1400W
- Product Name
- 1400W
- CAS No.
- 180001-34-7
- Chemical Name
- 1400W
- Synonyms
- 1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
- CBNumber
- CB5343313
- Molecular Formula
- C10H15N3
- Formula Weight
- 177.25
- MOL File
- 180001-34-7.mol
1400W Property
- Melting point:
- 208-220 °C
- Boiling point:
- 301.7±44.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO, Methanol, Water
- pka
- 11.33±0.50(Predicted)
- form
- solid
- color
- White to Off-White
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 1415
- Product name
- 1400W dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 1415
- Product name
- 1400W dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $526
- Updated
- 2021/12/16
- Product number
- W400050
- Product name
- W1400
- Packaging
- 1mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 044436
- Product name
- 1400W dihydrochloride
- Packaging
- 5mg
- Price
- $282
- Updated
- 2021/12/16
- Product number
- 169589
- Product name
- 1400W Dihydrochloride
- Packaging
- 5mg
- Price
- $286
- Updated
- 2021/12/16
1400W Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM
Uses
1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.
Definition
ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.
Biological Activity
Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .
1400W Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from 1400W manufacturers
- Product
- 400W 180001-34-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-25