anhydrous ethanol to promote crystallization and the crystalline product was collected by filtration. The crystals were washed twice with ethanol and dried by filtration. Finally, the product was dried at 60°C to give 5 g of the target compound with a melting point of 182-186°C.
References
[1] Synthetic Communications, 2004, vol. 34, # 6, p. 1049 - 1056
[2] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 2, p. 355 - 360
[3] FEBS Journal, 2013, vol. 280, # 8, p. 1807 - 1817
[4] Tetrahedron Letters, 1993, vol. 34, # 28, p. 4493 - 4496
[5] Chemical Communications, 2013, vol. 49, # 29, p. 2977 - 2979
N-alpha-Cbz-L-2,4-diamiobutyric acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-alpha-Cbz-L-2,4-diamiobutyric acid manufacturers
- Product
- N-alpha-Cbz-L-2,4-diamiobutyric acid 62234-40-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-03