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2-IMINO-4-METHYLPIPERIDINE ACETATE

Product Name
2-IMINO-4-METHYLPIPERIDINE ACETATE
CAS No.
165383-72-2
Chemical Name
2-IMINO-4-METHYLPIPERIDINE ACETATE
Synonyms
NOS-IN-1;NOS-IN-1u00A0;QNJYWSIQJFUBOR-UHFFFAOYSA-N;NOS-IN-1u00A0, 10 mM in DMSO;2-IMINO-4-METHYLPIPERIDINE ACETATE;(2)-IMINO-4-METHYLPIPERIDINE ACETATE SALT;4-Methyl-3,4,5,6-tetrahydropyridin-2-aMine acetate;3,4,5,6-TETRAHYDRO-4-METHYL-2-PYRIDINAMINE, ACETATE;2-Pyridinamine, 3,4,5,6-tetrahydro-4-methyl-, acetate (1:1);Nitric oxide synthases,NOS IN 1?,oral,NOS,iNOS,NO Synthase,eNOS,nNOS,NOSIN1?,nitrate,Inhibitor,inhibit,nitrite
CBNumber
CB1193822
Molecular Formula
C8H16N2O2
Formula Weight
172.22
MOL File
165383-72-2.mol
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2-IMINO-4-METHYLPIPERIDINE ACETATE Property

Melting point:
181-182°C
storage temp. 
Store at -20°C
solubility 
DMF: >5 mg/ml; DMSO: >6.5 mg/ml; Ethanol: >23 mg/ml; PBS pH 7.2: >25 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
81015
Product name
2-Imino-4-methylpiperidine (acetate)
Purity
≥98%
Packaging
5mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
81015
Product name
2-Imino-4-methylpiperidine (acetate)
Purity
≥98%
Packaging
10mg
Price
$67
Updated
2024/03/01
Cayman Chemical
Product number
81015
Product name
2-Imino-4-methylpiperidine (acetate)
Purity
≥98%
Packaging
25mg
Price
$146
Updated
2024/03/01
Cayman Chemical
Product number
81015
Product name
2-Imino-4-methylpiperidine (acetate)
Purity
≥98%
Packaging
50mg
Price
$201
Updated
2024/03/01
AK Scientific
Product number
1356AH
Product name
2-Imino-4-methylpiperidineacetate
Packaging
25mg
Price
$262
Updated
2021/12/16
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2-IMINO-4-METHYLPIPERIDINE ACETATE Chemical Properties,Usage,Production

Description

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM.

Uses

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM.

Uses

A potent inhibitor of human iNOS (hNOS II).

in vivo

Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay[1].

References

[1] R. KEITH WEBBER. Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms?[J]. Journal of Medicinal Chemistry, 1998, 41 1: 96-101. DOI: 10.1021/jm9705059

2-IMINO-4-METHYLPIPERIDINE ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-IMINO-4-METHYLPIPERIDINE ACETATE Suppliers

Canada 1 China 36 France 1 Switzerland 2 United Kingdom 3 United States 9 USA 1 Global 53
MOLEKULA Ltd.
Tel
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Fax
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Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
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66
Fluorochem Ltd
Tel
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Fax
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Email
vernam@fluorochem.co.uk
Country
United Kingdom
ProdList
6375
Advantage
65
Fluorochem Ltd.
Tel
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Fax
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Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74

165383-72-2, 2-IMINO-4-METHYLPIPERIDINE ACETATERelated Search:

2-IMINO-4-METHYLPIPERIDINE ACETATE 3-METHYL-BUTYRAMIDINE 2-IMINO-4,6-DIMETHYLPIPERIDINE, ACETATE CHEMBRDG-BB 4012909 BUTYRAMIDINE

  • 4-Methyl-3,4,5,6-tetrahydropyridin-2-aMine acetate
  • QNJYWSIQJFUBOR-UHFFFAOYSA-N
  • 2-IMINO-4-METHYLPIPERIDINE ACETATE
  • (2)-IMINO-4-METHYLPIPERIDINE ACETATE SALT
  • 3,4,5,6-TETRAHYDRO-4-METHYL-2-PYRIDINAMINE, ACETATE
  • NOS-IN-1
  • Nitric oxide synthases,NOS IN 1?,oral,NOS,iNOS,NO Synthase,eNOS,nNOS,NOSIN1?,nitrate,Inhibitor,inhibit,nitrite
  • 2-Pyridinamine, 3,4,5,6-tetrahydro-4-methyl-, acetate (1:1)
  • NOS-IN-1u00A0
  • NOS-IN-1u00A0, 10 mM in DMSO
  • 165383-72-2
  • C6H12N2C2H4O2
  • C6H12N2C2H3O2
  • Nitric Oxide Reagents