ChemicalBook > CAS DataBase List > 1-Methylindole-3-carboxaldehyde
1-Methylindole-3-carboxaldehyde
- Product Name
- 1-Methylindole-3-carboxaldehyde
- CAS No.
- 19012-03-4
- Chemical Name
- 1-Methylindole-3-carboxaldehyde
- Synonyms
- 1-METHYL-1H-INDOLE-3-CARBALDEHYDE;3-formyl-1-methylindole;NSC 83042;AKOS JY2082515;RARECHEM AH BS 0121;TIMTEC-BB SBB010057;N-Methyl-3-formylindole;ASINEX-REAG BAS 12967420;N-methyl-3-carboxaldehyde;1 METHYLINDOLE-3-ALDEHYDE
- CBNumber
- CB1201057
- Molecular Formula
- C10H9NO
- Formula Weight
- 159.18
- MOL File
- 19012-03-4.mol
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1-Methylindole-3-carboxaldehyde Property
- Melting point:
- 70-72 °C (lit.)
- Boiling point:
- 186-189 °C(Press: 3-4 Torr)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Crystalline Powder and Chunks
- color
- Light yellow to orange or brown
- Water Solubility
- Insoluble in water.
- Sensitive
- Air Sensitive
- BRN
- 121302
- CAS DataBase Reference
- 19012-03-4(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 357987
- Product name
- 1-Methylindole-3-carboxaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $85.2
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 357987
- Product name
- 1-Methylindole-3-carboxaldehyde
- Purity
- 97%
- Packaging
- 25g
- Price
- $515
- Updated
- 2023/06/20
Alfa Aesar
- Product number
- L02212
- Product name
- 1-Methylindole-3-carboxaldehyde, 98+%
- Packaging
- 1g
- Price
- $31.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L02212
- Product name
- 1-Methylindole-3-carboxaldehyde, 98+%
- Packaging
- 5g
- Price
- $80.65
- Updated
- 2024/03/01
SynQuest Laboratories
- Product number
- 4H15-1-0J
- Product name
- 1-Methyl-1H-indole-3-carboxaldehyde
- Purity
- 98%
- Packaging
- 5G
- Price
- $80
- Updated
- 2021/12/16
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1-Methylindole-3-carboxaldehyde Chemical Properties,Usage,Production
Chemical Properties
light yellow to orange or brown crystalline powder
Uses
Reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions Reactant for synthesis of quinolinones via three-component Ugi reaction Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture Reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins Reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent Reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents.
Uses
1-Methylindole-3-carboxaldehyde is used as a reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions, reactant for synthesis of quinolinones via three-component Ugi reaction, reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture, reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins, reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent, reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents 1-Methylindole-3-carboxaldehyde may be used in the synthesis of (Z)-3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile, via base-catalyzed condensation with thiophene-3-acetonitrile. It was also used in the preparation of monomer, required for the synthesis of poly(3-vinyl-1-methylindole).
Synthesis Reference(s)
Tetrahedron, 49, p. 4015, 1993 DOI: 10.1016/S0040-4020(01)89915-4
Synthesis, p. 396, 1987 DOI: 10.1055/s-1987-27960
General Description
1-Methylindole-3-carboxaldehyde is a heterocyclic indole aldehyde. 1-Methylindole-3-carboxaldehyde on condensation with 2-hydroxybenzohydrazide yields Schiff base.
1-Methylindole-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Methylindole-3-carboxaldehyde manufacturers
Hebei Mojin Biotechnology Co., Ltd
- Product
- 1-Methylindole-3-carboxaldehyde 19012-03-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2024-01-29
Shaanxi Dideu Medichem Co. Ltd
- Product
- 1-Methylindole-3-carboxaldehyde 19012-03-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-01-02
Henan Xiangtong Chemical Co., Ltd.
- Product
- 1-Methylindole-3-carboxaldehyde 19012-03-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100T
- Release date
- 2019-08-02
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