ChemicalBook > CAS DataBase List > HUMAN I-TAC
HUMAN I-TAC
Description Source Background- Product Name
- HUMAN I-TAC
- CAS No.
- 1927911-33-8
- Chemical Name
- HUMAN I-TAC
- Synonyms
- HUMAN B-R1;HUMAN H174;HUMAN I-TAC;HUMAN SCYB9B;HUMAN CXCL11;I-TAC (HUMAN);HUMAN BETA-R1;HUMAN ITAC (CXCL11);I-TAC/CXCL11, HUMAN;RECOMBINANT HUMAN I-TAC
- CBNumber
- CB1171266
- Formula Weight
- 0
- MOL File
- Mol file
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HUMAN I-TAC Property
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- human
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Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 26-36/37/39-45
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- I5528
- Product name
- Interferon-Inducible T Cell α Chemoattractant human
- Purity
- ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
- Packaging
- 25μG
- Price
- $447
- Updated
- 2025/07/31
Usbiological
- Product number
- I7662-19
- Product name
- Interferon-inducible T Cell Alpha Chemoattractant, Human
- Packaging
- 5ug
- Price
- $262
- Updated
- 2021/12/16
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HUMAN I-TAC Chemical Properties,Usage,Production
Biological Activity
I-TAC (Interferon-inducible T-cell α chemoattractant) is a chemokine which participates in recruitment of inflammatory cell. It binds to receptor CXCR3 (C-X-C motif chemokine receptor 3). I-TAC is associated with the severity of dengue.
Description
I-TAC Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 8300 Dalton.
The I-TAC is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokinen family that is also called inducible T-cell alpha chemoattractant (I-TAC) and (IP-9). I-TAC is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Gene expression of CXCL11 is strongly induced by IFN-g and IFN-b, and weakly induced by IFN-a. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
HUMAN I-TAC Preparation Products And Raw materials
Raw materials
Preparation Products
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