ChemicalBook > CAS DataBase List > [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

Product Name
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
CAS No.
546-78-1
Chemical Name
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
Synonyms
Thujenone;Thujen-2-one;(-)-Umbellulone;(1R,5S)-(-)-3-Thujen-2-one;(-)-Umbellulone >=98% (HPLC);(1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one;[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
CBNumber
CB12235115
Formula Weight
0
MOL File
546-78-1.mol
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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Property

storage temp. 
-20°C
solubility 
DMSO : 250 mg/mL (1664.23 mM; Need ultrasonic)
form 
Oil
color 
colorless to light brown
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
36/37
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0782
Product name
(-)-Umbellulone
Purity
≥98% (HPLC)
Packaging
5mg
Price
$82.9
Updated
2024/03/01
Adipogen Life Sciences
Product number
AG-CN2-0085-M010
Product name
Umbellulone
Purity
≥98%(HPLC)
Packaging
10mg
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0045882
Product name
(-)-UMBELLULONE
Purity
95.00%
Packaging
5MG
Price
$517.66
Updated
2021/12/16
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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Chemical Properties,Usage,Production

Definition

ChEBI: Umbellulone is a ketone.

Biochem/physiol Actions

(-)-Umbellulone, isolated from the"headache tree" Umbellularia californica Nutt, is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. (-)-Umbellulone activates TRPA1 channels on nociceptive trigeminal afferents, resulting in release of CGRP and CGRP-mediated neurogenic vasodilatation, causing a painful cold sensation and headache/migraine.

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Suppliers

China 9 United States 3 Global 12
Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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Energy Chemical
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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Nantong QuanYi Biotechnology Co., Ltd
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sales@chemhifuture.com
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Baoji Didu Pharmaceutical and Chemical Co., Ltd
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02961856358 15829046862
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RD International Technology Co., Limited
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TargetMol Chemicals Inc.
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546-78-1, [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-oneRelated Search:


  • [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
  • (1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one
  • (1R,5S)-(-)-3-Thujen-2-one
  • Thujen-2-one
  • Thujenone
  • (-)-Umbellulone >=98% (HPLC)
  • (-)-Umbellulone
  • 546-78-1