9-Hydroxycamptothecin

Product Name: 9-Hydroxycamptothecin
CAS No.: 67656-30-8
Chemical Name: 9-Hydroxycamptothecin
Synonyms: 10-Hydroxycamptothecin;9-Hydroxycamptothecine;Hydroxycampothecin;9-Hydroxycamptothecin;10-Hydroxycampothecin;Campathecin Impurity 17;10-HYDROXY CAMPTOTHECINE;Hydroxyl camptothecine USP/EP/BP;2-[methyl(propyl)amino]azobenzamide;4-Ethyl-4,10-dihydroxy-1H-pyrano3',4'
CBNumber: CB12129661
Molecular Formula: C20H16N2O5
Formula Weight: 364.35
MOL File: 67656-30-8.mol

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9-Hydroxycamptothecin Property

Melting point:: 224 °C
Boiling point:: 820.7±65.0 °C(Predicted)
Density: 1.60±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form: Solid
pka: 8.57±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Usbiological

Product number: 299788
Product name: 10-Hydroxycamptothecin
Packaging: 20mg
Price: $280
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb593688
Product name: 10-Hydroxycamptothecin
Packaging: 20mg
Price: $306
Updated: 2021/12/16

ChemScene

Product number: CS-0009109
Product name: 9-Hydroxycamptothecin
Purity: 98.13%
Packaging: 5mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-0009109
Product name: 9-Hydroxycamptothecin
Purity: 98.13%
Packaging: 10mg
Price: $90
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18433
Product name: 10-Hydroxycamptothecin
Packaging: 5mg
Price: $950
Updated: 2021/12/16

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9-Hydroxycamptothecin Chemical Properties,Usage,Production

Uses

9-Hydroxycamptothecin is a camptothecin derivative with anticancer activity, mainly used in drug development and experimental research.

Synthesis

86639-48-7

67656-30-8

Example 3: Preparation of 10-hydroxycamptothecin The camptothecin nitride (500 mg, 1.37 mmol) prepared in Example 1 (A) was dissolved in a mixed dioxane-acetonitrile-water solvent (5:4:1, 500 mL, by volume). Concentrated sulfuric acid (1 mL) was added to this solution and the reaction was subsequently carried out under light conditions for 90 min. After completion of the reaction, the mixture was concentrated under reduced pressure and diluted with deionized water (1 L). The precipitate was collected by filtration and dried to give the crude product. The crude product was washed with methanol and purified by silica gel column chromatography, resulting in 441 mg of 10-hydroxycamptothecin in 88.2% yield. The obtained product was compared with the standard isolated from the hi-tree (Camptotheca acuminata Nyssaceae) by various spectral analysis methods to confirm its structure.

References

[1] Patent: US4473692, 1984, A

9-Hydroxycamptothecin Preparation Products And Raw materials

Raw materials

Preparation Products

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9-Hydroxycamptothecin Suppliers

China 104 India 2 United States 3 Global 109

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Biocompounds Pharmaceutical Inc.

Tel: 21-57687675
Fax: +86-21-57687169
Email: yanjie@biocompounds.com
Country: China
ProdList: 75
Advantage: 62

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

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View Lastest Price from 9-Hydroxycamptothecin manufacturers

Career Henan Chemical Co

Product: 4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 67656-30-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

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10-HYDROXY CAMPTOTHECINE

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Hydroxycampothecin

1H-Pyrano(3',4':6,7)indolizino(1,2-B)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,10-dihydroxy-, (S)-

9-Hydroxycamptothecin

9-Hydroxycamptothecine

4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione###10-Hydroxycamptothecin

(4S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-3,14(4H,12H)-dione

4-Ethyl-4,10-dihydroxy-1H-pyrano3',4'

2-[methyl(propyl)amino]azobenzamide

Hydroxyl camptothecine USP/EP/BP

S-4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dion

(S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Campathecin Impurity 17

67656-30-8

19685-89-7

Herb extract

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract