ChemicalBook > CAS DataBase List > LATHOSTEROL

LATHOSTEROL

Product Name
LATHOSTEROL
CAS No.
80-99-9
Chemical Name
LATHOSTEROL
Synonyms
LATHOSTEROL;-Cholestenol;γ-Cholestenol;GAMMA-CHOLESTENOL;Cholest-7-en-3-ol;gamma-cholesterol;DELTA7-Cholestenol;7-En-3-cholestanol;5Α-CHOLEST-7-EN-3-OL;7-Cholesten-3-beta-ol
CBNumber
CB1197244
Molecular Formula
C27H46O
Formula Weight
386.65
MOL File
80-99-9.mol
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LATHOSTEROL Property

Melting point:
126°C
Boiling point:
452.8°C (rough estimate)
Density 
0.9610 (rough estimate)
refractive index 
1.5250 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
15.10±0.70(Predicted)
color 
White to Off-White
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Safety

WGK Germany 
3
RTECS 
FZ7000000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C3652
Product name
5α-Cholest-7-en-3β-ol
Packaging
25mg
Price
$114
Updated
2025/07/31
Sigma-Aldrich
Product number
C3652
Product name
5α-Cholest-7-en-3β-ol
Packaging
100mg
Price
$362
Updated
2025/07/31
Cayman Chemical
Product number
9003102
Product name
Lathosterol
Purity
≥98%
Packaging
10mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
9003102
Product name
Lathosterol
Purity
≥98%
Packaging
25mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
9003102
Product name
Lathosterol
Purity
≥98%
Packaging
50mg
Price
$139
Updated
2024/03/01
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LATHOSTEROL Chemical Properties,Usage,Production

Uses

A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.

Uses

Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.

Uses

5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.

Definition

ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.

General Description

Lathosterol is a cholesterol synthesis precursor.

Biochem/physiol Actions

5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.

IC 50

Human Endogenous Metabolite

LATHOSTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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80-99-9, LATHOSTEROLRelated Search:


  • 3BETA-HYDROXY-5ALPHA,7-CHOLESTENE
  • 5ALPHA-CHOLEST-7-EN-3BETA-OL
  • 7,(5-ALPHA)-CHOLESTEN-3-BETA-OL
  • LATHOSTEROL
  • GAMMA-CHOLESTENOL
  • (3-beta,5-alpha)-cholest-7-en-3-o
  • 3beta-Hydroxy-5alpha-cholest-7-ene
  • 7-Cholesten-3-beta-ol
  • Cholest-7-en-3-ol
  • Cholest-7-en-3-ol, (3beta,5alpha)-
  • delta(Sup7)-Cholestenol
  • DELTA7-Cholestenol
  • gamma-cholesterol
  • 5A-cholest-7-en-3B-ol
  • 3β-hydroxy-5α,7-cholestene
  • 5α-cholest-7-en-3β-ol
  • 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 3β-Hydroxy-5α,7-cholestene, Lathosterol
  • (3β,5α)-Cholest-7-en-3-ol
  • 3β-Hydroxy-5α-cholest-7-ene
  • 7-En-3-cholestanol
  • γ-Cholestenol
  • 5Α-CHOLEST-7-EN-3-OL;LATHOSTEROL
  • Cholest-7-en-3-ol, (3β,5α)-
  • (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • Cholest-7-en-3-ol, (3b,5a)-
  • 5α-c h ole st-7-e n-3β-ol (la th oste rol)
  • Inhibitor,Endogenous Metabolite,Lathosterol,inhibit
  • Cholesterol Impurity 16 (Lathosterol)
  • (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol,
  • 7, (5α)-CHOLESTEN-3β-OL
  • 5Α-CHOLEST-7-EN-3-OL
  • -Cholestenol
  • 80-99-9
  • Biochemicals and Reagents
  • BioChemical
  • Cholesterol and Derivatives
  • Lipids
  • Sterols
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids