1400W

Product Name: 1400W
CAS No.: 180001-34-7
Chemical Name: 1400W
Synonyms: 1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
CBNumber: CB5343313
Molecular Formula: C10H15N3
Formula Weight: 177.25
MOL File: 180001-34-7.mol

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1400W Property

Melting point:: 208-220 °C
Boiling point:: 301.7±44.0 °C(Predicted)
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO, Methanol, Water
pka: 11.33±0.50(Predicted)
form: solid
color: White to Off-White

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1415
Product name: 1400W dihydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $125
Updated: 2021/12/16

Tocris

Product number: 1415
Product name: 1400W dihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $526
Updated: 2021/12/16

TRC

Product number: W400050
Product name: W1400
Packaging: 1mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 044436
Product name: 1400W dihydrochloride
Packaging: 5mg
Price: $282
Updated: 2021/12/16

Usbiological

Product number: 169589
Product name: 1400W Dihydrochloride
Packaging: 5mg
Price: $286
Updated: 2021/12/16

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1400W Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Definition

ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

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1400W Suppliers

Canada 1 China 35 Europe 1 France 1 Germany 3 Japan 3 Switzerland 3 United Kingdom 6 United States 8 Global 61

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Ascent Scientific

Tel: 4401179829988
Fax: 4402030 700 369
Email: customerservice@ascentscientific.co.uk
Country: United Kingdom
ProdList: 279
Advantage: 60

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 647
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1832
Advantage: 55

Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10523
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 15093356674;
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29826
Advantage: 58

Shanghai Zeye Biotechnology Co., Ltd.

Tel: 021-61998551 13122364865
Email: sale1@shzysw.net
Country: China
ProdList: 9763
Advantage: 58

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View Lastest Price from 1400W manufacturers

Career Henan Chemical Co

Product: 400W 180001-34-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

180001-34-7, 1400WRelated Search:

METHACRYLOXYPROPYLTRIS(TRIMETHYLSILOXY)SILANE: 6% DIMER SIB1400 Recombinant Hepatitis C Virus NS3 (1400-1643) POLYETHYLENEIMINE BRL-1400 Hydrate POLYCARBOMETHYLSILANE MW 1400 NC 1400 VITAMIN E(D-ALPHA TYPE) NATURAL 1000-1400IU Raltitrexed Alcian Blue pyridine variant Aspartate aminotransferase Sodium polystyrene sulfonate PANCREATIN ,1400 FIP-U G PROTEASE 24000 FIP-U G LIPASE 30000 FIP-U G AMYLASE PH EUR,4 X USP Poly(tetrahydrofuran) 2-Hydroxypropyl-β-cyclodextrin Quartz Poly(ethylene glycol-ran-propylene glycol) monobutyl ether POLYDIPHENYLSILOXANE, SILANOL TERMINATED, GLASSY SOLID, M.W. 1000-1400 TERT-BUTYL N-[3-(ACETIMIDOYLAMINOMETHYL)BENZYL]CARBAMATE, HYDROCHLORIDE

1400W

1400W DIHYDROCHLORIDE

N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE

400W

W 1400

Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-

N-(3-(aminomethyl)benzyl)acetimidamide

180001-34-7

18001-34-7

Biochemicals and Reagents

BioChemical

Application Index

Cell Signaling Enzymes

NOS Inhibitors

Enzymes, Inhibitors, and Substrates

Nitric Oxide Metabolism

Nitric Oxide Reagents

Nitric Oxide

Aromatic Building Blocks

Signalling