ChemicalBook > CAS DataBase List > METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE

Product Name: METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE
CAS No.: 653589-95-8
Chemical Name: METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE
Synonyms: Methyl 2-(4;Methyl 2-((4,4;2-METHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER;2-(Methoxycarbonyl)benzeneboronic acid, pinacol ester;N-Methyltetrahydrothiophene-3-amine-1,1-dioxidehydrochloride;METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE;methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoa...;3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate;2-(2-Methoxycarbonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;Methyl 2-((4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)Methyl)benzoate
CBNumber: CB1213120
Molecular Formula: C14H19BO4
Formula Weight: 262.11
MOL File: 653589-95-8.mol

Less

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE Property

Melting point:: 49-51°C
Boiling point:: 363.7±25.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to lump to clear liquid
color: White or Colorless to Almost white or Almost colorless
CAS DataBase Reference: 653589-95-8(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
WGK Germany: 3
HS Code: 2931900090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BML00048
Product name: 2-Methoxycarbonylphenylboronic acid, pinacol ester
Purity: Aldrich
Packaging: 1g
Price: $73.1
Updated: 2025/07/31

TCI Chemical

Product number: M3233
Product name: Methyl 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
Packaging: 1G
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: M3233
Product name: Methyl 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
Packaging: 5G
Price: $90
Updated: 2025/07/31

TRC

Product number: M329685
Product name: 2-Methoxycarbonylphenylboronic acid, pinacol ester
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: AMTB1132
Product name: 2-Methoxycarbonylphenylboronic acid, pinacol ester
Packaging: 1g
Price: $19
Updated: 2021/12/16

Less

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

610-94-6

73183-34-3

653589-95-8

Methyl o-bromobenzoate (2.15 g, 10 mmol), bis(pinacolato)diboron (3.05 g, 12 mmol), potassium acetate (3.92 g, 40 mmol), and [1,1'-bis(diphenylphosphino)ferrocene]palladium dichloride (0.49 g, 0.5 mmol) were sequentially added to 150 mL of dioxane under nitrogen atmosphere. The reaction mixture was heated to 85 °C and the reaction was stirred at this temperature for 12 hours. Upon completion of the reaction, the solvent dioxane was removed by distillation under reduced pressure. The residue was extracted with dichloromethane and the combined organic phases were washed three times with saturated aqueous sodium chloride solution. The organic phases were dried over anhydrous sodium sulfate and the dichloromethane was removed by distillation under reduced pressure to give the crude product. The crude product was purified by column chromatography, and the eluent was a mixed solvent of petroleum ether and dichloromethane (3:1, v/v) to give 2-methoxycarbonylphenylboronic acid pinacol ester as a white solid (1.25 g, 86% yield). The structure of the product was confirmed by 1H NMR, 13C NMR, mass spectrometry (MS) and elemental analysis.

References

[1] Patent: CN108424344, 2018, A. Location in patent: Paragraph 0062; 0063; 0064; 0074
[2] Patent: KR2015/111106, 2015, A. Location in patent: Paragraph 0383-0386
[3] Patent: KR2016/2328, 2016, A. Location in patent: Paragraph 0589-0591
[4] Patent: KR2017/139895, 2017, A. Location in patent: Paragraph 0395; 0414-0419
[5] Green Chemistry, 2012, vol. 14, # 3, p. 661 - 667

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE Suppliers

Americas 1 China 102 Europe 1 Germany 3 India 2 Japan 2 United Kingdom 5 United States 14 Global 130

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

AllyChem Co., Ltd.

Tel: 0411-62313318 13942603642
Fax: 0411-87549748
Email: info@allychem.com
Country: China
ProdList: 1028
Advantage: 65

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Suzhou Lakestar Pharmatech Co., Ltd.

Tel: 0512-63970158-603 18018108880
Fax: 0512-63971078
Email: info@lakestarpharma.com
Country: China
ProdList: 421
Advantage: 59

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Shanghai WeiNie Chemical Technology Co., Ltd.

Tel: 15902145085
Fax: -
Email: 657990292@qq.com
Country: China
ProdList: 668
Advantage: 50

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Boron Technology (Beijing) Co., Ltd.

Tel: 010-010-15313962280 15313962280
Fax: 010-51669040
Email: 3004509780@qq.com
Country: China
ProdList: 824
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

AAB-PHARMA LIMITED

Tel: 025-66800956 18800000000
Fax: qq3325708371
Email: sales@njdmchem.com
Country: China
ProdList: 4200
Advantage: 50

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Hangzhou SuGuan Chemical Technology Co., Ltd.

Tel: 15958048562
Fax: -
Email: 2032153781@qq.com
Country: China
ProdList: 463
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Nanjing holy chemical co., LTD

Tel: 19951936396
Email: 1815156226@qq.com
Country: China
ProdList: 2947
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Springchem New Material Technology Co.,Ltd

Tel: 021-52836897 13917661608
Email: info@spring-chem.com
Country: China
ProdList: 2023
Advantage: 58

Zhengzhou Alfa Chemical Co.,Ltd

Tel: +8618530059196
Email: sale04@alfachem.cn
Country: China
ProdList: 11784
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 8025
Advantage: 58

Amel Pharmatech Corporation

Tel: 027-888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 5000
Advantage: 58

Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
Country: CHINA
ProdList: 7649
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Wuhan Chemwish Technology Co., Ltd

Tel: 027-67849912
Email: sales@chemwish.com
Country: CHINA
ProdList: 10821
Advantage: 58

Less

View Lastest Price from METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 653589-95-8
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-03

Zhuozhou Wenxi import and Export Co., Ltd

Product: METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 653589-95-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 653589-95-8
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%; 99%
Supply Ability: 1kg; 5kg
Release date: 2020-02-03

653589-95-8, METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATERelated Search:

Phenylboronic acid Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate METHYL 4-METHYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 3-Methoxycarbonylphenylboronic acid pinacol ester METHYL 3-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 2-Methoxymethylphenylboronic acid 2-TERT-BUTOXYCARBONYLPHENYLBORONIC ACID PINACOL ESTER 2-METHYLPHENYLBORONIC ACID, PINACOL ESTER 2-BORONOBENZALDEHYDE, PINACOL ESTER 2-Methoxycarbonylphenylboronic acid 2-Ethoxycarbonylphenylboronic acid pinacol ester ETHYL 2-BROMOBENZOATE-6-BORONIC ACID PINACOL ESTER 2-Carboxyphenylboronic acid METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE

3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

2-METHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE

2-(Methoxycarbonyl)benzeneboronic acid, pinacol ester

N-Methyltetrahydrothiophene-3-amine-1,1-dioxidehydrochloride

Methyl 2-(4

Methyl 2-((4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)Methyl)benzoate

Benzoic acid, 2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, Methyl ester

Methyl 2-((4,4

2-(2-Methoxycarbonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester

METHYL 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE ISO 9001：2015 REACH

methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoa...

653589-95-8

Acids and Derivatives

Boron, Nitrile, Thio,& TM-Cpds

blocks

BoronicAcids