2,4-DIHYDROXY-6-METHYLBENZOIC ACID

ChemicalBook > CAS DataBase List > 2,4-DIHYDROXY-6-METHYLBENZOIC ACID

2,4-DIHYDROXY-6-METHYLBENZOIC ACID

Product Name: 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
CAS No.: 480-64-8
Chemical Name: 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
Synonyms: 133346;Orsellic acid;o-orsellinicaci;ORSELLINIC ACID;o-orsellinic acid;ORSELLINIC ACID MONOHYDRATE;2,4-DIHYDROXY-6-METHYLBENZOIC ACID;6-Methyl-2,4-dihydroxybenzoic acid;2-Methyl-4,6-dihydroxybenzoic acid;Benzoic acid, 2,4-dihydroxy-6-Methyl-
CBNumber: CB1185500
Molecular Formula: C8H8O4
Formula Weight: 168.15
MOL File: 480-64-8.mol

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2,4-DIHYDROXY-6-METHYLBENZOIC ACID Property

Melting point:: 173-174°C
Boiling point:: 257.07°C (rough estimate)
Density: 1.3037 (rough estimate)
refractive index: 1.5090 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: pK (25°) 3.90
color: White to Pale Gray
Water Solubility: Soluble in water, dimethyl sulfoxide or 100% ethanol.
Stability:: Hygroscopic
CAS DataBase Reference: 480-64-8

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22708
Product name: Orsellinic Acid
Purity: ≥98%
Packaging: 10mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 22708
Product name: Orsellinic Acid
Purity: ≥98%
Packaging: 50mg
Price: $225
Updated: 2024/03/01

Cayman Chemical

Product number: 22708
Product name: Orsellinic Acid
Purity: ≥98%
Packaging: 100mg
Price: $337
Updated: 2024/03/01

Cayman Chemical

Product number: 22708
Product name: Orsellinic Acid
Purity: ≥98%
Packaging: 250mg
Price: $632
Updated: 2024/03/01

Usbiological

Product number: 461634
Product name: Orsellinic Acid
Packaging: 1mg
Price: $403
Updated: 2021/12/16

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2,4-DIHYDROXY-6-METHYLBENZOIC ACID Chemical Properties,Usage,Production

Description

Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC₅₀ value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr^-/-) mouse cerebellar granule cells.

Uses

Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.

Definition

ChEBI: A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group.

Biosynthesis

One of the simplest polyketide derivatives, orsellinic acid is widely distributed in fungi. It is biosynthesised from an acetate starter unit and three malonyl units, as shown in Figure. Intramolecular condensation of the polyketide chain gives orsellinic acid without further modification.

The biosynthesis of orsellinic acid.

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 3566, 1965 DOI: 10.1021/jo01021a507

2,4-DIHYDROXY-6-METHYLBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 2,4-dihydroxy-6-methylbenzoate

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View Lastest Price from 2,4-DIHYDROXY-6-METHYLBENZOIC ACID manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2,4-DIHYDROXY-6-METHYLBENZOIC ACID 480-64-8
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-29

Career Henan Chemical Co

Product: 2,4-DIHYDROXY-6-METHYLBENZOIC ACID 480-64-8
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-08

480-64-8, 2,4-DIHYDROXY-6-METHYLBENZOIC ACIDRelated Search:

Mycophenolic acid Zearalenone Ethyl 2,4-dihydroxy-6-methylbenzoate BETA-ZEARALANOL 3-Formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester ETHYL 3,5-DIBROMO-2,4-DIHYDROXY-6-METHYLBENZOATE FUMARPROTOCETRARIC ACID 3,5-Dibromo-2,4-dihydroxy-6-methylbenzoic acid methyl ester METHYL 2,4-DIMETHOXY-6-METHYLBENZOATE EVERNIC ACID PSOROMIC ACID METHYL 3,5-DIBROMO-2,4-DIMETHOXY-6-METHYLBENZOATE ZERANOL METHYL 2,4-DIHYDROXY-3-METHYLBENZOATE DIHYDROXY-4-METHYLBENZOIC ACID,3,5-(RG),3,5-DIHYDROXY-4-METHYLBENZOIC ACID,DIHYDROXY-4-METHYLBENZOIC ACID,3,5- 3-Formyl-2,4-dihydroxy-6-methylbenzoic acid (2-carboxy-4-formyl-3,5-dihydroxyphenyl)methyl ester STICTIC ACID ZEARALANONE

2,4-DIHYDROXY-6-METHYLBENZOIC ACID

ORSELLINIC ACID

ORSELLINIC ACID MONOHYDRATE

2,4-Dihydroxy-6-methylbenzoic acid hydrate, 97%

2-Methyl-4,6-dihydroxybenzoic acid

6-Methyl-2,4-dihydroxybenzoic acid

Orsellic acid

o-orsellinic acid

Benzoic acid, 2,4-dihydroxy-6-Methyl-

133346

o-orsellinicaci

480-64-8

Inhibitors

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts