(2-amino-3-hydroxy-octadecoxy)phosphonic acid

Product Name: (2-amino-3-hydroxy-octadecoxy)phosphonic acid
CAS No.: 19794-97-9
Chemical Name: (2-amino-3-hydroxy-octadecoxy)phosphonic acid
Synonyms: 2S-amino-1;SPHINGANINE-1-PHOSPHATE;dihydrosphingosine 1-phosphate;(2S,3R)-Sphinganine 1-Phosphate;Sphinganine-1-phosphate (d18:0);D-erythro-sphinganine-1-phosphate;C18-Dihydrosphingosine 1-Phosphate;(2-amino-3-hydroxy-octadecoxy)phosphonic acid;D-erythro-Dihydrosphingosine 1-phosphate;(2S,3R)-2-AMino-1,3-octadecanediol 1-(Dihydrogen Phosphate)
CBNumber: CB12129494
Molecular Formula: C18H40NO5P
Formula Weight: 381.49
MOL File: 19794-97-9.mol

More

Less

(2-amino-3-hydroxy-octadecoxy)phosphonic acid Property

Boiling point:: 548.2±60.0 °C(Predicted)
Density: 1.080±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: 0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; Ethanol: <50 μg/ml; PBS (pH 7.2): <50 μg/ml
form: A crystalline solid
pka: 1.76±0.10(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3439
Product name: <SC>D</SC>-<I>erythro</I>-Dihydrosphingosine 1-phosphate
Purity: ≥98% (TLC), waxy solid
Packaging: 1mg
Price: $282
Updated: 2025/07/31

Cayman Chemical

Product number: 22500
Product name: Sphinganine-1-phosphate (d18:0)
Purity: ≥95%
Packaging: 500μg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 22500
Product name: Sphinganine-1-phosphate (d18:0)
Purity: ≥95%
Packaging: 1mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 22500
Product name: Sphinganine-1-phosphate (d18:0)
Purity: ≥95%
Packaging: 5mg
Price: $419
Updated: 2024/03/01

TRC

Product number: D449500
Product name: D-erythro-Dihydro-D-sphingosine-1-phosphate
Packaging: 2mg
Price: $135
Updated: 2021/12/16

More

Less

(2-amino-3-hydroxy-octadecoxy)phosphonic acid Chemical Properties,Usage,Production

Chemical Properties

White to Beige Solid

Uses

(2-amino-3-hydroxy-octadecoxy)phosphonic acid may be used as a negative control for C2 Ceramide.

Definition

ChEBI: A sphingoid 1-phosphate that is the monophosphorylated derivative of sphinganine.

Biochem/physiol Actions

Negative control for sphingosine-1-phosphate.

in vivo

Sphinganine 1-phosphate can enhance wound healing in diabetic mice^[1]. Sphinganine 1-phosphate provides renal and hepatic protection after liver ischemia and reperfusion (IR) injury in mice through selective activation of S1P1 receptors and pertussis toxin-sensitive G-proteins with subsequent activation of ERK and Akt. Sphinganine 1-phosphate (administered 0.1 mg/kg i.v. immediately before reperfusion and 0.2 mg/kg s.c. 2 h after reperfusion) protects against hepatic and renal injury after liver IR^[2].

Animal Model:	Male C57BL/6 mice (20-25?g)^[2]
Dosage:	0.1?mg/kg
Administration:	Administered i.v. immediately before reperfusion and 0.2?mg/kg s.c. 2 h after reperfusion
Result:	The plasma level of alanine aminotransferase (ALT) and Creatinine (Cr) was 80±6 U/L and 0.46±0.05 mg/dL, respectively. The increases in ALT (7474±557?U/L) and Cr (0.55±0.05?mg/dL) were significantly suppressed at 24?h after reperfusion in mice treated with 0.1?mg/kg i.v. before reperfusion and 0.2?mg/kg s.c. 2?h after reperfusion.

IC 50

Human Endogenous Metabolite

(2-amino-3-hydroxy-octadecoxy)phosphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(2-amino-3-hydroxy-octadecoxy)phosphonic acid Suppliers

Canada 1 China 32 India 1 United States 2 USA 1 Global 37

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Yichang Zhongyitai Trading Co., Ltd.

Tel: 0717-6449896 13886658719
Fax: 0717-6558598
Email: root@zhongyitai.com
Country: China
ProdList: 1978
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Uteam Biotechnology Co., Ltd.

Tel: 021-36031160 13311776681
Email: 3338195766@QQ.com
Country: China
ProdList: 5093
Advantage: 55

Shanghai Biological Technology Development Co., Ltd.

Tel: 021-69955236-807 13918189704
Fax: 021-65211385
Email: chinaruji@chinaruji.com
Country: China
ProdList: 5095
Advantage: 55

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

Foshan Treasure Biotechnology Co., Ltd

Tel: 0757-85921206 18520245316
Email: 2329783215@qq.com
Country: China
ProdList: 12661
Advantage: 58

amyjetsci

Tel: 027-59626688 18771149750
Email: sales@amyjet.com
Country: China
ProdList: 2917
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Hubei Aiputi Bioengineering Co., Ltd.

Tel: 17762444226
Email: d17762444226@163.com
Country: China
ProdList: 2402
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 18003
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81136151 17392212881
Email: 1095@dideu.com
Country: China
ProdList: 9984
Advantage: 58

SHANGHAI ZZBIO CO., LTD.

Tel: 15102117276 19921389125
Email: tech@zzbioco.com
Country: China
ProdList: 12064
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Guangzhou Lucheng Biotechnology Co., Ltd.

Tel: 16620452357
Country: CHINA
ProdList: 0
Advantage: 58

Guangzhou Junze Biotechnology Co., Ltd.

Tel: 17688489295
Country: CHINA
ProdList: 188
Advantage: 58

Guangdong Zijinggang Technology Co., Ltd.

Tel: 13128698830
Country: CHINA
ProdList: 179
Advantage: 58

Beijing Pubiao Technology Co., Ltd.

Tel: 18618179058
Country: CHINA
ProdList: 122
Advantage: 58

Xingwang Biotechnology Co., Ltd. (Ruijing Testing Company, please do not buy)

Tel: 15017521343
Country: CHINA
ProdList: 186
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

19794-97-9, (2-amino-3-hydroxy-octadecoxy)phosphonic acidRelated Search:

(2-amino-3-hydroxy-octadecoxy)phosphonic acid 6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE TNPAL-SPHINGOMYELIN BODIPY(R) FL C12-SPHINGOMYELIN

SPHINGANINE-1-PHOSPHATE

(2-amino-3-hydroxy-octadecoxy)phosphonic acid

dihydrosphingosine 1-phosphate

D-erythro-sphinganine-1-phosphate

(2S,3R)-2-AMino-1,3-octadecanediol 1-(Dihydrogen Phosphate)

(2S,3R)-Sphinganine 1-Phosphate

[R-(R*,S*)]-2-AMino-1,3-octadecanediol 1-(Dihydrogen Phosphate)

C18-Dihydrosphingosine 1-Phosphate

Sphinganine-1-phosphate (d18:0)

1,3-Octadecanediol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R)-

2S-amino-1

D-erythro-Dihydrosphingosine-1-phosphate, sphingosine 1-phosphate receptor ligand

<sc>D</sc>-<i>erythro</i>-Dihydrosphingosine 1-phosphate

19794-97-9