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1400W

Product Name
1400W
CAS No.
180001-34-7
Chemical Name
1400W
Synonyms
1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
CBNumber
CB5343313
Molecular Formula
C10H15N3
Formula Weight
177.25
MOL File
180001-34-7.mol
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1400W Property

Melting point:
208-220 °C
Boiling point:
301.7±44.0 °C(Predicted)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO, Methanol, Water
pka
11.33±0.50(Predicted)
form 
solid
color 
White to Off-White
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1415
Product name
1400W dihydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$125
Updated
2021/12/16
Tocris
Product number
1415
Product name
1400W dihydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$526
Updated
2021/12/16
TRC
Product number
W400050
Product name
W1400
Packaging
1mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
044436
Product name
1400W dihydrochloride
Packaging
5mg
Price
$282
Updated
2021/12/16
Usbiological
Product number
169589
Product name
1400W Dihydrochloride
Packaging
5mg
Price
$286
Updated
2021/12/16
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1400W Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Definition

ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

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1400W Suppliers

Nacalai Tesque, Inc.
Tel
--
Fax
--
Email
info-tech@nacalai.co.jp
Country
Japan
ProdList
6046
Advantage
75
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from 1400W manufacturers

Career Henan Chemical Co
Product
400W 180001-34-7
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

180001-34-7, 1400WRelated Search:


  • 1400W
  • 1400W DIHYDROCHLORIDE
  • N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE
  • 400W
  • W 1400
  • Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-
  • N-(3-(aminomethyl)benzyl)acetimidamide
  • 180001-34-7
  • 18001-34-7
  • Biochemicals and Reagents
  • BioChemical
  • Application Index
  • Cell Signaling Enzymes
  • NOS Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide Metabolism
  • Nitric Oxide Reagents
  • Nitric Oxide
  • Aromatic Building Blocks
  • Signalling