N-HYDROXYPROPIONAMIDINE

Product Name: N-HYDROXYPROPIONAMIDINE
CAS No.: 29335-36-2
Chemical Name: N-HYDROXYPROPIONAMIDINE
Synonyms: Propionamidoxime;AKOS B030359;N-HYDROXYPROPIONAMIDINE;N'-hydroxypropaniMidaMide;N-HydroxypropioniMidaMide;(E)-N'-Hydroxypropimidamide;PropaniMidaMide, N-hydroxy-;(E)-N'-hydroxypropionimidamide;(1Z)-N'-hydroxypropanimidamide 1HCl;propanimidamide, N'-hydroxy-, (1Z)-
CBNumber: CB1176256
Molecular Formula: C3H8N2O
Formula Weight: 88.11
MOL File: 29335-36-2.mol

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N-HYDROXYPROPIONAMIDINE Property

Boiling point:: 132.8±23.0 °C(Predicted)
Density: 1.12±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 7.48±0.69(Predicted)
Appearance: Colorless to off-white Viscous Liquid
Water Solubility: Slightly soluble in water.
Sensitive: Hygroscopic
CAS DataBase Reference: 29335-36-2

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Safety

Hazard Codes: T
Risk Statements: 36/37/38-25
Safety Statements: 26-36/37/39-45
RIDADR: UN3267
HazardClass: 8
PackingGroup: III
HS Code: 2925290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: E555820
Product name: (E)-N''-hydroxypropionimidamide
Packaging: 500mg
Price: $265
Updated: 2021/12/16

BroadPharm

Product number: BP-21173
Product name: (1Z)-N'-HYDROXYPROPANIMIDAMIDE
Packaging: 250mg
Price: $35
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4147-5-06
Product name: N-Hydroxypropanimidamide hydrochloride
Packaging: 1g
Price: $184
Updated: 2021/12/16

Matrix Scientific

Product number: 132104
Product name: N-Hydroxypropionamidine
Purity: 97%
Packaging: 1g
Price: $396
Updated: 2021/12/16

AK Scientific

Product number: 9295AD
Product name: (1Z)-N'-Hydroxypropanimidamidehydrochloride
Packaging: 5g
Price: $435
Updated: 2021/12/16

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N-HYDROXYPROPIONAMIDINE Chemical Properties,Usage,Production

Uses

Propionamidoxime is used as pharmaceutical intermediate.

Synthesis

107-12-0

29335-36-2

The general procedure for the synthesis of N-hydroxypropionic acid amidine from propionitrile was as follows: hydroxylamine hydrochloride (18.9 g, 272.7 mmol) and anhydrous potassium carbonate (37.6 g, 272.7 mmol) were suspended in a mixed solvent of ethanol/water (200 mL/50 mL), and stirred for 1 h at room temperature. Subsequently, propionitrile (10.0 g, 181.8 mmol) was added to the reaction system. The reaction mixture was heated to reflux and stirred continuously for 20 h. The reaction process was monitored by thin layer chromatography (unfolding agent: dichloromethane/methanol, 50/1 volume ratio). Upon completion of the reaction, the inorganic salts were removed by filtration and the filtrate was concentrated under reduced pressure to afford N-hydroxypropionic acid amidine (13.5 g, 81% yield) as a light yellow solid.

References

[1] Patent: CN104513235, 2017, B. Location in patent: Paragraph 1308; 1309
[2] Chemische Berichte, 1884, vol. 17, p. 2753
[3] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1957, vol. 245, p. 419,420
[4] Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1966, vol. 262, p. 592 - 595
[5] Monatshefte fuer Chemie, 1982, vol. 113, p. 781 - 792

N-HYDROXYPROPIONAMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-HYDROXYPROPIONAMIDINE Suppliers

China 69 Germany 2 India 2 United Kingdom 2 United States 12 Global 87

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View Lastest Price from N-HYDROXYPROPIONAMIDINE manufacturers

Career Henan Chemical Co

Product: N-HYDROXYPROPIONAMIDINE 29335-36-2
Price: US $1.00/KG
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-10

29335-36-2, N-HYDROXYPROPIONAMIDINERelated Search:

N-HYDROXYPROPIONAMIDINE (1E)-N'-HYDROXY-2-PHENYLETHANIMIDAMIDE N'-Hydroxycyclopropanecarboximidamide N'-Hydroxy-2-methylpropanimidamide 1-Pyrrolidineethanimidamide, N-hydroxy-alpha-methyl-2-oxo-4-phenyl- N-HYDROXY-2-(4-HYDROXY-PHENYL)-ACETAMIDINE N-HYDROXY-2,2-DIMETHYLPROPANIMIDAMIDE N-HYDROXYCYCLOPENTANECARBOXIMIDAMIDE 2-(4-BROMO-PHENYL)-N-HYDROXY-ACETAMIDINE (3Z)-3-AMINO-N-(3-CHLORO-4-METHYLPHENYL)-3-(HYDROXYIMINO)PROPANAMIDE 2-(3,4-DIMETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE 1400W N-HYDROXYCYCLOBUTANECARBOXIMIDAMIDE N-HYDROXY-3-OXO-3-PYRROLIDIN-1-YLPROPANIMIDAMIDE 3-CHLORO-N-HYDROXY-PROPANIMIDAMIDE N-HYDROXY-4-(1-PYRROLIDINE)-BUTYRAMIDINE 1-NITROPENTANENITRONATE 2-BENZOYL-4,4-DIMETHYL-5-PHENYL-4H-IMIDAZOLE 1-OXIDE

AKOS B030359

N-HYDROXYPROPIONAMIDINE

Propionamidoxime

(1Z)-N'-hydroxypropanimidamide hydrochloride

propanimidamide, N'-hydroxy-, (1Z)-

N'-hydroxypropaniMidaMide

PropaniMidaMide, N-hydroxy-

N-HydroxypropioniMidaMide

(E)-N'-Hydroxypropimidamide

(1Z)-N'-hydroxypropanimidamide(SALTDATA: HCl)

(1Z)-N'-hydroxypropanimidamide 1HCl

N-Hydroxypropanimidamide hydrochloride

(E)-N'-hydroxypropionimidamide

29335-36-2

pharmacetical