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N-alpha-Cbz-L-2,4-diamiobutyric acid

Product Name
N-alpha-Cbz-L-2,4-diamiobutyric acid
CAS No.
62234-40-6
Chemical Name
N-alpha-Cbz-L-2,4-diamiobutyric acid
Synonyms
CBZ-DAB;Z-DAB-OH;Z-Dbu-OH;Z-L-DAB-OH;Cbz-Dab-OH;Z-L-2,4-DIAMINOBUTYRIC ACID;Cbz-L-2,4-diaminobutyric acid;Nα-Z-L-2,4-diaminobutyric acid;N-α-Z-D-2,4-diaminobutyric acid;N-α-Cbz-L-2,4-DiaMiobutyric acid
CBNumber
CB1161713
Molecular Formula
C12H16N2O4
Formula Weight
252.27
MOL File
62234-40-6.mol
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N-alpha-Cbz-L-2,4-diamiobutyric acid Property

Melting point:
194-196 °C
alpha 
-9.5 º (c=1%, H2O)
Boiling point:
480.3±45.0 °C(Predicted)
Density 
1.266±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
pka
3.62±0.10(Predicted)
form 
Powder
color 
Pale brown
optical activity
-6.9°(C=0.01g/ml H2O)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A600220
Product name
(S)-4-Amino-2-(benzyloxycarbonylamino)butyricAcid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
A600220
Product name
(S)-4-Amino-2-(benzyloxycarbonylamino)butyricAcid
Packaging
500mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD48843
Product name
N-alpha-Z-L-2,4-diaminobutyric acid
Packaging
1g
Price
$74.6
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD48843
Product name
N-alpha-Z-L-2,4-diaminobutyric acid
Packaging
2g
Price
$130.3
Updated
2021/12/16
AK Scientific
Product number
W7429
Product name
Z-Dab-OH
Packaging
5g
Price
$166
Updated
2021/12/16
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N-alpha-Cbz-L-2,4-diamiobutyric acid Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

N-alpha-Z-D-2,4-Diaminobutyric Acid

Synthesis

2650-64-8

62234-40-6

The general procedure for the synthesis of (S)-4-amino-2-(((benzyloxy)carbonyl)amino)butyric acid from N-benzyloxycarbonyl-L-glutamine was as follows: 14 g of N-benzyloxycarbonyl-L-glutamine was dissolved in a solvent mixture of 80 mL of ethyl acetate and 20 mL of tetrahydrofuran, 50 mL of water was added, and the reaction mixture was cooled to 0°C. Subsequently, 60 g of bis(trifluoroacetic acid)iodobenzene were added slowly , and the reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the aqueous layer was separated and the organic layer was washed three times with distilled water. All aqueous layers were combined and concentrated by vacuum distillation. The concentrated aqueous solution was stirred with anhydrous ethanol to promote crystallization and the crystalline product was collected by filtration. The crystals were washed twice with ethanol and dried by filtration. Finally, the product was dried at 60°C to give 5 g of the target compound with a melting point of 182-186°C.

References

[1] Synthetic Communications, 2004, vol. 34, # 6, p. 1049 - 1056
[2] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 2, p. 355 - 360
[3] FEBS Journal, 2013, vol. 280, # 8, p. 1807 - 1817
[4] Tetrahedron Letters, 1993, vol. 34, # 28, p. 4493 - 4496
[5] Chemical Communications, 2013, vol. 49, # 29, p. 2977 - 2979

N-alpha-Cbz-L-2,4-diamiobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-alpha-Cbz-L-2,4-diamiobutyric acid Suppliers

China 116 Germany 4 India 2 Japan 2 Switzerland 2 United Kingdom 3 United States 13 Global 142
Carbosynth
Tel
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Fax
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Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Leancare Ltd.
Tel
--
Fax
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Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
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Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from N-alpha-Cbz-L-2,4-diamiobutyric acid manufacturers

Career Henan Chemical Co
Product
N-alpha-Cbz-L-2,4-diamiobutyric acid 62234-40-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-03

62234-40-6, N-alpha-Cbz-L-2,4-diamiobutyric acidRelated Search:

DL-2-Aminobutyric acid L(+)-2-Aminobutyric acid Folic acid Hyaluronic acid 4-Aminobutyric acid Ethyl 2-(Chlorosulfonyl)acetate DL-3-Aminobutyric acid N-Carbobenzyloxyglycine Citric acid α-Lipoic Acid Ascoric Acid r-Amino Butryric Acid 2-Aminobenzylchloride Z-ASN-ONP N-Benzyloxycarbonyl-L-asparagine Z-ASN(TRT)-OH N-alpha-Cbz-D-2-4-diaminobutanoic acid 2,4-DIAMINO-BUTYRIC ACID

  • N2-CBZ-(S)-2,4-DIAMINO-BUTANOIC ACID
  • N-ALPHA-Z-L-2,4-DIAMINOBUTYRIC ACID
  • n-alpha-cbz-l-2,4-diamiobutyric acid
  • N-ALPHA-CARBOBENZOXY-L-2,3-DIAMINOBUTYRIC ACID
  • N-ALPHA-CARBOBENZOXY-L-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
  • N-ALPHA-BENZYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID
  • Z-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
  • Z-DAB-OH
  • Z-L-DAB-OH
  • Z-L-2,4-DIAMINOBUTYRIC ACID
  • N-.ALPHA.-CBZ-D-2,4-DIAMINOBUTYRIC ACID
  • Nα-Z-L-2,4-diaminobutyric acid
  • Z-Dbu-OH
  • N-α-Z-D-2,4-diaminobutyric acid
  • Z-DAB-OH Z-L-2,4- DIAMINOBUTYRIC ACID
  • N-.ALPHA.-CBZ-L-2,4-DIAMINOBUTYRIC ACID
  • CBZ-DAB
  • Cbz-L-2,4-diaminobutyric acid
  • (S)-4-amino-2-(benzyloxycarbonylamino)butanoic acid
  • Z-Dab-OH(Na-Z-2,4-DiaMinobutyric acid)
  • N-α-Cbz-L-2,4-DiaMiobutyric acid
  • Nα-Z-L-2,4-diaminobutyric acid≥ 99% (HPLC)
  • (S)-4-Amino-2-(benzyloxycarbonylamino)butyric acid
  • Cbz-Dab-OH
  • N-Cbz-(S)-2,4-diamino-butanoic acids
  • Z-Dab-OH, ≥99.0% (sum of enantiomers, HPLC)
  • (2S)-4-amino-2-(phenylmethoxycarbonylamino)butanoic acid
  • (S)-4-Amino-2-(Cbz-amino)butanoic Acid
  • 4-amino-2-(phenylmethoxycarbonylamino)butanoic acid
  • Butanoic acid, 4-amino-2-[[(phenylmethoxy)carbonyl]amino]-, (2S)-
  • N-Alpha-Cbz-L-2,4-DiamiobutyricAci
  • N-alpha-Cbz-L-2,4-diamiobutyric acid USP/EP/BP
  • 62234-40-6
  • DAB (2,4-Diaminobutyric Acid)
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Specialty Synthesis
  • Amino Acid Derivatives