2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE

Product Name: 2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE
CAS No.: 51486-03-4
Chemical Name: 2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE
Synonyms: AKOS MSC-0460;2-AMino-5-Methyl-3-thiophenecarboxaMid;2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE;2-AMINO-5-METHYLTHIOPHENE-3-CARBOXAMIDE;3-Thiophenecarboxamide, 2-amino-5-methyl-;2-AMino-5-Methyl-thiophene-3-carboxylic acid aMide
CBNumber: CB1182802
Molecular Formula: C6H8N2OS
Formula Weight: 156.21
MOL File: 51486-03-4.mol

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2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE Property

Boiling point:: 274℃
Density: 1.344
Flash point:: 120℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
Appearance: Light brown to brown Solid

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Safety

RIDADR: UN 2811 6.1 / PGIII

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: OTV000759
Product name: 2-Amino-5-methylthiophene-3-carboxamide
Packaging: 1g
Price: $259
Updated: 2025/07/31

TRC

Product number: A619875
Product name: 2-amino-5-methylthiophene-3-carboxamide
Packaging: 25mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A619875
Product name: 2-amino-5-methylthiophene-3-carboxamide
Packaging: 50mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 4696AE
Product name: 2-Amino-5-methylthiophene-3-carboxamide
Packaging: 5g
Price: $320
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0310382
Product name: 2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $500.03
Updated: 2021/12/16

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2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE Chemical Properties,Usage,Production

Synthesis

138564-58-6

51486-03-4

Example 8: Synthesis of N-(3-hydroxyphenethyl)-2,6-dimethylthieno[2,3-d]pyrimidin-4-amine (final compound 22). a) Preparation of 2-amino-5-methylthiophene-3-carboxamide; according to Scheme 5 Step 1: 2-amino-5-methylthiophene-3-carbonitrile (4.00 g, 28.9 mmol) was dissolved in concentrated sulphuric acid (38.8 ml), and the reaction was stirred for 20 hours at room temperature. Upon completion of the reaction, the mixture was slowly poured into ice water (250 g) and the pH was adjusted with concentrated sodium hydroxide solution to 7. Subsequently, the mixture was extracted with ethyl acetate, the organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (Flashmart Pack: 85g / 60-40um, eluent: ethyl acetate) to afford 2-amino-5-methyl-3-thiophenecarboxamide (3.10g, 69% yield) as a brown solid.

References

[1] Patent: WO2006/30031, 2006, A1. Location in patent: Page/Page column 57

2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE Suppliers

China 29 Europe 1 Germany 1 India 1 Russia 1 Switzerland 1 United Kingdom 3 United States 7 Global 44

skychemical Co.Ltd

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Sigma-Aldrich

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51486-03-4, 2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDERelated Search:

2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXAMIDE ETHYL 5-METHYL-4-OXO-3,4-DIHYDROTHIENO[2,3-D]-PYRIMIDINE-6-CARBOXYLATE (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE AKOS 94123 2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE 2-(2-CHLORO-ACETYLAMINO)-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID AMIDE AKOS BBS-00007188 7-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-[(2,4-DICHLOROBENZYL)SULFANYL]-3-METHYL-5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5]THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE 3-CYCLOHEXYL-2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE AKOS 90535 3-ETHYL-2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE 7-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-METHYL-2-SULFANYL-5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5]THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE 2-methyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one BUTTPARK 25\07-05 AKOS BBS-00007201 AKOS 93050 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE

2-AMINO-5-METHYLTHIOPHENE-3-CARBOXAMIDE

2-AMINO-5-METHYL-3-THIOPHENECARBOXAMIDE

AKOS MSC-0460

2-AMino-5-Methyl-3-thiophenecarboxaMid

3-Thiophenecarboxamide, 2-amino-5-methyl-

2-AMino-5-Methyl-thiophene-3-carboxylic acid aMide

51486-03-4