1400W

Product Name: 1400W
CAS No.: 180001-34-7
Chemical Name: 1400W
Synonyms: 1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
CBNumber: CB5343313
Molecular Formula: C10H15N3
Formula Weight: 177.25
MOL File: 180001-34-7.mol

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1400W Property

Melting point:: 208-220 °C
Boiling point:: 301.7±44.0 °C(Predicted)
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO, Methanol, Water
pka: 11.33±0.50(Predicted)
form: solid
color: White to Off-White

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1415
Product name: 1400W dihydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $125
Updated: 2021/12/16

Tocris

Product number: 1415
Product name: 1400W dihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $526
Updated: 2021/12/16

TRC

Product number: W400050
Product name: W1400
Packaging: 1mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 044436
Product name: 1400W dihydrochloride
Packaging: 5mg
Price: $282
Updated: 2021/12/16

Usbiological

Product number: 169589
Product name: 1400W Dihydrochloride
Packaging: 5mg
Price: $286
Updated: 2021/12/16

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1400W Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Definition

ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

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1400W Suppliers

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View Lastest Price from 1400W manufacturers

Career Henan Chemical Co

Product: 400W 180001-34-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

180001-34-7, 1400WRelated Search:

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1400W

1400W DIHYDROCHLORIDE

N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL

N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE

400W

W 1400

Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-

N-(3-(aminomethyl)benzyl)acetimidamide

180001-34-7

18001-34-7

Biochemicals and Reagents

BioChemical

Application Index

Cell Signaling Enzymes

NOS Inhibitors

Enzymes, Inhibitors, and Substrates

Nitric Oxide Metabolism

Nitric Oxide Reagents

Nitric Oxide

Aromatic Building Blocks

Signalling