ChemicalBook > CAS DataBase List > 4-BROMO-2-FLUOROBENZYL CYANIDE

4-BROMO-2-FLUOROBENZYL CYANIDE

Product Name
4-BROMO-2-FLUOROBENZYL CYANIDE
CAS No.
114897-91-5
Chemical Name
4-BROMO-2-FLUOROBENZYL CYANIDE
Synonyms
4-BROMO-2-FLUOROBENZYL CYANIDE;Fluoro-4-bromophenyl acetonitrile;4-bromo-2-fluorophenylacetonitrile;4-bromo-2-fluorobenzeneacetonitrile;2-Fluoro-4-bromobenzeneacetonitrile;4-Bromo-2-fluorobenzyl cyanide, 98+%;Benzeneacetonitrile, 4-bromo-2-fluoro-;2-(4-broMo-2-fluorophenyl)acetonitrile;4-BroMo-2-fluorobenzyl cyanide, 98+% 5GR;4-BroMo-2-fluorobenzyl cyanide, 98+% 25GR
CBNumber
CB1198786
Molecular Formula
C8H5BrFN
Formula Weight
214.03
MOL File
114897-91-5.mol
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4-BROMO-2-FLUOROBENZYL CYANIDE Property

Melting point:
52.8-53 °C
Boiling point:
281℃
Density 
1.573
Flash point:
124℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
color 
White to beige
CAS DataBase Reference
114897-91-5
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26
RIDADR 
3439
HazardClass 
6.1
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
B692178
Product name
4-Bromo-2-fluorobenzylcyanide
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
073884
Product name
4-Bromo-2-fluorobenzyl cyanide
Purity
95+%
Packaging
10g
Price
$60
Updated
2021/12/16
AK Scientific
Product number
A886
Product name
2-Fluoro-4-bromobenzeneacetonitrile
Packaging
1g
Price
$64
Updated
2021/12/16
SynQuest Laboratories
Product number
3737-B-42
Product name
2-(4-Bromo-2-fluorophenyl)acetonitrile
Purity
98%
Packaging
25g
Price
$72
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK226767
Product name
4-Bromo-2-fluorobenzylcyanide
Purity
98%
Packaging
5g
Price
$80
Updated
2021/12/16
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4-BROMO-2-FLUOROBENZYL CYANIDE Chemical Properties,Usage,Production

Chemical Properties

White to beige crystalline powder

Synthesis

773837-37-9

76283-09-5

114897-91-5

The reaction was carried out with 4-bromo-2-fluorobenzyl bromide (26.8 g, 100 mmol) and sodium cyanide (5.4 g, 110 mmol) in a solvent mixture of ethanol (40 ml) and water (10 ml) with stirring at 100 °C for 8.5 hours. After completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure. The reaction mixture was extracted with ethyl acetate and the organic layer was washed with saturated sodium chloride solution and dried with anhydrous sodium sulfate. After drying, the desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 4-bromo-2-fluoro-benzyl cyanide (22.6 g, quantitative yield) as a black oil. The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3): δ 3.73 (2H, s), 7.27-7.38 (3H, m).

References

[1] Patent: EP2700643, 2014, A1. Location in patent: Paragraph 0188
[2] Patent: WO2004/74270, 2004, A2. Location in patent: Page 111-112
[3] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 54; 44; 56; 57
[4] Patent: WO2016/38519, 2016, A1. Location in patent: Page/Page column 36
[5] Patent: WO2016/38552, 2016, A1. Location in patent: Page/Page column 50

4-BROMO-2-FLUOROBENZYL CYANIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-2-FLUOROBENZYL CYANIDE Suppliers

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View Lastest Price from 4-BROMO-2-FLUOROBENZYL CYANIDE manufacturers

Career Henan Chemical Co
Product
4-BROMO-2-FLUOROBENZYL CYANIDE 114897-91-5
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

114897-91-5, 4-BROMO-2-FLUOROBENZYL CYANIDERelated Search:


  • 4-BroMo-2-fluorobenzyl cyanide, 98+% 5GR
  • Fluoro-4-bromophenyl acetonitrile
  • 4-bromo-2-fluorobenzeneacetonitrile
  • 4-BROMO-2-FLUOROBENZYL CYANIDE
  • 4-BroMo-2-fluorobenzyl cyanide, 98+% 25GR
  • 4-Bromo-2-fluorobenzyl cyanide, 98+%
  • 2-Fluoro-4-bromobenzeneacetonitrile
  • 4-bromo-2-fluorophenylacetonitrile
  • 2-(4-broMo-2-fluorophenyl)acetonitrile
  • Benzeneacetonitrile, 4-bromo-2-fluoro-
  • 114897-91-5