3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE

Product Name: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE
CAS No.: 106058-85-9
Chemical Name: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE
Synonyms: 3-ACETYL-N-TOSYLPYRROLE;3-ACETYL-1-TOSYLPYRROLE;1-TOSYL-3-ACETYLPYRROLE;1-(1-Tosyl-1H-pyrrol-3-yl)ethanone;3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE;1-(4-Tolylsulfonyl)-3-acetylpyrrole;3-acetyl-N-p-toluenesulfonylpyrrole;1-(1-tosyl-1h-pyrrol-3-yl)ethan-1-one;1-[1-(4-methylphenyl)sulfonyl-3-pyrrolyl]ethanone;1-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-3-yl}ethanone
CBNumber: CB1195154
Molecular Formula: C13H13NO3S
Formula Weight: 263.31
MOL File: 106058-85-9.mol

More

Less

3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Property

Melting point:: 68-72°C
Boiling point:: 88 °C
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -11.38±0.70(Predicted)
Appearance: White to off-white Solid

More

Less

Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: T686958
Product name: 1-(1-Tosyl-1H-pyrrol-3-yl)ethanone
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: OR10308
Product name: 3-Acetyl-1-tosylpyrrole
Packaging: 25g
Price: $148
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H69-1-52
Product name: 3-Acetyl-1-tosylpyrrole
Purity: 97%
Packaging: 25g
Price: $175
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0023030
Product name: 3-ACETYL-1-(PARA-TOLYLSULFONYL)PYRROLE
Purity: 95.00%
Packaging: 1G
Price: $721.57
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0023030
Product name: 3-ACETYL-1-(PARA-TOLYLSULFONYL)PYRROLE
Purity: 95.00%
Packaging: 2.5G
Price: $983.88
Updated: 2021/12/16

More

Less

3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Chemical Properties,Usage,Production

Synthesis

17639-64-4

108-24-7

106058-85-9

GENERAL STEPS: Acetic anhydride (0.44 mL, 4.7 mmol) was slowly added dropwise to a solution of dichloromethane (5.22 mL) containing aluminum chloride (896 mg, 6.7 mmol) at room temperature. After stirring the reaction mixture for 10 minutes, a solution of N-tosylpyrrole (400 mg, 1.81 mmol) in dichloromethane (0.9 mL) was added dropwise. Stirring of the reaction mixture was continued for 2 hours. Upon completion of the reaction, the mixture was poured into an ice-water mixture. The organic phase was separated and the aqueous phase was extracted with dichloromethane. The organic phases were combined, washed with 1N NaOH aqueous solution and dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated to obtain the crude product. The crude product was washed with methanol and further purified to give 1-(1-toluenesulfonyl-1H-pyrrol-3-yl)ethanone (470 mg, 1.78 mmol, 99% yield) as a pure solid. Thin layer chromatography (TLC) analysis showed an Rf value of 0.5 (unfolding agent: hexane/ethyl acetate, 6/4). The structure of the product was confirmed by 1H NMR spectroscopy [24].

References

[1] Journal of Heterocyclic Chemistry, 2009, vol. 46, # 6, p. 1285 - 1295
[2] European Journal of Medicinal Chemistry, 2012, vol. 57, p. 391 - 397
[3] Patent: US2006/189555, 2006, A1. Location in patent: Page/Page column 10
[4] European Journal of Organic Chemistry, 2018, vol. 2018, # 1, p. 60 - 77
[5] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7899 - 7902

3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Suppliers

China 42 Germany 3 India 1 Japan 1 United Kingdom 4 United States 7 Global 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 891
Advantage: 68

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3199
Advantage: 55

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

106058-85-9, 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLERelated Search:

1-Tosylpyrrole 3-ACETYLPYRROLE 2-ACETYL-1-TOSYLPYRROLE 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE (2,2-DICHLOROCYCLOPROPYL)(1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROL-3-YL)METHANONE 3-ACETYL-2,4-DIMETHYL-1-TOSYLPYRROLE 3-(CHLOROACETYL)-1-TOSYLPYRROLE PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE 1-[(4-METHYLPHENYL)SULFONYL]-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONE 3-(BROMOACETYL)-2,4-DIMETHYL-1-TOSYLPYRROLE

1-TOSYL-3-ACETYLPYRROLE

1-(1-Tosyl-1H-pyrrol-3-yl)ethanone

1-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-3-yl}ethanone

1-(4-Tolylsulfonyl)-3-acetylpyrrole

3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE

3-ACETYL-1-TOSYLPYRROLE

3-ACETYL-N-TOSYLPYRROLE

3-acetyl-N-p-toluenesulfonylpyrrole

1-[1-(4-methylphenyl)sulfonyl-3-pyrrolyl]ethanone

Ethanone, 1-[1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-3-yl]-

1-(1-tosyl-1h-pyrrol-3-yl)ethan-1-one

106058-85-9

Azoles

blocks