ChemicalBook > CAS DataBase List > METHYL 3,5-DIHYDROXYBENZOATE

METHYL 3,5-DIHYDROXYBENZOATE

Product Name: METHYL 3,5-DIHYDROXYBENZOATE
CAS No.: 2150-45-0
Chemical Name: METHYL 3,5-DIHYDROXYBENZOATE
Synonyms: AKOS 227-38;RARECHEM AL BF 0252;METHYL-A-RESORCYLATE;ALPHA-RESORCYLIC ACID MET;METHYL 2,6-DIHYDROXYBENZOATE;Methyl2,6-Dihydroxybenzoate>Dihydroxybenziocacidmethylester;Methyl 2,6-dihydroxybenzoate 97%;GAMMA-RESORCYLIC ACID METHYL ESTER;ALPHA-RESORCYLIC ACID METHYL ESTER
CBNumber: CB1192188
Molecular Formula: C8H8O4
Formula Weight: 168.15
MOL File: 2150-45-0.mol

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METHYL 3,5-DIHYDROXYBENZOATE Property

Melting point:: 67-70 °C (lit.)
Boiling point:: 253.6±20.0 °C(Predicted)
Density: 1.354±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Acetone (Slightly), Methanol (Slightly)
form: Solid
pka: 9.24±0.10(Predicted)
color: Light Brown
InChI: InChI=1S/C8H8O4/c1-12-8(11)7-5(9)3-2-4-6(7)10/h2-4,9-10H,1H3
InChIKey: WCQZCKUNZVMBDC-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=C(O)C=CC=C1O
LogP: 2.290 (est)
CAS DataBase Reference: 2150-45-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29182900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 432792
Product name: Methyl 2,6-dihydroxybenzoate
Purity: 97%
Packaging: 1g
Price: $34
Updated: 2023/01/07

TCI Chemical

Product number: D1461
Product name: Methyl 2,6-Dihydroxybenzoate
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $95
Updated: 2025/07/31

TCI Chemical

Product number: D1461
Product name: Methyl 2,6-Dihydroxybenzoate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $281
Updated: 2025/07/31

Usbiological

Product number: 009922
Product name: 3,5-Dihydroxybenzoic Acid Methyl Ester
Packaging: 5g
Price: $418
Updated: 2021/12/16

TRC

Product number: M305175
Product name: Methyl 2,6-dihydroxybenzoate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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METHYL 3,5-DIHYDROXYBENZOATE Chemical Properties,Usage,Production

Uses

Methyl 2,6-dihydroxybenzoate may be used for the preparation of methyl 2-hydroxy-6-methoxybenzoate and oxamyl propionic acid.

Definition

ChEBI: Methyl 2,6-dihydroxybenzoate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

General Description

Methyl 2,6-dihydroxybenzoate can be synthesized from 2,6-dihydroxybenzoic acid. Multiple fluorescences in methyl 2,6-dihydroxybenzoate have been investigated. Its short wavelength (387) and long wavelength (500) emissions are reported to arise from extramolecularly hydrogen-bonded and intramolecularly hydrogen-bonded species.

Synthesis

303-07-1

2150-45-0

The general procedure for the synthesis of methyl 2,6-dihydroxybenzoate from 2,6-dihydroxybenzoic acid is as follows: a) 80% sodium hydride (10.00 g, 333.3 mmol) was dissolved in N,N-dimethylformamide (45 mL) under argon protection and the solution was cooled to 0°C. Subsequently, a solution of 2,6-dihydroxybenzoic acid (48.88 g, 317.1 mmol) in N,N-dimethylformamide (50 mL) was slowly added over 45 minutes. After stirring for 45 minutes, iodomethane (21.0 mL, 337 mmol) was added dropwise over 20 minutes. The reaction mixture was stirred at room temperature for 70 hours. Upon completion of the reaction, the mixture was diluted with dichloromethane and filtered through a silica gel plug, using dichloromethane as the eluent. Finally, the solvent was evaporated to afford the target product methyl 2,6-dihydroxybenzoate (35.22 g, 66.1% yield). The product was characterized by 1H NMR (250 MHz, DMSO-d6): δ 9.91 (s, 2H), 7.09 (t, J = 1.2 Hz, J = 2.5 Hz, 1H), 6.37 (d, J = 1.1 Hz, 2H), 3.78 (s, 3H).

References

[1] Patent: US6204294, 2001, B1
[2] Patent: US4663344, 1987, A
[3] Patent: US6200981, 2001, B1

METHYL 3,5-DIHYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from METHYL 3,5-DIHYDROXYBENZOATE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Henan Fengda Chemical Co., Ltd

Product: METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
Price: US $101.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-29

Zhuozhou Wenxi import and Export Co., Ltd

Product: METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

2150-45-0, METHYL 3,5-DIHYDROXYBENZOATERelated Search:

Mofloverine METHYL 3,5-DIHYDROXYBENZOATE METHYL 2,4,6-TRIHYDROXYBENZOATE Methyl 2,6-dimethoxybenzoate CURCULIGOSIDE Methyl 2,5-dihydroxybenzoate Methyl 2,4-dihydroxybenzoate Methyl 3,4-dihydroxybenzoate Methyl 3,5-dihydroxybenzoate METHYL 2,3-DIHYDROXYBENZOATE 3,5-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid Methyl benzoate purpactin A 2,4,6-TRIMETHOXY-BENZOIC ACID METHYL ESTER METHYL 2,6-DIHYDROXY-4-METHYLBENZOATE Ethyl-1,3-dihydroxy-2-naphtoate METHYL 2,6-DIMETHOXY-3-NITROBENZOATE

GAMMA-RESORCYLIC ACID METHYL ESTER

2,6-DIHYDROXYBENZOIC ACID METHYL ESTER

3,5-DIHYDROXYBENZOIC ACID METHYL ESTER

AKOS 227-38

ALPHA-RESORCYLIC ACID METHYL ESTER

RARECHEM AL BF 0252

METHYL 2,6-DIHYDROXYBENZOATE

METHYL-A-RESORCYLATE

Benzoic acid, 2,6-dihydroxy-, methyl ester

2,6-DIHYDROXYBENZOIC ACID METHYL ESTER 99+%

Dihydroxybenziocacidmethylester

2,6-Dihydroxybenzoic Acid Methyl Ester gamma-Resorcylic Acid Methyl Ester

2-(Methoxycarbonyl)benzene-1,3-diol, 2-(Methoxycarbonyl)resorcinol

Methyl 2,6-dihydroxybenzoate 97%

ALPHA-RESORCYLIC ACID MET

Methyl2,6-Dihydroxybenzoate&gt

Benzoic acid, 2,6-dihydroxy-, methyl ester (9CI, ACI)

2,6-dihydroxy-Benzoic acid methyl ester (9CI ACI)

2150-45-0

HO2C6H3CO2CH3

Building Blocks for Dendrimers

Esters

Organic Building Blocks

Building Blocks

Carbonyl Compounds

C8 to C9

Aromatic Esters

Esters

Phenyls & Phenyl-Het

C8 to C9

Carbonyl Compounds