LATHOSTEROL

Product Name: LATHOSTEROL
CAS No.: 80-99-9
Chemical Name: LATHOSTEROL
Synonyms: LATHOSTEROL;-Cholestenol;γ-Cholestenol;GAMMA-CHOLESTENOL;Cholest-7-en-3-ol;gamma-cholesterol;DELTA7-Cholestenol;7-En-3-cholestanol;5Α-CHOLEST-7-EN-3-OL;7-Cholesten-3-beta-ol
CBNumber: CB1197244
Molecular Formula: C27H46O
Formula Weight: 386.65
MOL File: 80-99-9.mol

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LATHOSTEROL Property

Melting point:: 126°C
Boiling point:: 452.8°C (rough estimate)
Density: 0.9610 (rough estimate)
refractive index: 1.5250 (estimate)
storage temp.: -20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 15.10±0.70(Predicted)
color: White to Off-White

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Safety

WGK Germany: 3
RTECS: FZ7000000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C3652
Product name: 5α-Cholest-7-en-3β-ol
Packaging: 25mg
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: C3652
Product name: 5α-Cholest-7-en-3β-ol
Packaging: 100mg
Price: $352
Updated: 2024/03/01

Cayman Chemical

Product number: 9003102
Product name: Lathosterol
Purity: ≥98%
Packaging: 10mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 9003102
Product name: Lathosterol
Purity: ≥98%
Packaging: 25mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 9003102
Product name: Lathosterol
Purity: ≥98%
Packaging: 50mg
Price: $139
Updated: 2024/03/01

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LATHOSTEROL Chemical Properties,Usage,Production

Uses

A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.

Uses

Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.

Uses

5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.

Definition

ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.

General Description

Lathosterol is a cholesterol synthesis precursor.

Biochem/physiol Actions

5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.

IC 50

Human Endogenous Metabolite

LATHOSTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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LATHOSTEROL Suppliers

Canada 1 China 78 India 3 Switzerland 1 United Kingdom 1 United States 10 Global 94

J & K SCIENTIFIC LTD.

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Sigma-Aldrich

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80-99-9, LATHOSTEROLRelated Search:

Lathosterol-1,2,5alpha,6alpha-D4 lathosterol delta-5-dehydrogenase Lathosterol TMS (Lathosterol-1,2,5α,6α-D4) 7,5ALPHA-CHOLESTEN-4ALPHA-METHYL-3BETA-OL 5ALPHA-CHOLEST-7-EN-3BETA-OL-1,2,5,6-D4 7,5ALPHA-CHOLESTEN-4ALPHA-METHYL-3BETA-OL 3-ACETATE 5-alpha-ergost-7-en-3-beta-ol AGOSTEROL A LATHOSTEROL

3BETA-HYDROXY-5ALPHA,7-CHOLESTENE

5ALPHA-CHOLEST-7-EN-3BETA-OL

7,(5-ALPHA)-CHOLESTEN-3-BETA-OL

LATHOSTEROL

GAMMA-CHOLESTENOL

(3-beta,5-alpha)-cholest-7-en-3-o

3beta-Hydroxy-5alpha-cholest-7-ene

7-Cholesten-3-beta-ol

Cholest-7-en-3-ol

Cholest-7-en-3-ol, (3beta,5alpha)-

delta(Sup7)-Cholestenol

DELTA7-Cholestenol

gamma-cholesterol

5A-cholest-7-en-3B-ol

3β-hydroxy-5α,7-cholestene

5α-cholest-7-en-3β-ol

10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

3β-Hydroxy-5α,7-cholestene, Lathosterol

(3β,5α)-Cholest-7-en-3-ol

3β-Hydroxy-5α-cholest-7-ene

7-En-3-cholestanol

γ-Cholestenol

5Α-CHOLEST-7-EN-3-OL;LATHOSTEROL

Cholest-7-en-3-ol, (3β,5α)-

(3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

Cholest-7-en-3-ol, (3b,5a)-

5α-c h ole st-7-e n-3β-ol (la th oste rol)

Inhibitor,Endogenous Metabolite,Lathosterol,inhibit

Cholesterol Impurity 16 (Lathosterol)

(3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol,

7, (5α)-CHOLESTEN-3β-OL

5Α-CHOLEST-7-EN-3-OL

-Cholestenol

80-99-9

Biochemicals and Reagents

BioChemical

Cholesterol and Derivatives

Lipids

Sterols

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids