Dodecyl aldehyde Property

Melting point:

12 °C

Boiling point:

185 °C/100 mmHg (lit.)

Density 

0.831 g/mL at 25 °C (lit.)

vapor pressure 

<300 hPa (50 °C)

FEMA 

2615 | LAURIC ALDEHYDE

refractive index 

n20/D 1.435(lit.)

Flash point:

215 °F

storage temp. 

Store at +2°C to +8°C.

solubility 

soluble in Chloroform, Methanol

color 

White or Colorless to Light yellow

Odor

at 10.00 % in dipropylene glycol. soapy waxy aldehydic citrus green floral

Odor Type

aldehydic

Water Solubility 

Insoluble

JECFA Number

110

BRN 

1703917

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents, strong bases.

LogP

4.9 at 35℃

CAS DataBase Reference

112-54-9(CAS DataBase Reference)

NIST Chemistry Reference

Dodecanal(112-54-9)

EPA Substance Registry System

Dodecanal (112-54-9)

Safety

Hazard Codes 

Xi,N

Risk Statements 

36/37/38-51/53-38

Safety Statements 

26-36-61-37-29

RIDADR 

UN 3082 9 / PGIII

WGK Germany 

2

RTECS 

JR1910000

F 

10-23

Autoignition Temperature

200 °C

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29121900

Toxicity

LD50 orally in Rabbit: 23000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Dodecyl aldehyde Chemical Properties,Usage,Production

Chemical Properties

Dodecanal is a colorless liquid with a waxy odor; in high dilution, it is reminiscent of violets. Dodecanal occurs in several citrus oils and has been found in small amounts in essential oils obtained from several Pinus species. It is used in perfumery in conifer fragrances with fatty, waxy notes, but also in many other odor types. It is added to aroma compositions to obtain citrus notes.

Chemical Properties

Lauric aldehyde has a characteristic fatty odor reminiscent of violet on dilution and a fatty, woody taste.

Chemical Properties

colourless liquid

Occurrence

Reported found in the essential oils of lemon, sweet orange, bitter orange, mandarin, Mexican lime and petitgrain bigarade and in the turpentine of some varieties of pine. Also reported found in berries, apple, carrot, celery, cucumber, rutabaga, ginger, wheat bread, cheeses, milk, butter, caviar, fatty fish, roast chicken, cooked beef and pork, hop oil, beer, rum, peanut, mango, kelp, coriander seed and leaf, lovage leaf, buckwheat, cherimoya, mountain papaya, clam, scallop, loganberry and mate.

Uses

Dodecyl aldehyde is used as a fragrance agent. It is used as a common ingredient in perfumery. It's end applications include soap, detergent, beauty care product, household product.

Uses

Dodecanal is a fragrance agent that is found in soaps, perfumes as well as in food flavoring materials.

Preparation

By oxidation of the corresponding alcohol or reduction of the acid

Definition

ChEBI: Dodecanal is a long-chain fatty aldehyde that is dodecane in which two hydrogens attached to a terminal carbon are replaced by an oxo group. It has a role as a plant metabolite. It is a 2,3-saturated fatty aldehyde, a medium-chain fatty aldehyde and a long-chain fatty aldehyde. It derives from a hydride of a dodecane.

Aroma threshold values

Detection: 0.5 to 1.5 ppb; aroma characteristics at 2.0%: soapy, waxy, aldehydic, citrus, orange rindy with floral nuances

Taste threshold values

Taste characteristics at 2.0 ppm: soapy, waxy, citrus, orange mandarin.

Synthesis Reference(s)

Chemistry Letters, 11, p. 1081, 1982
Journal of the American Chemical Society, 99, p. 7365, 1977 DOI: 10.1021/ja00464a051
Tetrahedron Letters, 17, p. 2503, 1976

General Description

Lauric aldehyde is one of the main aliphatic green volatile compounds in macerated grape cluster stems. It is also one of the key flavor constituents of grapefruit oil.

Flammability and Explosibility

Non flammable

Safety Profile

Mildly toxic by ingestion. A human and experimental skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.

Synthesis

Dodecyl aldehyde is synthesized by catalytic dehydrogenation of Dodecanol (Lauryl alcohol).

Metabolism

See monograph on aldehyde C-8*

Purification Methods

Convert lauraldehyde to the bisufite addition compound by shaking with saturated aqueous NaHSO3 for 1hour. The precipitate is filtered off, washed with ice cold water, EtOH and ether, then decomposed with aqueous Na2CO3. The aldehyde is extracted into diethyl ether which, after drying and evaporating, gives an oil which is fractionally distilled under vacuum. [Beilstein 1 IV 3380.]