18alpha-Glycyrrhetinic acid

ChemicalBook > CAS DataBase List > 18alpha-Glycyrrhetinic acid

18alpha-Glycyrrhetinic acid

Chemical Properties Uses

Product Name: 18alpha-Glycyrrhetinic acid
CAS No.: 1449-05-4
Chemical Name: 18alpha-Glycyrrhetinic acid
Synonyms: Nsc 35350;Triterpene;Ccris 3963;Brn 2956366;Einecs 215-907-9;18α-Glycyrrhetinic;18a-Glycyrrhetic acid;18α-Glycyrrhetic acid;18A-GLYCYRRHETINIC ACID;beta-glycyrrhetinicacid
CBNumber: CB7172205
Molecular Formula: C30H46O4
Formula Weight: 470.68
MOL File: 1449-05-4.mol

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18alpha-Glycyrrhetinic acid Property

Melting point:: 331-333°C
Boiling point:: 492.11°C (rough estimate)
Density: 0.9967 (rough estimate)
refractive index: 1.4800 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.71±0.70(Predicted)
color: White to Off-White
LogP: 6.570 (est)
CAS DataBase Reference: 1449-05-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: ection
WGK Germany: 3
RTECS: RK0190000
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G8503
Product name: 18α-Glycyrrhetinic acid
Purity: ≥95%
Packaging: 250mg
Price: $114
Updated: 2024/03/01

Sigma-Aldrich

Product number: G8503
Product name: 18α-Glycyrrhetinic acid
Purity: ≥95%
Packaging: 1g
Price: $254.4
Updated: 2024/03/01

Usbiological

Product number: 412321
Product name: 18α-Glycyrrhetinic Acid
Packaging: 100mg
Price: $460
Updated: 2021/12/16

TRC

Product number: G735005
Product name: 18α-Glycyrrhetinic acid
Packaging: 500mg
Price: $660
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0017607
Product name: 18ALPHA-GLYCYRRHETINIC ACID
Purity: 95.00%
Packaging: 1G
Price: $973.84
Updated: 2021/12/16

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18alpha-Glycyrrhetinic acid Chemical Properties,Usage,Production

Chemical Properties

Glycyrrhetinic acid is a kind of glycoside composed of glycyrrhizic acid-ff two molecules glucuronic acid. It appears as white crystalline powder with sweet taste. The sweetness is about 200 times of the sucrose. Its sweetness is different from other sweeteners such as sucrose. After eating, you can sense the sweetness only after a few moments but the retention time is long. Combination of a small amount of glycyrrhizin and sucrose can save 20% sucrose without affecting the sweetness. Although having no aroma, it has incense effect. It has a melting point (decomposition) of 220 ° C. The aqueous solution is weakly acidic and can be treated by acid.

Uses

Sweeteners; sweetness improving agents; flavor enhancers (dairy products, cocoa products, egg products, mutton), flavoring agents (function well especially when used in combination with salt), Chinese folk mostly use it in sauce and sauce products, pickled goods and so on.

Uses

18α-Glycyrrhetinic acid may be used to synthesize:

3-keto-18α-glycyrrhetinic acid
methyl esters of 18α-glycyrrhetinic acid
methyl esters of 3-keto-18α-glycyrrhetinic acid

General Description

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).

18alpha-Glycyrrhetinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 18alpha-Glycyrrhetinic acid manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.

Product: Glycyrrhetinic acid 1449-05-4 1449-05-4
Price: US $7.50/mg
Min. Order: 20mg
Purity: ≥98%
Supply Ability: 1000.00 kgs
Release date: 2019-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 18alpha-Glycyrrhetinic acid 1449-05-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 18alpha-Glycyrrhetinic acid 1449-05-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

1449-05-4, 18alpha-Glycyrrhetinic acidRelated Search:

5-CAPROLEIC ACID 18alpha-Glycyrrhetinic acid 5-METHYL-2-HEPTEN-4-ONE trans-4-Ethylcyclohexanecarboxylic acid 16-HYDROXYHEXADECANOIC ACID 4-CYCLOHEXYLBUTYRIC ACID Diammonium glycyrrhizinate trans-4-Hexylcyclohexanecarboxylic acid 3,5-Dimethyl-2-cyclohexen-1-one PIPERITONE Celery ketone 15-METHYLHEXADECANOIC ACID 3-Methyl-5-hexyl-2-cyclohexen-1-one Neodecanoic acid 4-BUTYLCYCLOHEXANE CARBOXYLIC ACID Carbenoxolone disodium 18β-Glycyrrhetinic Acid Glycyrrhetinic acid sodium salt

3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicaci

3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicacid

beta-glycyrrhetinicacid

GLYCYRRHETINIC ACID, 18A-

3BETA-HYDROXY-11-OXO-18ALPHA,20BETA-OLEAN-12-EN-29-OIC ACID

18A-GLYCYRRHETINIC ACID

18ALPHA-GLYCYRRHETINIC ACID

Triterpene

Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,18.alpha.,20.beta.)-

(18α)-3β-Hydroxy-11-oxoolean-12-en-30-oic acid

3β-hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid

18-ISOGLYCYRRHETINICACID

18-ALPHA-GLYCYRRHETICACID

(3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid

18α-Glycyrrhetinic

18-alpha-Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-

Brn 2956366

Ccris 3963

Einecs 215-907-9

Nsc 35350

18a-Glycyrrhetic acid

18alpha-Glycyrrhetinic acid >=95%

Glycyrrhetinic acid (α-type)

18α-Glycyrrhetinic acid, 95%, from Glycyrrhiza uralensis Fisch.

Glycyrrhetinic acid 1449-05-4

18a-Glycyrrhetic acid,95%

18α-Glycyrrhetinic Acid,HPLC≥98%

Enoxolone EP Impurity A

Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,18α,20β)-

18α-Glycyrrhetinic Acid

Enoxolone Impurity 1 (Enoxolone EP Impurity A)

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hy droxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3 ,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-ic osahydropicene-2-carboxylic acid

18α-Glycyrrhetic acid

18 α-glycyrrhetintic acid

Magnesium Isoglycyrrhetinic Acid Impurity C

18α-Glycyrrhetinic acid-RM

Glycyrrhetinic Acid18A-(AS)

Glycyrrhetinic Acid Impurity 14

1449-05-4

Chiral Building Blocks

Asymmetric Synthesis

Complex Molecules

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

The group of Liquorice

Tri-Terpenoids