METHYL 3,5-DIHYDROXYBENZOATE
- Product Name
- METHYL 3,5-DIHYDROXYBENZOATE
- CAS No.
- 2150-45-0
- Chemical Name
- METHYL 3,5-DIHYDROXYBENZOATE
- Synonyms
- AKOS 227-38;RARECHEM AL BF 0252;METHYL-A-RESORCYLATE;ALPHA-RESORCYLIC ACID MET;METHYL 2,6-DIHYDROXYBENZOATE;Methyl2,6-Dihydroxybenzoate>Dihydroxybenziocacidmethylester;Methyl 2,6-dihydroxybenzoate 97%;GAMMA-RESORCYLIC ACID METHYL ESTER;ALPHA-RESORCYLIC ACID METHYL ESTER
- CBNumber
- CB1192188
- Molecular Formula
- C8H8O4
- Formula Weight
- 168.15
- MOL File
- 2150-45-0.mol
METHYL 3,5-DIHYDROXYBENZOATE Property
- Melting point:
- 67-70 °C (lit.)
- Boiling point:
- 253.6±20.0 °C(Predicted)
- Density
- 1.354±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Acetone (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.24±0.10(Predicted)
- color
- Light Brown
- InChI
- InChI=1S/C8H8O4/c1-12-8(11)7-5(9)3-2-4-6(7)10/h2-4,9-10H,1H3
- InChIKey
- WCQZCKUNZVMBDC-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=C(O)C=CC=C1O
- LogP
- 2.290 (est)
- CAS DataBase Reference
- 2150-45-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29182900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 432792
- Product name
- Methyl 2,6-dihydroxybenzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $34
- Updated
- 2023/01/07
- Product number
- D1461
- Product name
- Methyl 2,6-Dihydroxybenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- D1461
- Product name
- Methyl 2,6-Dihydroxybenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $281
- Updated
- 2025/07/31
- Product number
- M305175
- Product name
- Methyl 2,6-dihydroxybenzoate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M305175
- Product name
- Methyl 2,6-dihydroxybenzoate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
METHYL 3,5-DIHYDROXYBENZOATE Chemical Properties,Usage,Production
Uses
Methyl 2,6-dihydroxybenzoate may be used for the preparation of methyl 2-hydroxy-6-methoxybenzoate and oxamyl propionic acid.
Definition
ChEBI: Methyl 2,6-dihydroxybenzoate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.
General Description
Methyl 2,6-dihydroxybenzoate can be synthesized from 2,6-dihydroxybenzoic acid. Multiple fluorescences in methyl 2,6-dihydroxybenzoate have been investigated. Its short wavelength (387) and long wavelength (500) emissions are reported to arise from extramolecularly hydrogen-bonded and intramolecularly hydrogen-bonded species.
Synthesis
303-07-1
2150-45-0
The general procedure for the synthesis of methyl 2,6-dihydroxybenzoate from 2,6-dihydroxybenzoic acid is as follows: a) 80% sodium hydride (10.00 g, 333.3 mmol) was dissolved in N,N-dimethylformamide (45 mL) under argon protection and the solution was cooled to 0°C. Subsequently, a solution of 2,6-dihydroxybenzoic acid (48.88 g, 317.1 mmol) in N,N-dimethylformamide (50 mL) was slowly added over 45 minutes. After stirring for 45 minutes, iodomethane (21.0 mL, 337 mmol) was added dropwise over 20 minutes. The reaction mixture was stirred at room temperature for 70 hours. Upon completion of the reaction, the mixture was diluted with dichloromethane and filtered through a silica gel plug, using dichloromethane as the eluent. Finally, the solvent was evaporated to afford the target product methyl 2,6-dihydroxybenzoate (35.22 g, 66.1% yield). The product was characterized by 1H NMR (250 MHz, DMSO-d6): δ 9.91 (s, 2H), 7.09 (t, J = 1.2 Hz, J = 2.5 Hz, 1H), 6.37 (d, J = 1.1 Hz, 2H), 3.78 (s, 3H).
References
[1] Patent: US6204294, 2001, B1
[2] Patent: US4663344, 1987, A
[3] Patent: US6200981, 2001, B1
METHYL 3,5-DIHYDROXYBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 3,5-DIHYDROXYBENZOATE Suppliers
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View Lastest Price from METHYL 3,5-DIHYDROXYBENZOATE manufacturers
- Product
- METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10
- Product
- METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-29
- Product
- METHYL 3,5-DIHYDROXYBENZOATE 2150-45-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11