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PIPERITONE

Product Name
PIPERITONE
CAS No.
89-81-6
Chemical Name
PIPERITONE
Synonyms
2-Cyclohexen-1-one, 3-methyl-6-(1-methylethyl)-;PIPERITON;3-methyl-6-(1-methylethyl)-2-Cyclohexen-1-one;PIPERTONE;ALPHA-PIPERITONE;P-MENTH-1-EN-3-ONE;94.0%(GC);PIPERITONE;Piperitone P;PIPERITONE(SG)
CBNumber
CB6273037
Molecular Formula
C10H16O
Formula Weight
152.23
MOL File
89-81-6.mol
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PIPERITONE Property

Melting point:
-29 °C
Boiling point:
233°C
Density 
0,93 g/cm3
FEMA 
2910 | D-PIPERITONE
refractive index 
-60 ° (C=4, benzene)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Oil
color 
Colourless to Pale Yellow
Odor
at 10.00 % in dipropylene glycol. herbal minty camphor medicinal
Odor Type
herbal
JECFA Number
435
Merck 
7473
LogP
2.4
EPA Substance Registry System
Piperitone (89-81-6)
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Safety

Safety Statements 
23-24/25
RTECS 
OT0257000
HS Code 
2914.29.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL82627
Product name
Piperitone
Purity
phyproof? Reference Substance
Packaging
100mg
Price
$268
Updated
2025/07/31
Sigma-Aldrich
Product number
79899
Product name
Piperitone
Purity
analytical standard
Packaging
10mg
Price
$85.3
Updated
2025/07/31
TCI Chemical
Product number
P1783
Product name
Piperitone (mixture of enantiomers, predominantly (R)-(-)-form)
Purity
>94.0%(GC)
Packaging
25g
Price
$58
Updated
2025/07/31
TCI Chemical
Product number
P2355
Product name
Piperitone (mixture of enantiomers)
Purity
min. 95.0 %
Packaging
25G
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
P2355
Product name
Piperitone (mixture of enantiomers)
Purity
min. 95.0 %
Packaging
100G
Price
$153
Updated
2024/03/01
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PIPERITONE Chemical Properties,Usage,Production

Chemical Properties

Monocyclic monoterpenes. There is a pair of enantiomers, both of which are naturally occurring. The right enantiomer has a camphoraceous odor, oily liquid, boiling point 232-235°C, relative density 0.9344, refractive index 1.4848, spin [α]20D +49.13°. Left spin body boiling point 109.5-110.5 ℃ (1.99kPa), relative density 0.9324, refractive index 1.4832, often in two optical isomers are present in a variety of essential oils.

Uses

Piperitone is a monoterpene compound that has a fresh minty camphor-like odour, and naturally occurs in extracts of commercial oil of peppermint. Piperitone is also used as a starting material in the synthesis of Thymol (T413000), a phenolic compound that is used for its antibacterial properties. The cyclic ketone is more commonly used in flavour compositions, particularly in spice complexes with Caraway, Estragon, etc., and in fruit complexes with mint flavours, etc. Now and then, it has become “fashionable” in dentifrice preparations where larger amounts are used. The concentration normally used is equivalent to about 1 to 20 ppm in the finished product.

Production Methods

Piperitone is produced:
by isolation from Japanese Mint oil (dextro-Piperitone),
by isolation from Eucalyptus dives oil (laevo-Piperitone),
by hydrogenation of Diosphenol,
by reduction of 5-Methyl-2-iso-propylanisole with Sodium in liquid Ammonia.
laevo-Piperitone can also be produced from laevo-beta-Pinene via l-Limonene, by hydrogenation to /-Carvomenthene, and via 4 further intermediate steps to Piperitone.

Definition

ChEBI: A p-menthane monoterpenoid that is cyclohex-2-en-1-one substituted by a methyl group at position 3 and an isopropyl group at position 6.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

in vivo

The insecticidal activity of crude essential oil extracted from Cymbopogon schoenanthus and of its main constituent, Piperitone, is assessed on different developmental stages of Callosobruchus maculatus (C. maculatus). Piperitone is toxic to C. maculatus adults with a LC50 value of 1.6 μL/L. Piperitone inhibits the development of newly laid eggs and of neonate larvae, but is less toxic than the crude extract to individuals developing inside the seeds. Piperitone shows the strongest ovicidal activity. All the eggs were aborted at 6.7 μL/L. Piperitone (10 μM) kills all the neonate larvae[1].

Animal Model:Fifty pairs of C. maculatus adults[1]
Dosage:6.7, 10, 16.7 or 33.3 μL/L
Administration:24 hours
Result:Piperiton was more toxic than crude oil because the LC50 recorded was 1.6 μL/L for Piperitone vs. 2.7 μL/L for the crude oil.

PIPERITONE Preparation Products And Raw materials

Raw materials

Sodium bisulfite Eucalyptus oil

Preparation Products

Menthone ISOMENTHONE
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PIPERITONE Suppliers

Americas 1 China 122 France 1 Germany 3 India 7 Japan 3 Spain 1 United Kingdom 5 United States 23 USA 1 Global 167
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Anhui Yunhefei Spice Co., Ltd.
Tel
15755158983
Email
yunhefei@foxmail.com
Country
China
ProdList
36
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from PIPERITONE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
PIPERITONE 89-81-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Hebei Zhanyao Biotechnology Co. Ltd
Product
PIPERITONE 89-81-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-15
Career Henan Chemical Co
Product
PIPERITONE 89-81-6
Price
US $1.00/KG
Min. Order
1IU
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-07

89-81-6, PIPERITONERelated Search:

Androst-5-en-3-ol-7,17-dione acetate QUASSIN VERBENONE Carbenoxolone disodium 7-Keto-dehydroepiandrosterone 7-KETOCHOLESTEROL 18alpha-Glycyrrhetinic acid Glycyrrhizic acid PIPERITONE 18β-Glycyrrhetinic Acid Ammonium Glycyrrhizinate (-)-VERBENONE 2-Cyclohexen-1-one Ammonium glycyrrhizinate trihydrate NSC81576 cholesta-3,5-dien-7-one Androst-5-en-7-one,3beta,17beta-bis(acetyloxy) 7-oxocholest-5-en-3-beta-yl acetate

  • 1-P-MENTHEN-3-ONE
  • 4-ISOPROPYL-1-METHYL-1-CYCLOHEXEN-3-ONE
  • 6-isopropyl-3-methylcyclohex-2-enone
  • P-MENTH-1-EN-3-ONE 92%
  • piperitone,3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one,p-menth-1-en-3-one
  • PIPERITONE(SG)
  • ALPHA-PIPERITONE
  • PARA-MENTH-1-EN-3-ONE
  • 6-Isopropyl-3-methylcyclohex-2-enon
  • PIPERTONE
  • 4-ISOPROPYL-1-METHYL-1-CYCLOHEXEN-3-ONE 92%
  • PIPERITONE WITH GC
  • 3-Methyl-6-isopropyl-2-cyclohexene-1-one
  • p-Mentha-1-ene-3-one
  • 6-Isopropyl-3-methylcyclohexen-2-one
  • 1-p-Menthen-3-one 6-Isopropyl-3-methyl-2-cyclohexen-1-one
  • PIPERITON
  • PIPERITONE
  • P-MENTH-1-EN-3-ONE
  • 1-Methyl-4-isopropyl-1-cyclohexen-3-one
  • 2-Cyclohexen-1-one, 3-methyl-6-(1-methylethyl)-
  • 2-Cyclohexen-1-one,3-methyl-6-(1-methylethyl)-
  • 3-Carvomenthenone
  • Pepper ketones
  • Piperitone (mixture of enantiomers, predominantly (R)-(-)-form)
  • Piperitone (mixture of enantiomers, predominantly (<i>R</i>)-(-)-form)
  • 3-methyl-6-(1-methylethyl)-2-cyclohexen-1-on
  • 3-methyl-6-(1-methylethyl)-2-Cyclohexen-1-one
  • 6-Isopropyl-3-methyl-2-cyclohexen-1-one
  • (-)-Piperitone&gt
  • 94.0%(GC)
  • Piperitone P
  • PIPERITONE USP/EP/BP
  • 6-Isopropyl-3-methyl-2-cyclohexen-1-one predominantly
  • (-)-Piperitone, ≥ 94.0%
  • Verapamil Impurity 10-d6
  • piperitone, 10 mM in DMSO
  • 89-81-6
  • Biochemistry
  • Monocyclic Monoterpenes
  • Terpenes