ESTETROL
- Product Name
- ESTETROL
- CAS No.
- 15183-37-6
- Chemical Name
- ESTETROL
- Synonyms
- E 4;UBE4A;Donesta;ESTETROL;KIAA0126;MGC133315;15α-Hydroxyestriol;15a-Hydroxyestriol;15-ALPHA-HYDROXYESTRIOL;Estra-1,3,5(10)-triene-3,15a,16a,17-tetrol
- CBNumber
- CB1210710
- Molecular Formula
- C18H24O4
- Formula Weight
- 304.38
- MOL File
- 15183-37-6.mol
ESTETROL Property
- Melting point:
- 233-236°C
- Boiling point:
- 491.9±45.0 °C(Predicted)
- Density
- 1.343±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO: soluble20mg/mL, clear
- pka
- 10.22±0.70(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +125 to +135, c = 1 in ethanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML1523
- Product name
- Estetrol
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $219
- Updated
- 2024/03/01
- Product number
- SML1523
- Product name
- Estetrol
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $870
- Updated
- 2024/03/01
- Product number
- 18232
- Product name
- Estetrol
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 18232
- Product name
- Estetrol
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $63
- Updated
- 2021/12/16
- Product number
- 18232
- Product name
- Estetrol
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $158
- Updated
- 2021/12/16
ESTETROL Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol and estriol during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium). In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.
Uses
A metabolite of Estradiol. It is an estrogenic steroid synthesized exclusively by the fetal liver during human pregnancy and reaching the maternal circulation through the placenta.
Definition
ChEBI: Estetrol is a 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. It has a role as an estrogen, an estrogen receptor agonist, a human metabolite, a human xenobiotic metabolite and an oral contraceptive. It is a 3-hydroxy steroid, a 17beta-hydroxy steroid, a 16alpha-hydroxy steroid, a 15alpha-hydroxy steroid and a steroid hormone. It derives from a hydride of an estrane.
ESTETROL Preparation Products And Raw materials
Raw materials
Preparation Products
ESTETROL Suppliers
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