ChemicalBook > CAS DataBase List > 1400W

1400W

Product Name
1400W
CAS No.
180001-34-7
Chemical Name
1400W
Synonyms
1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
CBNumber
CB5343313
Molecular Formula
C10H15N3
Formula Weight
177.25
MOL File
180001-34-7.mol
More
Less

1400W Property

Melting point:
208-220 °C
Boiling point:
301.7±44.0 °C(Predicted)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO, Methanol, Water
pka
11.33±0.50(Predicted)
form 
solid
color 
White to Off-White
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1415
Product name
1400W dihydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$125
Updated
2021/12/16
Tocris
Product number
1415
Product name
1400W dihydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$526
Updated
2021/12/16
TRC
Product number
W400050
Product name
W1400
Packaging
1mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
044436
Product name
1400W dihydrochloride
Packaging
5mg
Price
$282
Updated
2021/12/16
Usbiological
Product number
169589
Product name
1400W Dihydrochloride
Packaging
5mg
Price
$286
Updated
2021/12/16
More
Less

1400W Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Definition

ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

in vivo

1400W (0.1-10 mg/kg, s.c., once time) inhibits the leakage of rats ileum, with an EC50 of 0.16 mg/kg[1].

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1400W Suppliers

Canada 1 China 46 Europe 1 France 1 Germany 3 Japan 3 Switzerland 3 United Kingdom 6 United States 9 Global 73
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Guangzhou Zhiya Chemdrugs Co.,Ltd
Tel
18122150900
Fax
QQ:2869377561
Email
sculk28@163.com
Country
China
ProdList
646
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1944
Advantage
55
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-021-61998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
9778
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
15921930842 15921930842
Email
yh-wang@univ-bio.com
Country
China
ProdList
25004
Advantage
58
Shanghai Tachizaki Biomedical Research Center
Tel
18014399201
Email
sales@chemlab-tachizaki.com
Country
China
ProdList
2742
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29423
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
029-81136151 17392212881
Email
1095@dideu.com
Country
China
ProdList
10001
Advantage
58
Adipogen Life Sciences
Tel
41-6192660-40
Email
info@adipogen.com
Country
China
ProdList
5293
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Aikon International Limited
Tel
025-58851090 13408877820
Email
2850281427@qq.com
Country
China
ProdList
10000
Advantage
58
Hebei Yaocheng Pharmaceutical Technology Co. Ltd
Tel
18033875090
Email
yc-eliu@yaochengph.com
Country
China
ProdList
5488
Advantage
58
Zibo Hangyu Biotechnology Development Co., Ltd
Tel
+86-0533-2185556 +8615965530500
Email
nickzhang@hangyubiotech.com
Country
China
ProdList
8510
Advantage
58
Guangzhou Yiran Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
ProdList
141
Advantage
58
Guangzhou Meijun Biotechnology Co., Ltd.
Tel
18664742264
Country
CHINA
ProdList
151
Advantage
58
Guangzhou Junuo Biotechnology Co., Ltd.
Tel
13432975901
Country
CHINA
ProdList
132
Advantage
58
Hangzhou Yuyang Biotechnology Co., Ltd.
Tel
13454179135
Country
CHINA
ProdList
161
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Shanghai Xiyuan Biotechnology Co., Ltd
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6934
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Beijing Dongge Boye Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1861586486@qq.com
Country
CHINA
ProdList
6648
Advantage
58
Changzhou Beiyuanxin Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
4375
Advantage
58
Nanjing Sai Ruirui Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
sales@shrbio.com
Country
CHINA
ProdList
6666
Advantage
58
Shanghai Yuda Industrial Co., Ltd.
Tel
--
Fax
--
Email
lucy@runwelltac.com
Country
CHINA
ProdList
6448
Advantage
58
Shanghai Yuqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
847627550@qq.com
Country
CHINA
ProdList
6087
Advantage
58
Shanghai Jingke Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jingkehuaxue@163.com
Country
CHINA
ProdList
6141
Advantage
58
Beijing Anbiqi Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@abace-biology.com
Country
CHINA
ProdList
2529
Advantage
58
Shenzhen Branch Science and Technology Co., Ltd.
Tel
--
Fax
--
Email
zikerbio@163.com
Country
CHINA
ProdList
6374
Advantage
58
Beijing Zhijie Fangyuan Technology Co., Ltd.
Tel
--
Fax
--
Email
15810200961@163.com
Country
CHINA
ProdList
6643
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Shanghai Boyi Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
15800446246@163.com
Country
CHINA
ProdList
5416
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
--
Fax
--
Email
kexianxun@gmail.com
Country
China
ProdList
1037
Advantage
50
Qiyi Biotechnology (Shanghai) Co., Ltd.
Tel
--
Fax
--
Email
qiyibio@163.com
Country
CHINA
ProdList
6241
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6170
Advantage
58
Shanghai Yupu Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
2439781853@qq.com
Country
CHINA
ProdList
1328
Advantage
58
Wuhan Boot Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6829
Advantage
58
Express Technology Co., Ltd.
Tel
--
Fax
--
Email
2542800150@qq.com
Country
China
ProdList
115
Advantage
30
Beijing Seajet Scientific Inc
Tel
--
Fax
--
Email
info@seajetsci.com
Country
China
ProdList
377
Advantage
70
Advanced Technology & Industrial Co., Ltd.
Tel
--
Fax
--
Email
sales@advtechind.com
Country
China
ProdList
6523
Advantage
75
More
Less

View Lastest Price from 1400W manufacturers

Career Henan Chemical Co
Product
400W 180001-34-7
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

180001-34-7, 1400WRelated Search:

METHACRYLOXYPROPYLTRIS(TRIMETHYLSILOXY)SILANE: 6% DIMER SIB1400 Recombinant Hepatitis C Virus NS3 (1400-1643) POLYETHYLENEIMINE BRL-1400 Hydrate POLYCARBOMETHYLSILANE MW 1400 NC 1400 VITAMIN E(D-ALPHA TYPE) NATURAL 1000-1400IU Raltitrexed Alcian Blue pyridine variant Aspartate aminotransferase Sodium polystyrene sulfonate PANCREATIN ,1400 FIP-U G PROTEASE 24000 FIP-U G LIPASE 30000 FIP-U G AMYLASE PH EUR,4 X USP Poly(tetrahydrofuran) 2-Hydroxypropyl-β-cyclodextrin Poly(ethylene glycol-ran-propylene glycol) monobutyl ether POLYDIPHENYLSILOXANE, SILANOL TERMINATED, GLASSY SOLID, M.W. 1000-1400 Quartz TERT-BUTYL N-[3-(ACETIMIDOYLAMINOMETHYL)BENZYL]CARBAMATE, HYDROCHLORIDE

  • 1400W
  • 1400W DIHYDROCHLORIDE
  • N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL
  • N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE
  • 400W
  • W 1400
  • Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-
  • N-(3-(aminomethyl)benzyl)acetimidamide
  • 180001-34-7
  • 18001-34-7
  • Biochemicals and Reagents
  • BioChemical
  • Application Index
  • Cell Signaling Enzymes
  • NOS Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide Metabolism
  • Nitric Oxide Reagents
  • Nitric Oxide
  • Aromatic Building Blocks
  • Signalling