ANTI-CD1A
- Product Name
- ANTI-CD1A
- Chemical Name
- ANTI-CD1A
- Synonyms
- Anti-R7;Anti-CD1;ANTI-CD1A;Anti-BDCA1;ANTI-HUMAN T6;Anti-a1 domain;ANTI-HUMAN CDIA;ANTI-HUMAN CD1A;ANTI-CD1A, HUMAN;Anti-CD1c molecule
- CBNumber
- CB1188495
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-CD1A Property
- storage temp.
- -20°C
- form
- buffered aqueous solution
- biological source
- rabbit
N-Bromosuccinimide Price
- Product number
- WH0000911M2
- Product name
- Monoclonal Anti-CD1C antibody produced in mouse
- Purity
- clone 4B11, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- WH0000909M1
- Product name
- Monoclonal Anti-CD1A antibody produced in mouse
- Purity
- clone M1-2-1B5, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100 μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- SAB4700903
- Product name
- Monoclonal Anti-CD1c antibody produced in mouse
- Purity
- clone L161
- Packaging
- 100μG
- Price
- $433
- Updated
- 2025/07/31
- Product number
- SAB4700028
- Product name
- Monoclonal Anti-CD1A antibody produced in mouse
- Purity
- clone HI149, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100 μg
- Price
- $218
- Updated
- 2025/07/31
- Product number
- SAB1105750
- Product name
- Anti-CD1C (96-110) antibody produced in rabbit
- Purity
- IgG fraction of antiserum
- Packaging
- 200μL
- Price
- $436
- Updated
- 2025/07/31
ANTI-CD1A Chemical Properties,Usage,Production
Uses
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
General Description
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. (provided by RefSeq)
Biological Activity
CD1 (cluster of differentiation 1) family of proteins is responsible for the capture and presentation of self and microbial glycolipids to the specific T cells. CD1A plays an important role in the host defense mechanism against microbial infection. It also facilitates early stages of immune response through CD1A-reactive T cells. This is achieved by inducing cytokine production and dendritic cell maturation, and activating cells such as NK (natural killer) cells and macrophages. The SNP rs411089, present in an intron in the CD1A gene is associated with increased susceptibility to tuberculosis, in Vietnamese population. Hence, it can be hypothesized th at CD1A plays an important role in host defense against tuberculosis. The expression of this protein is also increased in monocyte culture derived from untreated multiple sclerosis (MS) patients, as opposed to expression in monocyte culture obtained from treated MS patients.
ANTI-CD1A Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CD1A Suppliers
- Tel
- 021-57763112 13585886131
- 3004987436@qq.com
- Country
- China
- ProdList
- 9692
- Advantage
- 58
- Tel
- 18818239863
- 3171921642@qq.com
- Country
- China
- ProdList
- 9260
- Advantage
- 58
- Tel
- 46-854595850
- order@atlasantibodies.com
- Country
- China
- ProdList
- 6586
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58