Chemical Properties Uses
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18alpha-Glycyrrhetinic acid

Chemical Properties Uses
Product Name
18alpha-Glycyrrhetinic acid
CAS No.
1449-05-4
Chemical Name
18alpha-Glycyrrhetinic acid
Synonyms
Nsc 35350;Triterpene;Ccris 3963;Brn 2956366;Einecs 215-907-9;18α-Glycyrrhetinic;18a-Glycyrrhetic acid;18α-Glycyrrhetic acid;18A-GLYCYRRHETINIC ACID;beta-glycyrrhetinicacid
CBNumber
CB7172205
Molecular Formula
C30H46O4
Formula Weight
470.68
MOL File
1449-05-4.mol
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18alpha-Glycyrrhetinic acid Property

Melting point:
331-333°C
Boiling point:
492.11°C (rough estimate)
Density 
0.9967 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.71±0.70(Predicted)
color 
White to Off-White
LogP
6.570 (est)
CAS DataBase Reference
1449-05-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
ection
WGK Germany 
3
RTECS 
RK0190000
HS Code 
29189900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G8503
Product name
18α-Glycyrrhetinic acid
Purity
≥95%
Packaging
250mg
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
G8503
Product name
18α-Glycyrrhetinic acid
Purity
≥95%
Packaging
1g
Price
$254.4
Updated
2024/03/01
Usbiological
Product number
412321
Product name
18α-Glycyrrhetinic Acid
Packaging
100mg
Price
$460
Updated
2021/12/16
TRC
Product number
G735005
Product name
18α-Glycyrrhetinic acid
Packaging
500mg
Price
$660
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0017607
Product name
18ALPHA-GLYCYRRHETINIC ACID
Purity
95.00%
Packaging
1G
Price
$973.84
Updated
2021/12/16
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18alpha-Glycyrrhetinic acid Chemical Properties,Usage,Production

Chemical Properties

Glycyrrhetinic acid is a kind of glycoside composed of glycyrrhizic acid-ff two molecules glucuronic acid. It appears as white crystalline powder with sweet taste. The sweetness is about 200 times of the sucrose. Its sweetness is different from other sweeteners such as sucrose. After eating, you can sense the sweetness only after a few moments but the retention time is long. Combination of a small amount of glycyrrhizin and sucrose can save 20% sucrose without affecting the sweetness. Although having no aroma, it has incense effect. It has a melting point (decomposition) of 220 ° C. The aqueous solution is weakly acidic and can be treated by acid.

Uses

Sweeteners; sweetness improving agents; flavor enhancers (dairy products, cocoa products, egg products, mutton), flavoring agents (function well especially when used in combination with salt), Chinese folk mostly use it in sauce and sauce products, pickled goods and so on.

Uses

18α-Glycyrrhetinic acid may be used to synthesize:

  • 3-keto-18α-glycyrrhetinic acid
  • methyl esters of 18α-glycyrrhetinic acid
  • methyl esters of 3-keto-18α-glycyrrhetinic acid

General Description

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).

18alpha-Glycyrrhetinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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18alpha-Glycyrrhetinic acid Suppliers

Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
3999
Advantage
55
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-400-186-5138 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1007
Advantage
58
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Country
China
ProdList
281
Advantage
59
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View Lastest Price from 18alpha-Glycyrrhetinic acid manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Glycyrrhetinic acid 1449-05-4 1449-05-4
Price
US $7.50/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
18alpha-Glycyrrhetinic acid 1449-05-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
18alpha-Glycyrrhetinic acid 1449-05-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

1449-05-4, 18alpha-Glycyrrhetinic acidRelated Search:


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