ChemicalBook > CAS DataBase List > 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Product Name
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CAS No.
300827-87-6
Chemical Name
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
Synonyms
D2069;Desvenlafaxine HCl;Venlafaxine Impurity 16;Desvenlafaxine hydrochloride;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CBNumber
CB12101937
Molecular Formula
C16H25NO2HCl
Formula Weight
0
MOL File
300827-87-6.mol
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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Property

Melting point:
>75°C (dec.)
storage temp. 
2-8°C
solubility 
DMSO: >20mg/mL
form 
powder
color 
white to off-white
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D2069
Product name
Desvenlafaxine hydrochloride
Purity
≥98% (HPLC), powder
Packaging
10mg
Price
$233
Updated
2024/03/01
Sigma-Aldrich
Product number
D2069
Product name
Desvenlafaxine hydrochloride
Purity
≥98% (HPLC), powder
Packaging
50mg
Price
$711
Updated
2024/03/01
TRC
Product number
D297928
Product name
Desvenlafaxine hydrochloride
Packaging
50mg
Price
$525
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008432
Product name
DESVENLAFAXINE HYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$713.71
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008432
Product name
DESVENLAFAXINE HYDROCHLORIDE
Purity
95.00%
Packaging
50MG
Price
$1220.03
Updated
2021/12/16
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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Chemical Properties,Usage,Production

Uses

Desvenlafaxine Hydrochloride is a major active metabolite of venlafaxine (V120000), which is a slective serotonin noradrenaline reuptake inhibitor and used as an antidepressant.

Uses

Desvenlafaxine hydrochloride has been used to evaluate if its occurrence in drinking water at environmental concentrations could induce neuronal gene expression.

Biochem/physiol Actions

Desvenlafaxine hydrochloride is a dual SERT/NET reuptake inhibitor. It is a major active metabolite of venlafaxine (#542); brain penetrant; Ki = 40 nM and 122 nM for hSERT and hNET, respectively (weak binding at the hDAT). Inhibition of [3H]5-HT or [3H]NE uptake for the hSERT or hNET produced IC50 values of 47 and 531 nM.

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Suppliers

China 14 India 1 Switzerland 1 United States 7 Global 23
SIGMA-RBI
Tel
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Fax
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Switzerland
ProdList
6896
Advantage
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300827-87-6, 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochlorideRelated Search:

1-[2-(DiMethyloxidoaMino)-1-(4-Methoxyphenyl)ethyl]cyclohexanol rac N-DesMethyl-N-(4-Methoxyphenethyl) Venlafaxine 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride ethyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate hydrochloride Venlafaxine N-Dimer (5RS)-5-(4-Methoxyphenyl)-3-Methyl-1-oxa-3-azaspiro-[5.5]undecane Hydrochloride Venlafaxine Related Compound A (10 mg) (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride) D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine (2RS)-2-(Cyclohex-1-enyl)-2-(4-Methoxyphenyl)-N,N-diMethylethanaMine Hydrochloride (2RS)-2-Cyclohexyl-2-(4-Methoxyphenyl)-N,NdiMethylethanaMineHydrochloride Venlafaxine hydrochloride

  • 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
  • Desvenlafaxine hydrochloride
  • D2069
  • Venlafaxine Impurity 16
  • Desvenlafaxine HCl
  • 300827-87-6