ChemicalBook > CAS DataBase List > MEDICA 16

MEDICA 16

Product Name
MEDICA 16
CAS No.
87272-20-6
Chemical Name
MEDICA 16
Synonyms
MEDICA 16;3,3,14,14-TETRAMETHYLHEXADECANEDIOIC ACID;3,3,14,14-TETRAMETHYLHEXADECANEDIONIC ACID;Hexadecanedioic acid, 3,3,14,14-tetramethyl-;ACLY,antidiabetogenic,ATP Citrate Lyase,antidiabetic,skeletal,Inhibitor,MEDICA16,ligands,Free Fatty Acid Receptor,MEDICA-16,insulin,FFAR,endogenous,muscle,inhibit
CBNumber
CB1175406
Molecular Formula
C20H38O4
Formula Weight
342.51
MOL File
87272-20-6.mol
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MEDICA 16 Property

Melting point:
154-159 °C
Boiling point:
485.9±18.0 °C(Predicted)
Density 
0.984±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: 28 mg/mL
form 
solid
pka
4.51±0.10(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M5693
Product name
MEDICA 16
Purity
powder, ≥97% (HPLC)
Packaging
5mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
90290
Product name
MEDICA 16
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
90290
Product name
MEDICA 16
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
90290
Product name
MEDICA 16
Purity
≥98%
Packaging
10mg
Price
$160
Updated
2024/03/01
Cayman Chemical
Product number
90290
Product name
MEDICA 16
Purity
≥98%
Packaging
50mg
Price
$684
Updated
2024/03/01
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MEDICA 16 Chemical Properties,Usage,Production

Description

MEDICA 16 is a β,β''-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.

Uses

MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.

Uses

MEDICA 16 is a malic enzyme and mitochondrial glycerol-3-phosphate dehydrogenase inducer.

Definition

ChEBI: MEDICA 16 is an alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. It has a role as an antilipemic drug, an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor, an EC 2.3.3.8 (ATP citrate synthase) inhibitor, a G-protein-coupled receptor agonist and a hypoglycemic agent.

storage

-20°C

MEDICA 16 Preparation Products And Raw materials

Raw materials

Preparation Products

87272-20-6, MEDICA 16Related Search:


  • MEDICA 16
  • 3,3,14,14-TETRAMETHYLHEXADECANEDIOIC ACID
  • 3,3,14,14-TETRAMETHYLHEXADECANEDIONIC ACID
  • Hexadecanedioic acid, 3,3,14,14-tetramethyl-
  • ACLY,antidiabetogenic,ATP Citrate Lyase,antidiabetic,skeletal,Inhibitor,MEDICA16,ligands,Free Fatty Acid Receptor,MEDICA-16,insulin,FFAR,endogenous,muscle,inhibit
  • 87272-20-6
  • Biochemicals and Reagents
  • BioChemical
  • A to C
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Citrate Lyase