PENTAETHYLENE GLYCOL MONOMETHYL ETHER

Product Name: PENTAETHYLENE GLYCOL MONOMETHYL ETHER
CAS No.: 23778-52-1
Chemical Name: PENTAETHYLENE GLYCOL MONOMETHYL ETHER
Synonyms: 2,5,8,11,14-Pentaoxahexadecan-16-ol;MPEG-5;MPEG5-OH;MPEG11-NH2;m-PEG5-alcohol;HO-(CH2CH2O)5-Me;Methyl-PEG5-alcohol;2,5,8,11,14,17,20,23;3,6,9,12,15-pentaoxahexadecenol;3,6,9,12,15-Pentaoxahexadecanol
CBNumber: CB1211919
Molecular Formula: C11H24O6
Formula Weight: 252.3
MOL File: 23778-52-1.mol

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PENTAETHYLENE GLYCOL MONOMETHYL ETHER Property

Boiling point:: 110 °C(Press: 0.01 Torr)
Density: 1.08
refractive index: 1.4480 to 1.4520
storage temp.: -20°C
form: clear liquid
pka: 14.36±0.10(Predicted)
color: Colorless to Light yellow to Light orange
InChI: InChI=1S/C11H24O6/c1-13-4-5-15-8-9-17-11-10-16-7-6-14-3-2-12/h12H,2-11H2,1H3
InChIKey: SLNYBUIEAMRFSZ-UHFFFAOYSA-N
SMILES: C(O)COCCOCCOCCOCCOC
CAS DataBase Reference: 23778-52-1
EPA Substance Registry System: 2,5,8,11,14-Pentaoxahexadecan-16-ol (23778-52-1)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2909.49.6000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P1159
Product name: Pentaethylene Glycol Monomethyl Ether
Purity: >96.0%(GC)
Packaging: 1g
Price: $158
Updated: 2025/07/31

TCI Chemical

Product number: P1159
Product name: Pentaethylene Glycol Monomethyl Ether
Purity: >96.0%(GC)
Packaging: 5g
Price: $517
Updated: 2025/07/31

AK Scientific

Product number: AMTGC304
Product name: 2,5,8,11,14-Pentaoxahexadecan-16-ol
Packaging: 10g
Price: $445
Updated: 2021/12/16

chempep

Product number: 281209
Product name: mPEG11-NH2
Purity: >=95%
Packaging: 1g
Price: $555
Updated: 2021/12/16

Chem-Impex

Product number: 41726
Product name: Pentaethyleneglycolmonomethylether,≥96%(GC)
Purity: ≥96%(GC)
Packaging: 5G
Price: $625.5
Updated: 2021/12/16

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PENTAETHYLENE GLYCOL MONOMETHYL ETHER Chemical Properties,Usage,Production

Description

m-PEG5-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Synthesis

112-60-7

6482-24-2

23778-52-1

The general procedure for the synthesis of pentaethylene glycol monomethyl ether from tetraethylene glycol truncated and 2-bromoethyl methyl ether was as follows: tetraethylene glycol (55 mmol, 10.7 g) was dissolved in 100 mL of tetrahydrofuran (THF), and potassium tert-butoxide (KOtBu, 55 mL, 1.0 M solution in THF) was added to this solution at room temperature. The resulting mixture was stirred at room temperature for 30 min, followed by the slow dropwise addition of 2-bromoethyl methyl ether (55 mmol, 5.17 mL, dissolved in 50 mL THF). The reaction mixture was stirred overnight at room temperature and then extracted with 300 mL of water and 3 x 300 mL of dichloromethane. The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). The desiccant was removed by filtration and after evaporation of the solvent, the crude product was purified using silica gel column chromatography (eluent ratio CH2Cl2:CH3OH = 60:140:1) to afford pure pentaethylene glycol monomethyl ether (35% yield).1H NMR (CDCl3) δ 3.75-3.42 (m, 20H, OCH2CH2O), 3.39 (s, 3H MeO).

IC 50

PEGs

References

[1] Patent: US2005/136031, 2005, A1. Location in patent: Page/Page column 25

PENTAETHYLENE GLYCOL MONOMETHYL ETHER Preparation Products And Raw materials

Raw materials

Preparation Products

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PENTAETHYLENE GLYCOL MONOMETHYL ETHER Suppliers

Americas 1 China 164 Europe 1 Germany 1 India 2 Japan 1 United Kingdom 3 United States 15 Global 188

Changzhou green chemical co., LTD

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Energy Chemical

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Accela ChemBio Co.,Ltd.

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View Lastest Price from PENTAETHYLENE GLYCOL MONOMETHYL ETHER manufacturers

LAURENT

Product: mPEG5-OH 23778-52-1
Price: US $3458.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 500kg
Release date: 2025-11-20

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG5-alcohol 23778-52-1
Price: US $0.00/g
Min. Order: 100g
Purity: >98.00%
Supply Ability: 100g
Release date: 2024-03-27

Career Henan Chemical Co

Product: (10-Phenyl-9-anthracenyl)boronic acid pinacol ester 23778-52-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

23778-52-1, PENTAETHYLENE GLYCOL MONOMETHYL ETHERRelated Search:

PENTAETHYLENE GLYCOL m-PEG5-bromide 2,5,8,11,14-pentaoxahexadecan-16-oic acid 2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL PENTAETHYLENEHEXAMINE PENTAETHYLENE GLYCOL MONOHEXADECYL ETHER HEXAETHYLENE GLYCOL MONOHEXADECYL ETHER HEXAETHYLENE GLYCOL MONODECYL ETHER C14E6 Dicyclohexano-24-crown-8 (+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID HEPTAETHYLENE GLYCOL MONODODECYL ETHER POLYOXYETHYLENE 5 STEARYL ETHER C12E5 Dicyclohexano-18-crown-6 HEXAETHYLENE GLYCOL DIMETHYL ETHER HEXAETHYLENE GLYCOL MONODODECYL ETHER Hexaethylene glycol

PENTAETHYLENE GLYCOL MONOMETHYL ETHER

2,5,8,11,14-Pentaoxahexadecan-16-ol

2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol

3,6,9,12,15-Pentaoxahexadecanol

PENTAETHYLENE GLYCOL MONOMETHYL ETHER 96+%

POLYETHYLENEGLYCOLMONOMETHYLETHER(N=5)

3,6,9,12,15-pentaoxahexadecenol

2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-aMine

MPEG11-NH2

MPEG5-OH

MPEG-5

3,6,9,12,15-Pentaoxahexadecan-1-ol

m-PEG5-alcohol

Methyl-PEG5-alcohol

2,5,8,11,14,17,20,23

PentaethyleneGlycolMonomethylEther&gt

PENTAETHYLENE GLYCOL MONOMETHYL ETHER ISO 9001：2015 REACH

HO-(CH2CH2O)5-Me

mPEG5-OH/3,6,9,12,15-Pentaoxahexadecan-1-ol

PENTAETHYLENE GLYCOL MONOMETHYL ETHE

23778-52-1

C11H24O6

Monofunctional Ethylene Glycols

Ethylene Glycols & Monofunctional Ethylene Glycols

Monofunctional Ethylene Glycols

PEG-COOH

peg