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LEUPEPTIN TRIFLUOROACETATE SALT

Product Name
LEUPEPTIN TRIFLUOROACETATE SALT
CAS No.
147385-61-3
Chemical Name
LEUPEPTIN TRIFLUOROACETATE SALT
Synonyms
LEUPEPTIN TRIFLUOROACETATE SALT;leupeptintrifluoroacetatesalt90+%;ACETYL-LEU-LEU-ARG-AL TRIFLUOROACETATE SALT;LEUPEPTIN TRIFLUOROACETATE FROM*MICROBIA L SOURCE;Leupeptin trifluoroacetate salt >=90% (HPLC), microbial;Leupeptin trifluoroacetate salt,Acetyl-Leu-Leu-Arg-al trifluoroacetate salt;2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide,2,2,2-trifluoroaceticaci
CBNumber
CB1194874
Molecular Formula
C22H39F3N6O6
Formula Weight
540.58
MOL File
147385-61-3.mol
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LEUPEPTIN TRIFLUOROACETATE SALT Property

storage temp. 
-20°C
solubility 
H2O: 10 mM Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20°C.
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2925290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L2023
Product name
Leupeptin trifluoroacetate salt
Purity
≥90% (HPLC), microbial
Packaging
1mg
Price
$68.5
Updated
2024/03/01
Sigma-Aldrich
Product number
L2023
Product name
Leupeptin trifluoroacetate salt
Purity
≥90% (HPLC), microbial
Packaging
5mg
Price
$136
Updated
2024/03/01
Sigma-Aldrich
Product number
L2023
Product name
Leupeptin trifluoroacetate salt
Purity
≥90% (HPLC), microbial
Packaging
10mg
Price
$238
Updated
2024/03/01
Sigma-Aldrich
Product number
L2023
Product name
Leupeptin trifluoroacetate salt
Purity
≥90% (HPLC), microbial
Packaging
25mg
Price
$433
Updated
2024/03/01
Sigma-Aldrich
Product number
L2023
Product name
Leupeptin trifluoroacetate salt
Purity
≥90% (HPLC), microbial
Packaging
50mg
Price
$758
Updated
2024/03/01
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LEUPEPTIN TRIFLUOROACETATE SALT Chemical Properties,Usage,Production

Uses

Leupeptin Trifluoroacetate is a protease inhibitor, used in the characterization of macroautophagic flux in vivo using leupeptin-based assay.

Biochem/physiol Actions

Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)

LEUPEPTIN TRIFLUOROACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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LEUPEPTIN TRIFLUOROACETATE SALT Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

147385-61-3, LEUPEPTIN TRIFLUOROACETATE SALTRelated Search:


  • LEUPEPTIN TRIFLUOROACETATE SALT
  • ACETYL-LEU-LEU-ARG-AL TRIFLUOROACETATE SALT
  • LEUPEPTIN TRIFLUOROACETATE FROM*MICROBIA L SOURCE
  • leupeptintrifluoroacetatesalt90+%
  • Leupeptin trifluoroacetate salt,Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
  • Leupeptin trifluoroacetate salt >=90% (HPLC), microbial
  • 2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide,2,2,2-trifluoroaceticaci
  • 147385-61-3
  • C19H38N6O4C2HF3O2
  • C20H38N6O4C2HF3O2
  • Trypsin Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Analytical Enzymes
  • BioChemical
  • Biochemicals and Reagents
  • A to C
  • alpha
  • Apoptosis Enzymes
  • Application Index
  • Calpain II
  • Calpain II Inhibitors
  • Cathepsin B
  • Cathepsin H
  • Cathepsin/Granzyme Inhibitors &amp
  • Cell Signaling Enzymes
  • Coagulation Proteins and Reagents
  • D to K
  • Endoproteinase Lys-C
  • General Inhibitors
  • Kallikrein tissue
  • Aldehydes
  • and Substrates
  • Bioactive Small Molecules
  • Biochemicals and Reagents
  • Building Blocks
  • C13-C60
  • Calpain
  • Carbonyl Compounds
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Chemical Synthesis
  • Chymotrypsin
  • Core Bioreagents
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes
  • Inhibitors
  • L
  • Lys
  • Substrates
  • inhibitor