ChemicalBook > CAS DataBase List > Glycyrrhetinic acid sodium salt
Glycyrrhetinic acid sodium salt
- Product Name
- Glycyrrhetinic acid sodium salt
- CAS No.
- 1148013-87-9
- Chemical Name
- Glycyrrhetinic acid sodium salt
- Synonyms
- HENA;HENA >=98% (HPLC);Glycyrrhetinic acid sodium salt;(3b,20b)-3-Hydroxy-olean-12-en-29-oic acid sodium salt
- CBNumber
- CB12081598
- Molecular Formula
- C30H45NaO4
- Formula Weight
- 493
- MOL File
- 1148013-87-9.mol
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Glycyrrhetinic acid sodium salt Property
- storage temp.
- room temp
- solubility
- DMSO: soluble3mg/mL, clear (warmed)
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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Glycyrrhetinic acid sodium salt Chemical Properties,Usage,Production
Uses
11-Deoxyglycyrrhetinic acid sodium is a compound that exhibits anti-inflammatory activity. 11-Deoxyglycyrrhetinic acid sodium activates the Ca2+/voltage-gated K+ large conductance (BK) (cbv1 + β1) channels cloned from rat cerebral artery myocytes with the EC50 of 53 μM[1][2].
References
[1] Siviy SM, et al. Noradrenergic modulation of play in Sprague-Dawley and F344 rats. Psychopharmacology (Berl). 2023 Jul 10. DOI:10.1007/s00213-023-06419-2
[2] Bukiya AN, et al. Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent. Mol Pharmacol. 2013;83(5):1030-1044. DOI:10.1124/mol.112.083519
Glycyrrhetinic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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