4-BROMO-2-FLUOROBENZYL CYANIDE
- Product Name
- 4-BROMO-2-FLUOROBENZYL CYANIDE
- CAS No.
- 114897-91-5
- Chemical Name
- 4-BROMO-2-FLUOROBENZYL CYANIDE
- Synonyms
- 4-BROMO-2-FLUOROBENZYL CYANIDE;Fluoro-4-bromophenyl acetonitrile;4-bromo-2-fluorophenylacetonitrile;4-bromo-2-fluorobenzeneacetonitrile;2-Fluoro-4-bromobenzeneacetonitrile;4-Bromo-2-fluorobenzyl cyanide, 98+%;Benzeneacetonitrile, 4-bromo-2-fluoro-;2-(4-broMo-2-fluorophenyl)acetonitrile;4-BroMo-2-fluorobenzyl cyanide, 98+% 5GR;4-BroMo-2-fluorobenzyl cyanide, 98+% 25GR
- CBNumber
- CB1198786
- Molecular Formula
- C8H5BrFN
- Formula Weight
- 214.03
- MOL File
- 114897-91-5.mol
4-BROMO-2-FLUOROBENZYL CYANIDE Property
- Melting point:
- 52.8-53 °C
- Boiling point:
- 281℃
- Density
- 1.573
- Flash point:
- 124℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Crystalline Powder
- color
- White to beige
- CAS DataBase Reference
- 114897-91-5
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 36/37/39-26
- RIDADR
- 3439
- HazardClass
- 6.1
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- B692178
- Product name
- 4-Bromo-2-fluorobenzylcyanide
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC8933
- Product name
- 4-Bromo-2-fluorophenylacetonitrile
- Packaging
- 5g
- Price
- $13
- Updated
- 2021/12/16
- Product number
- 3737-B-42
- Product name
- 2-(4-Bromo-2-fluorophenyl)acetonitrile
- Purity
- 98%
- Packaging
- 5G
- Price
- $21
- Updated
- 2021/12/16
- Product number
- PC8933
- Product name
- 4-Bromo-2-fluorophenylacetonitrile
- Packaging
- 25g
- Price
- $28
- Updated
- 2021/12/16
- Product number
- 073884
- Product name
- 4-Bromo-2-fluorobenzyl cyanide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $40
- Updated
- 2021/12/16
4-BROMO-2-FLUOROBENZYL CYANIDE Chemical Properties,Usage,Production
Chemical Properties
White to beige crystalline powder
Synthesis
773837-37-9
76283-09-5
114897-91-5
The reaction was carried out with 4-bromo-2-fluorobenzyl bromide (26.8 g, 100 mmol) and sodium cyanide (5.4 g, 110 mmol) in a solvent mixture of ethanol (40 ml) and water (10 ml) with stirring at 100 °C for 8.5 hours. After completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure. The reaction mixture was extracted with ethyl acetate and the organic layer was washed with saturated sodium chloride solution and dried with anhydrous sodium sulfate. After drying, the desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 4-bromo-2-fluoro-benzyl cyanide (22.6 g, quantitative yield) as a black oil. The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3): δ 3.73 (2H, s), 7.27-7.38 (3H, m).
References
[1] Patent: EP2700643, 2014, A1. Location in patent: Paragraph 0188
[2] Patent: WO2004/74270, 2004, A2. Location in patent: Page 111-112
[3] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 54; 44; 56; 57
[4] Patent: WO2016/38519, 2016, A1. Location in patent: Page/Page column 36
[5] Patent: WO2016/38552, 2016, A1. Location in patent: Page/Page column 50
4-BROMO-2-FLUOROBENZYL CYANIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-BROMO-2-FLUOROBENZYL CYANIDE Suppliers
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
View Lastest Price from 4-BROMO-2-FLUOROBENZYL CYANIDE manufacturers
- Product
- 4-BROMO-2-FLUOROBENZYL CYANIDE 114897-91-5
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08