cholesta-3,5-dien-7-one

Product Name: cholesta-3,5-dien-7-one
CAS No.: 567-72-6
Chemical Name: cholesta-3,5-dien-7-one
Synonyms: CAY10787;cholesta-3,5-dien-7-one;7-Ketocholesta-3,5-diene;Cholesta-3,5-diene-7-one-d7
CBNumber: CB6880301
Molecular Formula: C27H42O
Formula Weight: 382.62
MOL File: 567-72-6.mol

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cholesta-3,5-dien-7-one Property

Melting point:: 114 °C
Boiling point:: 494.0±12.0 °C(Predicted)
Density: 0.99±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Chloroform: 10 mg/ml
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R209902
Product name: CHOLESTA-3,5-DIEN-7-ONE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $179
Updated: 2025/07/31

Sigma-Aldrich

Product number: R209902
Product name: CHOLESTA-3,5-DIEN-7-ONE
Purity: AldrichCPR
Packaging: 1MG
Price: $174
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: SHG0002467
Product name: CHOLESTA-3,5-DIEN-7-ONE
Purity: 95.00%
Packaging: 5MG
Price: $500.95
Updated: 2021/12/16

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cholesta-3,5-dien-7-one Chemical Properties,Usage,Production

Uses

Delta3,5-cholestadien-7-one is an oxysterol and a negative allosteric modulator of GABAA receptors. Delta3,5-cholestadien-7-one reduces GABA-induced currents in HEK cells expressing α1β1γ2 or α4β3γ2 subunit-containing GABAA receptors with IC50 values of 1.5 and 1 μM, respectively. Delta3,5-cholestadien-7-one reduces GABA-induced depolarization of peptidergic and non-peptidergic nociceptors, C-LTMRs, and cold thermosensors in isolated mouse dorsal root ganglion (DRG) neurons[1][2].

References

[1] Hahn M, et al. Cholest-3,5-dien-7-one formation in peroxidized human plasma as an indicator of lipoprotein cholesterol peroxidation potential. Biochim Biophys Acta. 1995 Apr 6;1255(3):341-3. DOI:10.1016/0005-2760(95)00004-v

cholesta-3,5-dien-7-one Preparation Products And Raw materials

Raw materials

Preparation Products

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cholesta-3,5-dien-7-one Suppliers

China 13 India 1 United States 2 Global 16

Clearsynth Labs Limited

Tel: +91-22-26355700
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Country: India
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Nanjing Haolv Biotechnology Co.,Ltd

Tel: 025-84622273 17361806303
Email: kexin.zhou@haolvbiotech.com
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Yancheng Tongming Biotechnology Co., Ltd.

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Country: China
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

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Email: 1033@dideu.com
Country: China
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TargetMol Chemicals Inc.

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Shanghai Saikerui Biotechnology Co. , Ltd.

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Shanghai Yifei Biotechnology Co. , Ltd.

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hubei PharmaStandard Co., Ltd.

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BePure (Beijing) Biotechnology Co.

Tel: 58896805
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Country: CHINA
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cholesta-3,5-dien-7-one

7-Ketocholesta-3,5-diene

Cholesta-3,5-diene-7-one-d7

CAY10787

567-72-6