(3-bromopyridin-2-yl)methanol
- Product Name
- (3-bromopyridin-2-yl)methanol
- CAS No.
- 52378-64-0
- Chemical Name
- (3-bromopyridin-2-yl)methanol
- Synonyms
- 3-Bromopyridine-2-methanol;3-BroMo-2-pyridineMethanol;(3-bromo-2-pyridyl)methanol;2-PyridineMethanol, 3-broMo-;(3-bromopyridin-2-yl)methanol;3-Bromo-2-hydroxymethylpyridine;2-Hydroxymethyl-3-bromopyridine;3-Bromo pyridine-2-yl) methanol;(3-bromopyridin-2-yl)methanol ISO 9001：2015 REACH;(3-Bromopyridin-2-yl)methanol, 3-Bromo-alpha-hydroxy-2-picoline
- CBNumber
- CB12106109
- Molecular Formula
- C6H6BrNO
- Formula Weight
- 188.02
- MOL File
- 52378-64-0.mol
(3-bromopyridin-2-yl)methanol Property
- Boiling point:
- 260.9±25.0 °C(Predicted)
- Density
- 1.668±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- pka
- 12.75±0.10(Predicted)
- Appearance
- Off-white to brown Solid
- InChI
- InChI=1S/C6H6BrNO/c7-5-2-1-3-8-6(5)4-9/h1-3,9H,4H2
- InChIKey
- FTTLCYCJDYIEFO-UHFFFAOYSA-N
- SMILES
- C1(CO)=NC=CC=C1Br
Safety
- RIDADR
- UN2811
- HS Code
- 2933399990
N-Bromosuccinimide Price
- Product number
- B696205
- Product name
- 3-Bromo-2-hydroxymethylpyridine
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB153803
- Product name
- (3-Bromopyridin-2-yl)methanol
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 4H01-9-X2
- Product name
- 3-Bromo-2-(hydroxymethyl)pyridine
- Packaging
- 100mg
- Price
- $107
- Updated
- 2021/12/16
- Product number
- FB153803
- Product name
- (3-Bromopyridin-2-yl)methanol
- Packaging
- 500mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- W6721
- Product name
- (3-Bromopyridin-2-yl)methanol
- Packaging
- 1g
- Price
- $169
- Updated
- 2021/12/16
(3-bromopyridin-2-yl)methanol Chemical Properties,Usage,Production
Chemical Properties
(3-bromopyridin-2-yl)methanol is a solid,it is stable under recommended temperatures and pressures.It can react with strong oxidizing agents.
Uses
(3-bromopyridin-2-yl)methanol is commonly used as an intermediate in organic and pharmaceutical synthesis.
Uses
(3-bromopyridin-2-yl)methanol is commonly used as an intermediate in organic and pharmaceutical synthesis.
Hazard
(3-bromopyridin-2-yl)methanol is toxicity if swallowed. Skin contact with it may result in inflammation characterized by itching, scaling, reddening, blistering, pain or dryness. Eye contact may result in redness, pain or severe eye damage.
Synthesis
405174-97-2
52378-64-0
General procedure for the synthesis of 3-bromo-2-hydroxymethylpyridine from 3-bromopyridine-2-carboxaldehyde: Preparation of (3-bromopyridin-2-yl)methanol (B5.2) (0363): 3-bromopyridine-2-carboxaldehyde (B5.1) (1 g, 5.4 mmol) was dissolved in a mixture of solvents of MeOH (20 mL) and THF (10 mL) and cooled to 0 °C. NaBH4 (0.82 g, 21.6 mmol) was added in batches under stirring. The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 hours. Upon completion of the reaction, the mixture was concentrated to remove most of the solvent and subsequently diluted with deionized water (40 mL). Extraction was carried out with dichloromethane (DCM, 40 mL x 3) and the organic layers were combined and washed with saturated brine. The organic layer was dried over anhydrous Na2SO4, filtered and concentrated to afford the target product 3-bromo-2-hydroxymethylpyridine (1 g, 99% yield) as a white solid.LC-MS detection: [M + H]+ = 190.0.
References
[1] Patent: US2016/176882, 2016, A1. Location in patent: Paragraph 0361; 0363
[2] Patent: WO2017/221100, 2017, A1. Location in patent: Paragraph 00171
[3] Patent: WO2017/221092, 2017, A1. Location in patent: Paragraph 00169
(3-bromopyridin-2-yl)methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(3-bromopyridin-2-yl)methanol Suppliers
- Tel
- +86-024-83607930; 18640359690
- Fax
- 024-83607930
- sales@honghuchem.com
- Country
- China
- ProdList
- 256
- Advantage
- 58
- Tel
- 86-0531-68658065 15726150375
- Fax
- 0531-68658065
- 1071018499@qq.com
- Country
- China
- ProdList
- 526
- Advantage
- 58
- Tel
- 0418-5113999 18740177324
- Fax
- 2851606178
- sales@custchem.com.cn
- Country
- China
- ProdList
- 441
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2806
- Advantage
- 65
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
View Lastest Price from (3-bromopyridin-2-yl)methanol manufacturers
- Product
- (3-bromopyridin-2-yl)methanol 52378-64-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-04
- Product
- (3-bromopyridin-2-yl)methanol 52378-64-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- (3-bromopyridin-2-yl)methanol 52378-64-0
- Price
- US $3.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-26