ChemicalBook > CAS DataBase List > 8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Product Name
- 8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- CAS No.
- 510774-50-2
- Chemical Name
- 8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms
- 8-CPT-2'-O-ME CAMP NA;CAMP, 8-CPT-2'-O-ME, NA;-O-methyladenosine3’8CPT-2ME-CAMP, SODIUM SALT;-cyclicMonophosphateSodiumSalt;8-(4-Chlorophenylthio)-2’8-PCPT-2''-O-ME-CAMP SODIUM SALT;8-[(4-Chlorophenyl)thio]-2'-O-methyladenosine cyclic 3',5'-(hydrogen phosphate);8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
- CBNumber
- CB1194975
- Molecular Formula
- C17H17ClN5O6PS
- Formula Weight
- 485.84
- MOL File
- Mol file
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8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Property
- Boiling point:
- 748.9±70.0 °C(Predicted)
- Density
- 1.95±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at -20°C
- form
- White to off-white crystalline powder.
- pka
- 0.92±0.60(Predicted)
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N-Bromosuccinimide Price
Tocris
- Product number
- 1645
- Product name
- 8-CPT-2Me-cAMP,sodiumsalt
- Purity
- ≥99%(HPLC)
- Packaging
- 1
- Price
- $195
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- NC10431
- Product name
- 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
- Packaging
- 2mg
- Price
- $250
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- NC10431
- Product name
- 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
- Packaging
- 5mg
- Price
- $525
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- NC10431
- Product name
- 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
- Packaging
- 10mg
- Price
- $945
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- NC10431
- Product name
- 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
- Packaging
- 25mg
- Price
- $1969
- Updated
- 2021/12/16
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8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties,Usage,Production
Uses
8-(4-Chlorophenylthio)-2''-O-methyladenosine 3'',5''-cyclic Monophosphate sodium salt is an activator of the Epac cAMP receptor. It can be used in biological study of interaction between TCL1 and Epac1 in activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages
Biological Activity
Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC 50 = 2.2 mM), but not PKA (EC 50 > 10 mM). Stimulates Epac-mediated Ca 2+ -mediated Ca 2+ release in pancreatic b-cells in vitro .
8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Suppliers
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