MEDICA 16
- Product Name
- MEDICA 16
- CAS No.
- 87272-20-6
- Chemical Name
- MEDICA 16
- Synonyms
- MEDICA 16;3,3,14,14-TETRAMETHYLHEXADECANEDIOIC ACID;3,3,14,14-TETRAMETHYLHEXADECANEDIONIC ACID;Hexadecanedioic acid, 3,3,14,14-tetramethyl-;ACLY,antidiabetogenic,ATP Citrate Lyase,antidiabetic,skeletal,Inhibitor,MEDICA16,ligands,Free Fatty Acid Receptor,MEDICA-16,insulin,FFAR,endogenous,muscle,inhibit
- CBNumber
- CB1175406
- Molecular Formula
- C20H38O4
- Formula Weight
- 342.51
- MOL File
- 87272-20-6.mol
MEDICA 16 Property
- Melting point:
- 154-159 °C
- Boiling point:
- 485.9±18.0 °C(Predicted)
- Density
- 0.984±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: 28 mg/mL
- form
- solid
- pka
- 4.51±0.10(Predicted)
- color
- white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- M5693
- Product name
- MEDICA 16
- Purity
- powder, ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $166
- Updated
- 2024/03/01
- Product number
- 90290
- Product name
- MEDICA 16
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 90290
- Product name
- MEDICA 16
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 90290
- Product name
- MEDICA 16
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $160
- Updated
- 2024/03/01
- Product number
- 90290
- Product name
- MEDICA 16
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $684
- Updated
- 2024/03/01
MEDICA 16 Chemical Properties,Usage,Production
Description
MEDICA 16 is a β,β''-
Uses
MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.
Uses
MEDICA 16 is a malic enzyme and mitochondrial glycerol-3-phosphate dehydrogenase inducer.
Definition
ChEBI: MEDICA 16 is an alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. It has a role as an antilipemic drug, an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor, an EC 2.3.3.8 (ATP citrate synthase) inhibitor, a G-protein-coupled receptor agonist and a hypoglycemic agent.
storage
-20°C
MEDICA 16 Preparation Products And Raw materials
Raw materials
Preparation Products
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