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N-Methylleukotriene C4

Product Name
N-Methylleukotriene C4
CAS No.
131391-65-6
Chemical Name
N-Methylleukotriene C4
Synonyms
NMLTC4;N-METHYL LTC4;N-Methylleukotriene C4;FPLBRCJNODNRQZ-UYCXAPQFSA-N;N methyl Leukotriene C4,N-methyl Leukotriene C-4,Nmethyl Leukotriene C4;Glycine, N-methyl-L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-;N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-N-(L-γ-glutamyl)-L-cysteinyl]-N-methylglycine
CBNumber
CB12192012
Molecular Formula
C31H49N3O9S
Formula Weight
639.81
MOL File
131391-65-6.mol
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N-Methylleukotriene C4 Property

Boiling point:
965.7±65.0 °C(Predicted)
Density 
1.202±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; Ethanol:H20 (95:5): 2 mg/ml; PBS (pH 7.2): 100 μg/ml
pka
2.23±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13390
Product name
N-methyl Leukotriene C4
Purity
≥97%
Packaging
25μg
Price
$165
Updated
2024/03/01
Cayman Chemical
Product number
13390
Product name
N-methyl Leukotriene C4
Purity
≥97%
Packaging
50μg
Price
$313
Updated
2024/03/01
Cayman Chemical
Product number
13390
Product name
N-methyl Leukotriene C4
Purity
≥97%
Packaging
100μg
Price
$592
Updated
2024/03/01
TRC
Product number
L330388
Product name
N-methylLeukotrieneC4
Packaging
2.5mg
Price
$1235
Updated
2021/12/16
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N-Methylleukotriene C4 Chemical Properties,Usage,Production

Uses

Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4, however, is rapidly metabolized to LTD4 and LTE4, which makes the characterization of LTC4 pharmacology difficult. N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of LTC4 that is not readily metabolized to LTD4 and LTE4.It acts as a potent and selective CysLT2 receptor agonist exhibiting EC50 values of 122 and > 2,000 nM at the human CysLT2 and CysLT1 receptors, respectively. It has essentially the same potency as LTC4 at both the human and murine receptors CysLT2 receptors. N-methyl LTC4 is potent and active in vivo, causing vascular leak in mice overexpressing the human CysLT2 receptor but not in CysLT2 receptor knockout mice.

Uses

N-methyl Leukotriene C4 is synthetic analog of LTC4 with decreased binding affinity.

N-Methylleukotriene C4 Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methylleukotriene C4 Suppliers

China 16 United States 5 USA 1 Global 22
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
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Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
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58
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
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China
ProdList
11289
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
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Shanghai Universal Biotech Co.,Ltd
Tel
18768175414
Email
gaojun@univ-bio.com
Country
China
ProdList
24998
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24023
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
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131391-65-6, N-Methylleukotriene C4Related Search:

S-PROPYLGLUTATHIONE N-Methylleukotriene C4 11-TRANS LEUKOTRIENE D4 11-TRANS LEUKOTRIENE C4 S-ETHYLGLUTATHIONE S-BUTYLGLUTATHIONE S-PENTYLGLUTATHIONE S-HEXYLGLUTATHIONE

  • N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-N-(L-γ-glutamyl)-L-cysteinyl]-N-methylglycine
  • N-Methylleukotriene C4
  • NMLTC4
  • N-METHYL LTC4
  • FPLBRCJNODNRQZ-UYCXAPQFSA-N
  • Glycine, N-methyl-L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-
  • N methyl Leukotriene C4,N-methyl Leukotriene C-4,Nmethyl Leukotriene C4
  • 131391-65-6
  • C31H49N3O9S