Glutathione Ethyl Ester

Product Name: Glutathione Ethyl Ester
CAS No.: 92614-59-0
Chemical Name: Glutathione Ethyl Ester
Synonyms: GSH monoethylester;L-αGlu-L-Cys-Gly-OEt;H-GLU(CYS-GLY-OET)-OH;Glutathione Ethyl Ester;L-αGlu-L-Cys-Gly-Ethyl OH;γ-Glu-Cys-Gly-OEt, GSH-MEE;GLUTATHIONE MON ETHYL ESTER;Glutatione Reduced Ethyl Ester;GLUTATHIONE REDUCED FORM, ETHYL ESTE;Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester
CBNumber: CB12130580
Molecular Formula: C12H21N3O6S
Formula Weight: 335.38
MOL File: 92614-59-0.mol

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Glutathione Ethyl Ester Property

Boiling point:: 644.3±55.0 °C(Predicted)
Density: 1.314±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
form: A crystalline solid
pka: 2.21±0.10(Predicted)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G1404
Product name: Glutathione reduced ethyl ester
Purity: ≥90% (TLC)
Packaging: 25mg
Price: $80.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: G1404
Product name: Glutathione reduced ethyl ester
Purity: ≥90% (TLC)
Packaging: 100mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 14953
Product name: Glutathione ethyl ester
Purity: ≥95%
Packaging: 50mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 14953
Product name: Glutathione ethyl ester
Purity: ≥95%
Packaging: 100mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 14953
Product name: Glutathione ethyl ester
Purity: ≥95%
Packaging: 500mg
Price: $350
Updated: 2024/03/01

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Glutathione Ethyl Ester Chemical Properties,Usage,Production

Description

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Uses

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Uses

Glutathione reduced ethyl ester has been used:

to increase intracellular glutathione levels in mouse fibroblast L929 cells
as a medium supplement in Spodoptera frugiperda (Sf)9 cells
to evaluate its effect on lipid peroxidation after spinal cord injury

Biochem/physiol Actions

Glutathione reduced ethyl ester (GSH-MEE) is a membrane/lipid permeable derivative of GSH that may be used to partially supplement the GSH supply within cells subjected to cysteine and/or GSH depletion. GSH-MEE is hydrolysed by intracellular esterases to release GSH, thereby increases the concentrations of intracellular GSH. It prevents the toxic effects of acetaminophen in animal cells. It protects human lymphoid cells and skin fibroblasts against the damage caused due to radiation.

Glutathione Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Glutathione Ethyl Ester Suppliers

China 56 Switzerland 2 United States 3 Global 61

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View Lastest Price from Glutathione Ethyl Ester manufacturers

Hebei Kingfiner Technology Development Co.Ltd

Product: Glutatione Reduced Ethyl Ester 92614-59-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 50000kg
Release date: 2023-11-03

92614-59-0, Glutathione Ethyl EsterRelated Search:

CYS-GLY

H-GLU(CYS-GLY-OET)-OH

Glutathione Ethyl Ester

γ-Glu-Cys-Gly-OEt, GSH-MEE

GSH monoethylester

L-αGlu-L-Cys-Gly-Ethyl OH

L-αGlu-L-Cys-Gly-OEt

Glycine, L-gamma-glutamyl-L-cysteinyl-, 3-ethyl ester

GLUTATHIONE REDUCED FORM, ETHYL ESTE

L-gamma-Glutamyl-L-cysteinylglycine 3-ethyl ester

Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester

Glutathione-monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH

GLUTATHIONE MON ETHYL ESTER

Glutatione Reduced Ethyl Ester

92614-59-0