PENTAETHYLENE GLYCOL MONOMETHYL ETHER
- Product Name
- PENTAETHYLENE GLYCOL MONOMETHYL ETHER
- CAS No.
- 23778-52-1
- Chemical Name
- PENTAETHYLENE GLYCOL MONOMETHYL ETHER
- Synonyms
- 2,5,8,11,14-Pentaoxahexadecan-16-ol;MPEG-5;MPEG5-OH;MPEG11-NH2;m-PEG5-alcohol;HO-(CH2CH2O)5-Me;Methyl-PEG5-alcohol;2,5,8,11,14,17,20,23;3,6,9,12,15-pentaoxahexadecenol;3,6,9,12,15-Pentaoxahexadecanol
- CBNumber
- CB1211919
- Molecular Formula
- C11H24O6
- Formula Weight
- 252.3
- MOL File
- 23778-52-1.mol
PENTAETHYLENE GLYCOL MONOMETHYL ETHER Property
- Boiling point:
- 110 °C(Press: 0.01 Torr)
- Density
- 1.08
- refractive index
- 1.4480 to 1.4520
- storage temp.
- -20°C
- form
- clear liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to Light yellow to Light orange
- InChI
- InChI=1S/C11H24O6/c1-13-4-5-15-8-9-17-11-10-16-7-6-14-3-2-12/h12H,2-11H2,1H3
- InChIKey
- SLNYBUIEAMRFSZ-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCOCCOCCOC
- CAS DataBase Reference
- 23778-52-1
- EPA Substance Registry System
- 2,5,8,11,14-Pentaoxahexadecan-16-ol (23778-52-1)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 2909.49.6000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- P1159
- Product name
- Pentaethylene Glycol Monomethyl Ether
- Purity
- >96.0%(GC)
- Packaging
- 1g
- Price
- $158
- Updated
- 2025/07/31
- Product number
- P1159
- Product name
- Pentaethylene Glycol Monomethyl Ether
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $517
- Updated
- 2025/07/31
- Product number
- 41726
- Product name
- Pentaethyleneglycolmonomethylether,≥96%(GC)
- Purity
- ≥96%(GC)
- Packaging
- 1G
- Price
- $171.23
- Updated
- 2021/12/16
- Product number
- BP-22068
- Product name
- m-PEG5-alcohol
- Purity
- 98%
- Packaging
- 5G
- Price
- $180
- Updated
- 2021/12/16
- Product number
- BP-22068
- Product name
- m-PEG5-alcohol
- Purity
- 98%
- Packaging
- 10g
- Price
- $315
- Updated
- 2021/12/16
PENTAETHYLENE GLYCOL MONOMETHYL ETHER Chemical Properties,Usage,Production
Description
m-PEG5-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization
Synthesis
112-60-7
6482-24-2
23778-52-1
The general procedure for the synthesis of pentaethylene glycol monomethyl ether from tetraethylene glycol truncated and 2-bromoethyl methyl ether was as follows: tetraethylene glycol (55 mmol, 10.7 g) was dissolved in 100 mL of tetrahydrofuran (THF), and potassium tert-butoxide (KOtBu, 55 mL, 1.0 M solution in THF) was added to this solution at room temperature. The resulting mixture was stirred at room temperature for 30 min, followed by the slow dropwise addition of 2-bromoethyl methyl ether (55 mmol, 5.17 mL, dissolved in 50 mL THF). The reaction mixture was stirred overnight at room temperature and then extracted with 300 mL of water and 3 x 300 mL of dichloromethane. The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). The desiccant was removed by filtration and after evaporation of the solvent, the crude product was purified using silica gel column chromatography (eluent ratio CH2Cl2:CH3OH = 60:140:1) to afford pure pentaethylene glycol monomethyl ether (35% yield).1H NMR (CDCl3) δ 3.75-3.42 (m, 20H, OCH2CH2O), 3.39 (s, 3H MeO).
IC 50
PEGs
References
[1] Patent: US2005/136031, 2005, A1. Location in patent: Page/Page column 25
PENTAETHYLENE GLYCOL MONOMETHYL ETHER Preparation Products And Raw materials
Raw materials
Preparation Products
PENTAETHYLENE GLYCOL MONOMETHYL ETHER Suppliers
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View Lastest Price from PENTAETHYLENE GLYCOL MONOMETHYL ETHER manufacturers
- Product
- mPEG5-OH 23778-52-1
- Price
- US $3458.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2025-11-20
- Product
- m-PEG5-alcohol 23778-52-1
- Price
- US $0.00/g
- Min. Order
- 100g
- Purity
- >98.00%
- Supply Ability
- 100g
- Release date
- 2024-03-27
- Product
- (10-Phenyl-9-anthracenyl)boronic acid pinacol ester 23778-52-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-09